Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS von Bian, Yangyang, Zheng, Runsheng, Bayer, Florian P., Wong, Cassandra, Chang, Yun-Chien, Meng, Chen, Zolg, Daniel P., Reinecke, Maria, Zecha, Jana, Wiechmann, Svenja, Heinzlmeir, Stephanie, Scherr, Johannes, Hemmer, Bernhard, Baynham, Mike, Gingras, Anne-Claude, Boychenko, Oleksandr, Kuster, Bernhard

Volltext

Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion von Martinelli, Silvia, Anderzhanova, Elmira A., Bajaj, Thomas, Wiechmann, Svenja, Dethloff, Frederik, Weckmann, Katja, Heinz, Daniel E., Ebert, Tim, Hartmann, Jakob, Geiger, Thomas M., Döngi, Michael, Hafner, Kathrin, Pöhlmann, Max L., Jollans, Lee, Philipsen, Alexandra, Schmidt, Susanne V., Schmidt, Ulrike, Maccarrone, Giuseppina, Stein, Valentin, Hausch, Felix, Turck, Christoph W., Schmidt, Mathias V., Gellner, Anne-Kathrin, Kuster, Bernhard, Gassen, Nils C.

Volltext

Overcoming the challenges of tissue delivery for oligonucleotide therapeutics von Gökirmak, Tufan, Nikan, Mehran, Wiechmann, Svenja, Prakash, Thazha P., Tanowitz, Michael, Seth, Punit P.

Volltext

IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells von Han, Yingying, Mora, Javier, Huard, Arnaud, da Silva, Priscila, Wiechmann, Svenja, Putyrski, Mateusz, Schuster, Christian, Elwakeel, Eiman, Lang, Guangping, Scholz, Anica, Scholz, Tatjana, Schmid, Tobias, de Bruin, Natasja, Billuart, Pierre, Sala, Carlo, Burkhardt, Harald, Parnham, Michael J., Ernst, Andreas, Brüne, Bernhard, Weigert, Andreas

Volltext

Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome von Wegner, Martin, Diehl, Valentina, Bittl, Verena, de Bruyn, Rahel, Wiechmann, Svenja, Matthess, Yves, Hebel, Marie, Hayes, Michael Gb, Schaubeck, Simone, Benner, Christopher, Heinz, Sven, Bremm, Anja, Dikic, Ivan, Ernst, Andreas, Kaulich, Manuel

Volltext

Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids von Wiechmann, Svenja, Maisonneuve, Pierre, Grebbin, Britta M., Hoffmeister, Meike, Kaulich, Manuel, Clevers, Hans, Rajalingam, Krishnaraj, Kurinov, Igor, Farin, Henner F., Sicheri, Frank, Ernst, Andreas

Volltext

Neutralizing IL-38 activates γδ T cell-dependent antitumor immunity and sensitizes for chemotherapy von da Silva, Priscila, Mora, Javier, You, Xin, Wiechmann, Svenja, Putyrski, Mateusz, Garcia-Pardo, Javier, Kannt, Aimo, Ernst, Andreas, Bruene, Bernhard, Weigert, Andreas

Volltext

Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer von Dietinger, Vanessa, García de Durango, Cira R, Wiechmann, Svenja, Boos, Sophie L, Michl, Marlies, Neumann, Jens, Hermeking, Heiko, Kuster, Bernhard, Jung, Peter

Volltext

Engineering von intrazellulären Modulatoren von Wiechmann, Svenja, Ernst, Andreas

Volltext

2788: Characterization of radiosensitization by kinase inhibition in preclinical pancreatic cancer models von Pangerl, Julia, Spieß, Lukas, Hoffmüller, Patricia, Crocione, Alessia, Kessler, Christopher, Wiechmann, Svenja, Schneider, Günter, Schmid, Roland M., Kuster, Bernhard, Schilling, Daniela, Combs, Stephanie E., Dobiasch, Sophie

Volltext

Decrypting drug actions and protein modifications by dose- and time-resolved proteomics von Zecha, Jana, Bayer, Florian P, Wiechmann, Svenja, Woortman, Julia, Berner, Nicola, Müller, Julian, Schneider, Annika, Kramer, Karl, Abril-Gil, Mar, Hopf, Thomas, Reichart, Leonie, Chen, Lin, Hansen, Fynn M, Lechner, Severin, Samaras, Patroklos, Eckert, Stephan, Lautenbacher, Ludwig, Reinecke, Maria, Hamood, Firas, Prokofeva, Polina, Vornholz, Larsen, Falcomatà, Chiara, Dorsch, Madeleine, Schröder, Ayla, Venhuizen, Anton, Wilhelm, Stephanie, Médard, Guillaume, Stoehr, Gabriele, Ruland, Jürgen, Grüner, Barbara M, Saur, Dieter, Buchner, Maike, Ruprecht, Benjamin, Hahne, Hannes, The, Matthew, Wilhelm, Mathias, Kuster, Bernhard

