Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1 von Feldman, Richard I., Wu, James M., Polokoff, Mark A., Kochanny, Monica J., Dinter, Harald, Zhu, Daguang, Biroc, Sandra L., Alicke, Bruno, Bryant, Judi, Yuan, Shendong, Buckman, Brad O., Lentz, Dao, Ferrer, Mike, Whitlow, Marc, Adler, Marc, Finster, Silke, Chang, Zheng, Arnaiz, Damian O.

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Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa von Adler, Marc, Kochanny, Monica J, Ye, Bin, Rumennik, Galina, Light, David R, Biancalana, Sara, Whitlow, Marc

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Allosteric Inhibitors of Inducible Nitric Oxide Synthase Dimerization Discovered via Combinatorial Chemistry von McMillan, Kirk, Adler, Marc, Auld, Douglas S., Baldwin, John J., Blasko, Eric, Browne, Leslie J., Chelsky, Daniel, Davey, David, Dolle, Ronald E., Eagen, Keith A., Erickson, Shawn, Feldman, Richard I., Glaser, Charles B., Mallari, Cornell, Morrissey, Michael M., Michael H. J. Ohlmeyer, Pan, Gonghua, Parkinson, John F., Phillips, Gary B., Polokoff, Mark A., Sigal, Nolan H., Vergona, Ronald, Whitlow, Marc, Young, Tish A., Devlin, James J.

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Thiophene-Anthranilamides as Highly Potent and Orally Available Factor Xa Inhibitors von Ye, Bin, Arnaiz, Damian O, Chou, Yuo-Ling, Griedel, Brian D, Karanjawala, Rushad, Lee, Wheeseong, Morrissey, Michael M, Sacchi, Karna L, Sakata, Steven T, Shaw, Kenneth J, Wu, Shung C, Zhao, Zuchun, Adler, Marc, Cheeseman, Sarah, Dole, William P, Ewing, Janice, Fitch, Richard, Lentz, Dao, Liang, Amy, Light, David, Morser, John, Post, Joseph, Rumennik, Galina, Subramanyam, Babu, Sullivan, Mark E, Vergona, Ron, Walters, Janette, Wang, Yi-Xin, White, Kathy A, Whitlow, Marc, Kochanny, Monica J

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Mechanistic Studies with Potent and Selective Inducible Nitric-oxide Synthase Dimerization Inhibitors von Blasko, Eric, Glaser, Charles B., Devlin, James J., Xia, Wei, Feldman, Richard I., Polokoff, Mark A., Phillips, Gary B., Whitlow, Marc, Auld, Douglas S., McMillan, Kirk, Ghosh, Sanjay, Stuehr, Dennis J., Parkinson, John F.

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Potent Triazolothione Inhibitor of Heat-Shock Protein-90 von Feldman, Richard I, Mintzer, Bob, Zhu, Daguang, Wu, James M, Biroc, Sandra L, Yuan, Shendong, Emayan, Kumar, Chang, Zheng, Chen, Deborah, Arnaiz, Damian O, Bryant, Judi, Ge, Xue Snow, Whitlow, Marc, Adler, Marc, Polokoff, Mark A, Li, Wei-Wei, Ferrer, Mike, Sato, Takashi, Gu, Jian-Ming, Shen, Jun, Tseng, Jih-Lie, Dinter, Harald, Buckman, Brad

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A Novel, Highly Stable Fold of the Immunoglobulin Binding Domain of Streptococcal Protein G von Gronenborn, Angela M., Filpula, David R., Essig, Nina Z., Achari, Aniruddha, Whitlow, Marc, Wingfield, Paul T., Clore, G. Marius

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A model of the acid sphingomyelinase phosphoesterase domain based on its remote structural homolog purple acid phosphatase von Seto, Marian, Whitlow, Marc, McCarrick, Margaret A., Srinivasan, Subha, Zhu, Ying, Pagila, Rene, Mintzer, Robert, Light, David, Johns, Anthony, Meurer‐Ogden, Janet A.

