Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a von Fukuda, Tetsuya, Chen, Liguang, Endo, Tomoyuki, Tang, Li, Lu, Desheng, Castro, Januario E, Widhopf, George F. II, Rassenti, Laura Z, Cantwell, Mark J, Prussak, Charles E, Carson, Dennis A, Kipps, Thomas J

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Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody von Zhang, Suping, Zhang, Han, Ghia, Emanuela M., Huang, Jiajia, Wu, Liufeng, Zhang, Jianchao, Lam, Sharon, Lei, Yang, He, Jinsong, Cui, Bing, Widhopf, George F., Yu, Jian, Schwab, Richard, Messer, Karen, Jiang, Wenqi, Parker, Barbara A., Carson, Dennis A., Kipps, Thomas J.

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Wnt5a enhances proliferation of chronic lymphocytic leukemia and ERK1/2 phosphorylation via a ROR1/DOCK2-dependent mechanism von Hasan, Md Kamrul, Ghia, Emanuela M., Rassenti, Laura Z., Widhopf, George F., Kipps, Thomas J.

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Targeting ROR1 Inhibits Epithelial―Mesenchymal Transition and Metastasis von BING CUI, SUPING ZHANG, LIGUANG CHEN, JIANQIANG YU, WIDHOPF, George F, FECTEAU, Jessie-F, RASSENTI, Laura Z, KIPPS, Thomas J

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Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy von Zhang, Suping, Cui, Bing, Lai, Hsien, Liu, Grace, Ghia, Emanuela M., Widhopf, George F., Zhang, Zhuhong, Wu, Christina C. N., Chen, Liguang, Wu, Rongrong, Schwab, Richard, Carson, Dennis A., Kipps, Thomas J.

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A phase 1b study of zilovertamab in combination with paclitaxel for locally advanced/unresectable or metastatic Her2-negative breast cancer von Shatsky, Rebecca A, Batra-Sharma, Hemali, Helsten, Teresa, Schwab, Richard B, Pittman, Emily I, Pu, Minya, Weihe, Elizabeth, Ghia, Emanuela M, Rassenti, Laura Z, Molinolo, Alfredo, Cabrera, Betty, Breitmeyer, James B, Widhopf, 2nd, George F, Messer, Karen, Jamieson, Catriona, Kipps, Thomas J, Parker, Barbara A

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Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia von Choi, Michael Y., Widhopf, George F., Ghia, Emanuela M., Kidwell, Reilly L., Hasan, Md Kamrul, Yu, Jian, Rassenti, Laura Z., Chen, Liguang, Chen, Yun, Pittman, Emily, Pu, Minya, Messer, Karen, Prussak, Charles E., Castro, Januario E., Jamieson, Catriona, Kipps, Thomas J.

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Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations von Deniger, Drew C, Yu, Jianqiang, Huls, M Helen, Figliola, Matthew J, Mi, Tiejuan, Maiti, Sourindra N, Widhopf, 2nd, George F, Hurton, Lenka V, Thokala, Radhika, Singh, Harjeet, Olivares, Simon, Champlin, Richard E, Wierda, William G, Kipps, Thomas J, Cooper, Laurence J N

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Cirmtuzumab blocks Wnt5a/ROR1 stimulation of NF-κB to repress autocrine STAT3 activation in chronic lymphocytic leukemia von Chen, Yun, Chen, Liguang, Yu, Jian, Ghia, Emanuela M., Choi, Michael Y., Zhang, Ling, Zhang, Suping, Sanchez-Lopez, Elsa, Widhopf, George F., Messer, Karen, Rassenti, Laura Z., Jamieson, Catriona, Kipps, Thomas J.

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High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia von Cui, Bing, Ghia, Emanuela M., Chen, Liguang, Rassenti, Laura Z., DeBoever, Christopher, Widhopf, George F., Yu, Jian, Neuberg, Donna S., Wierda, William G., Rai, Kanti R., Kay, Neil E., Brown, Jennifer R., Jones, Jeffrey A., Gribben, John G., Frazer, Kelly A., Kipps, Thomas J.

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Correction: a phase 1b study of zilovertamab in combination with paclitaxel for locally advanced/unresectable or metastatic HER2-negative breast cancer von Shatsky, Rebecca A, Batra-Sharma, Hemali, Helsten, Teresa, Schwab, Richard B, Pittman, Emily I, Pu, Minya, Weihe, Elizabeth, Ghia, Emanuela M, Rassenti, Laura Z, Molinolo, Alfredo, Cabrera, Betty, Breitmeyer, James B, Widhopf Ii, George F, Messer, Karen, Jamieson, Catriona, Kipps, Thomas J, Parker, Barbara A

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Wnt5a causes ROR1 to complex and activate cortactin to enhance migration of chronic lymphocytic leukemia cells von Hasan, Md Kamrul, Rassenti, Laura, Widhopf, George F., Yu, Jian, Kipps, Thomas J.

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Pre-clinical Specificity and Safety of UC-961, a First-In-Class Monoclonal Antibody Targeting ROR1 von Choi, Michael Y, Widhopf, George F, Wu, Christina C.N, Cui, Bing, Lao, Fitzgerald, Sadarangani, Anil, Cavagnaro, Joy, Prussak, Charles, Carson, Dennis A, Jamieson, Catriona, Kipps, Thomas J

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Variant Transcript of ROR1 ENST00000545203 Does Not Encode ROR1 Protein von Xian, Jie, Sinha, Navyaa, Girgis, Christina, Oh, Christopher S, Cring, Matthew R, Widhopf, 2nd, George F, Kipps, Thomas J

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High expression level of ROR1 and ROR1-signaling associates with venetoclax resistance in chronic lymphocytic leukemia von Ghia, Emanuela M., Rassenti, Laura Z., Choi, Michael Y., Quijada-Álamo, Miguel, Chu, Elvin, Widhopf, George F., Kipps, Thomas J.

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Dielectrophoretic isolation and detection of cancer-related circulating cell-free DNA biomarkers from blood and plasma von Sonnenberg, Avery, Marciniak, Jennifer Y., Skowronski, Elaine A., Manouchehri, Sareh, Rassenti, Laura, Ghia, Emanuela M., Widhopf II, George F., Kipps, Thomas J., Heller, Michael J.

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Rapid electrokinetic isolation of cancer-related circulating cell-free DNA directly from blood von Sonnenberg, Avery, Marciniak, Jennifer Y, Rassenti, Laura, Ghia, Emanuela M, Skowronski, Elaine A, Manouchehri, Sareh, McCanna, James, Widhopf, 2nd, George F, Kipps, Thomas J, Heller, Michael J

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Wnt5a induces ROR1 to recruit DOCK2 to activate Rac1/2 in chronic lymphocytic leukemia von Hasan, Md Kamrul, Yu, Jian, Widhopf, George F., Rassenti, Laura Z., Chen, Liguang, Shen, Zhouxin, Briggs, Steven P., Neuberg, Donna S., Kipps, Thomas J.

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MicroRNA dysregulation to identify therapeutic target combinations for chronic lymphocytic leukemia von Rassenti, Laura Z., Balatti, Veronica, Ghia, Emanuela M., Palamarchuk, Alexey, Tomasello, Luisa, Fadda, Paolo, Pekarsky, Yuri, Widhopf, George F., Kipps, Thomas J., Croce, Carlo M.

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Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation von Yu, Jian, Chen, Liguang, Cui, Bing, Widhopf, 2nd, George F, Shen, Zhouxin, Wu, Rongrong, Zhang, Ling, Zhang, Suping, Briggs, Steven P, Kipps, Thomas J

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