Volltext

Chemoproteomic Selectivity Profiling of PIKK and PI3K Kinase Inhibitors von Reinecke, Maria, Ruprecht, Benjamin, Poser, Sandra, Wiechmann, Svenja, Wilhelm, Mathias, Heinzlmeir, Stephanie, Kuster, Bernhard, Médard, Guillaume

Volltext

Radiosensitization by Kinase Inhibition Revealed by Phosphoproteomic Analysis of Pancreatic Cancer Cells von Wiechmann, Svenja, Saupp, Elena, Schilling, Daniela, Heinzlmeir, Stephanie, Schneider, Günter, Schmid, Roland M., Combs, Stephanie E., Kuster, Bernhard, Dobiasch, Sophie

Volltext

Chemical Phosphoproteomics Sheds New Light on the Targets and Modes of Action of AKT Inhibitors von Wiechmann, Svenja, Ruprecht, Benjamin, Siekmann, Theresa, Zheng, Runsheng, Frejno, Martin, Kunold, Elena, Bajaj, Thomas, Zolg, Daniel P, Sieber, Stephan A, Gassen, Nils C, Kuster, Bernhard

Volltext

Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation von Wiechmann, Svenja, Gärtner, Anne, Kniss, Andreas, Stengl, Andreas, Behrends, Christian, Rogov, Vladimir V., Rodriguez, Manuel S., Dötsch, Volker, Müller, Stefan, Ernst, Andreas

Volltext

Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids von Wiechmann, Svenja, Maisonneuve, Pierre, Grebbin, Britta M, Hoffmeister, Meike, Kaulich, Manuel, Clevers, Hans, Rajalingam, Krishnaraj, Kurinov, Igor, Farin, Henner F, Sicheri, Frank, Ernst, Andreas

Volltext

Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice von Stepan, Jens, Heinz, Daniel E, Dethloff, Frederik, Wiechmann, Svenja, Martinelli, Silvia, Hafner, Kathrin, Ebert, Tim, Junglas, Ellen, Häusl, Alexander S, Pöhlmann, Max L, Jakovcevski, Mira, Pape, Julius C, Zannas, Anthony S, Bajaj, Thomas, Hermann, Anke, Ma, Xiao, Pavenstädt, Hermann, Schmidt, Mathias V, Philipsen, Alexandra, Turck, Christoph W, Deussing, Jan M, Rammes, Gerhard, Robinson, Andrew C, Payton, Antony, Wehr, Michael C, Stein, Valentin, Murgatroyd, Christopher, Kremerskothen, Joachim, Kuster, Bernhard, Wotjak, Carsten T, Gassen, Nils C

Volltext

Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice von Stepan, Jens, Heinz, Daniel E, Dethloff, Frederik, Wiechmann, Svenja, Martinelli, Silvia, Hafner, Kathrin, Ebert, Tim, Junglas, Ellen, Häusl, Alexander S, Pöhlmann, Max L, Jakovcevski, Mira, Pape, Julius C, Zannas, Anthony S, Bajaj, Thomas, Hermann, Anke, Ma, Xiao, Pavenstädt, Hermann, Schmidt, Mathias V, Philipsen, Alexandra, Turck, Christoph W, Deussing, Jan M, Rammes, Gerhard, Robinson, Andrew C, Payton, Antony, Wehr, Michael C, Stein, Valentin, Murgatroyd, Christopher, Kremerskothen, Joachim, Kuster, Bernhard, Wotjak, Carsten T, Gassen, Nils C

Volltext

Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC-MS/MS von Bian, Yangyang, Zheng, Runsheng, Bayer, Florian P, Wong, Cassandra, Chang, Yun-Chien, Meng, Chen, Zolg, Daniel P, Reinecke, Maria, Zecha, Jana, Wiechmann, Svenja, Heinzlmeir, Stephanie, Scherr, Johannes, Hemmer, Bernhard, Baynham, Mike, Gingras, Anne-Claude, Boychenko, Oleksandr, Kuster, Bernhard

Volltext

Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning von Stepan, Jens, Heinz, Daniel E., Dethloff, Frederik, Bajaj, Thomas, Zellner, Andreas, Hafner, Kathrin, Wiechmann, Svenja, Mackert, Sarah, Mecdad, Yara, Rabenstein, Michael, Ebert, Tim, Martinelli, Silvia, Häusl, Alexander S., Pöhlmann, Maximilian L., Hermann, Anke, Ma, Xiao, Pavenstädt, Hermann, Schmidt, Mathias V., Philipsen, Alexandra, Turck, Chris W., Deussing, Jan M., Kuster, Bernhard, Wehr, Michael C., Stein, Valentin, Kremerskothen, Joachim, Wotjak, Carsten T., Gassen, Nils C.

Volltext