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Single-Chain Antigen-Binding Proteins von Bird, Robert E., Hardman, Karl D., Jacobson, James W., Johnson, Syd, Kaufman, Bennett M., Lee, Shwu-Maan, Lee, Timothy, Pope, Sharon H., Riordan, Gary S., Whitlow, Marc

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1.85 Å structure of anti-fluorescein 4-4-20 Fab von Whitlow, Marc, Howard, Andrew J., Wood, Jay F., Voss, Edward W., Hardman, Karl D.

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Design, Synthesis, and Activity of 2,6-Diphenoxypyridine-Derived Factor Xa Inhibitors von Phillips, Gary, Davey, David D, Eagen, Keith A, Koovakkat, Sunil K, Liang, Amy, Ng, Howard P, Pinkerton, Michael, Trinh, Lan, Whitlow, Marc, Beatty, Alicia M, Morrissey, Michael M

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Design, Synthesis, and Activity of a Novel Series of Factor Xa Inhibitors:  Optimization of Arylamidine Groups von Phillips, Gary, Guilford, William J, Buckman, Brad O, Davey, David D, Eagen, Keith A, Koovakkat, Sunil, Liang, Amy, McCarrick, Meg, Mohan, Raju, Ng, Howard P, Pinkerton, Michael, Subramanyam, Babu, Ho, Elena, Trinh, Lan, Whitlow, Marc, Wu, Shung, Xu, Wei, Morrissey, Michael M

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Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding von Pantoliano, Michael W, Whitlow, Marc, Wood, Jay F, Dodd, Steven W, Hardman, Karl D, Rollence, Michele L, Bryan, Philip N

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ASP2408 and ASP2409, novel CTLA4-Ig variants with CD86-selective ligand binding activity and improved immunosuppressive potency, created by directed evolution von Oshima, Shinsuke, Karrer, Erik E., Paidhungat, Madan M., Neighbors, Margaret, Chapin, Steven J., Fan, Rong A., Reed, Margaret A., Wu, Kuoting, Wong, Clifford, Chen, Yonghong, Whitlow, Marc, Anderson, Francisco A., Bam, Rujuta A., Zhang, Qian, Larsen, Brent R., Viswanathan, Sridhar, Devens, Bruce H., Bass, Steven H., Higashi, Yasuyuki

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Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synth... von Li, H, Raman, C S, Glaser, C B, Blasko, E, Young, T A, Parkinson, J F, Whitlow, M, Poulos, T L

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Structural Comparability Between Recombinant FVIII-Fc and Its Isolated FVIII and Fc Constituents von Kulman, John, Tsutakawa, Susan, Bou-Assaf, George, Berkowitz, Steven, Light, David R., Mezo, Adam, Wang, Deping, Whitlow, Marc, Culyba, Liz, Tainer, John, Peters, Robert

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The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case von Pantoliano, Michael W, Whitlow, Marc, Wood, Jay F, Rollence, Michele L, Finzel, Barry C, Gilliland, Gary L, Poulos, Thomas L, Bryan, Philip N

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RAPID TUMOR PENETRATION OF A SINGLE-CHAIN FV AND COMPARISON WITH OTHER IMMUNOGLOBULIN FORMS von YOKOTA, T, MILENIC, DE, WHITLOW, M, SCHLOM, J

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Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A(4) hydrolase von Kirkland, Thomas A., Adler, Marc, Bauman, John G., Chen, Ming, Haeggstrom, Jesper Z., King, Beverly, Kochanny, Monica J., Liang, Amy M., Mendoza, Lisa, Phillips, Gary B., Thunnissen, Marjolein, Trinh, Lan, Whitlow, Marc, Ye, Bin, Ye, Hong, Parkinson, John, Guilford, William J.

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Mapping the binding site of aflatoxin B1 in DNA: systematic analysis of the reactivity of aflatoxin B1 with guanines in different DNA sequences von Benasutti, Matt, Ejadi, Samuel, Whitlow, Marc D, Loechler, Edward L

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