AND-gate contrast agents for enhanced fluorescence-guided surgery von Widen, John C., Tholen, Martina, Yim, Joshua J., Antaris, Alexander, Casey, Kerriann M., Rogalla, Stephan, Klaassen, Alwin, Sorger, Jonathan, Bogyo, Matthew

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Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions von Jackson, Paul A, Widen, John C, Harki, Daniel A, Brummond, Kay M

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SN-38 Conjugated Gold Nanoparticles Activated by Ewing Sarcoma Specific mRNAs Exhibit In Vitro and In Vivo Efficacy von Naumann, Jordan A, Widen, John C, Jonart, Leslie A, Ebadi, Maryam, Tang, Jian, Gordon, David J, Harki, Daniel A, Gordon, Peter M

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Methods for analysis of near-infrared (NIR) quenched-fluorescent contrast agents in mouse models of cancer von Widen, John C, Tholen, Martina, Yim, Joshua J, Bogyo, Matthew

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The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection von Richards, Christopher M, Jabs, Sabrina, Qiao, Wenjie, Varanese, Lauren D, Schweizer, Michaela, Mosen, Peter R, Riley, Nicholas M, Klüssendorf, Malte, Zengel, James R, Flynn, Ryan A, Rustagi, Arjun, Widen, John C, Peters, Christine E, Ooi, Yaw Shin, Xie, Xuping, Shi, Pei-Yong, Bartenschlager, Ralf, Puschnik, Andreas S, Bogyo, Matthew, Bertozzi, Carolyn R, Blish, Catherine A, Winter, Dominic, Nagamine, Claude M, Braulke, Thomas, Carette, Jan E

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Molecular Basis for the N‑Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase–Bromodomain Inhibitor von Divakaran, Anand, Talluri, Siva K, Ayoub, Alex M, Mishra, Neeraj K, Cui, Huarui, Widen, John C, Berndt, Norbert, Zhu, Jin-Yi, Carlson, Angela S, Topczewski, Joseph J, Schonbrunn, Ernst K, Harki, Daniel A, Pomerantz, William C. K

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Challenges for Targeting SARS-CoV‑2 Proteases as a Therapeutic Strategy for COVID-19 von Steuten, Kas, Kim, Heeyoung, Widen, John C, Babin, Brett M, Onguka, Ouma, Lovell, Scott, Bolgi, Oguz, Cerikan, Berati, Neufeldt, Christopher J, Cortese, Mirko, Muir, Ryan K, Bennett, John M, Geiss-Friedlander, Ruth, Peters, Christoph, Bartenschlager, Ralf, Bogyo, Matthew

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A synthetic covalent ligand of the C/EBPβ transactivation domain inhibits acute myeloid leukemia cells von Abdel Ghani, Luca, Yusenko, Maria V., Frank, Daria, Moorthy, Ramkumar, Widen, John C., Dörner, Wolfgang, Khandanpour, Cyrus, Harki, Daniel A., Klempnauer, Karl-Heinz

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Synthesis of Guaianolide Analogues with a Tunable α‑Methylene−γ-lactam Electrophile and Correlating Bioactivity with Thiol Reactivity von Jackson, Paul A, Schares, Henry A. M, Jones, Katherine F. M, Widen, John C, Dempe, Daniel P, Grillet, Francois, Cuellar, Matthew E, Walters, Michael A, Harki, Daniel A, Brummond, Kay M

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Targeting NF-κB p65 with a Helenalin Inspired Bis-electrophile von Widen, John C, Kempema, Aaron M, Villalta, Peter W, Harki, Daniel A

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Alkyne Ligation Handles: Propargylation of Hydroxyl, Sulfhydryl, Amino, and Carboxyl Groups via the Nicholas Reaction von Wells, Sarah M, Widen, John C, Harki, Daniel A, Brummond, Kay M

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Protease Activated Probes for Real-Time Ratiometric Imaging of Solid Tumors von Faucher, Franco F., Liu, Kevin J., Cosco, Emily D., Widen, John C., Sorger, Jonathan, Guerra, Matteo, Bogyo, Matthew

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A Redox Economical Synthesis of Bioactive 6,12-Guaianolides von Wen, Bo, Hexum, Joseph K, Widen, John C, Harki, Daniel A, Brummond, Kay M

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Helenalin Analogues Targeting NF‐κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles von Widen, John C., Kempema, Aaron M., Baur, Jordan W., Skopec, Hannah M., Edwards, Jacob T., Brown, Tenley J., Brown, Dennis A., Meece, Frederick A., Harki, Daniel A.

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Tetrapyridyl tetraphenylethylenes: supramolecular building blocks with aggregation-induced emission properties von Kapadia, Pradeep P., Widen, John C., Magnus, Mackenzie A., Swenson, Dale C., Pigge, F. Christopher

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Synthesis and antileukemic activities of C1–C10-modified parthenolide analogues von Kempema, Aaron M., Widen, John C., Hexum, Joseph K., Andrews, Timothy E., Wang, Dan, Rathe, Susan K., Meece, Frederick A., Noble, Klara E., Sachs, Zohar, Largaespada, David A., Harki, Daniel A.

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Front Cover: Helenalin Analogues Targeting NF‐κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles (ChemMedChem 4/2018) von Widen, John C., Kempema, Aaron M., Baur, Jordan W., Skopec, Hannah M., Edwards, Jacob T., Brown, Tenley J., Brown, Dennis A., Meece, Frederick A., Harki, Daniel A.

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KRAS G12C INHIBITORS von PATEL, Snahel, WILLIAMS, Monika Jane, GERKEN, Philip A, ERLANSON, Daniel A, DOTSENKO, Irina, TANAKA, Hiroko, WIDEN, John C

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KRAS G12C INHIBITORS von PATEL, Snahel, WILLIAMS, Monika Jane, GERKEN, Philip A, ERLANSON, Daniel A, DOTSENKO, Irina, TANAKA, Hiroko, WIDEN, John C

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Kras g12c inhibitors von DOTSENKO Irina, GERKEN Philip A, PATEL Snahel, ERLANSON Daniel A, TANAKA Hiroko, WIDEN John C, WILLIAMS Monika Jane

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