Understanding how cis-regulatory function is encoded in DNA sequence using massively parallel reporter assays and designed sequences von White, Michael A.

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Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase von Pineda, Carlos T., Ramanathan, Saumya, Fon Tacer, Klementina, Weon, Jenny L., Potts, Malia B., Ou, Yi-Hung, White, Michael A., Potts, Patrick Ryan

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Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets von Witkiewicz, Agnieszka K., McMillan, Elizabeth A., Balaji, Uthra, Baek, GuemHee, Lin, Wan-Chi, Mansour, John, Mollaee, Mehri, Wagner, Kay-Uwe, Koduru, Prasad, Yopp, Adam, Choti, Michael A., Yeo, Charles J., McCue, Peter, White, Michael A., Knudsen, Erik S.

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Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non-Small-Cell Lung Cancer von Kim, Hyun Seok, Mendiratta, Saurabh, Kim, Jiyeon, Pecot, Chad Victor, Larsen, Jill E., Zubovych, Iryna, Seo, Bo Yeun, Kim, Jimi, Eskiocak, Banu, Chung, Hannah, McMillan, Elizabeth, Wu, Sherry, De Brabander, Jef, Komurov, Kakajan, Toombs, Jason E., Wei, Shuguang, Peyton, Michael, Williams, Noelle, Gazdar, Adi F., Posner, Bruce A., Brekken, Rolf A., Sood, Anil K., Deberardinis, Ralph J., Roth, Michael G., Minna, John D., White, Michael A.

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Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells von Chen, Pei-Hsuan, Cai, Ling, Huffman, Kenneth, Yang, Chendong, Kim, Jiyeon, Faubert, Brandon, Boroughs, Lindsey, Ko, Bookyung, Sudderth, Jessica, McMillan, Elizabeth A., Girard, Luc, Chen, Dong, Peyton, Michael, Shields, Misty D., Yao, Bo, Shames, David S., Kim, Hyun Seok, Timmons, Brenda, Sekine, Ikuo, Britt, Rebecca, Weber, Stephanie, Byers, Lauren A., Heymach, John V., Chen, Jing, White, Michael A., Minna, John D., Xiao, Guanghua, DeBerardinis, Ralph J.

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Massively parallel in vivo enhancer assay reveals that highly local features determine the cis-regulatory function of ChIP-seq peaks von White, Michael A, Myers, Connie A, Corbo, Joseph C, Cohen, Barak A

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Assembly of the threespine stickleback Y chromosome reveals convergent signatures of sex chromosome evolution von Peichel, Catherine L., McCann, Shaugnessy R., Ross, Joseph A., Naftaly, Alice F. S., Urton, James R., Cech, Jennifer N., Grimwood, Jane, Schmutz, Jeremy, Myers, Richard M., Kingsley, David M., White, Michael A.

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MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies von Baek, GuemHee, Tse, Yan F., Hu, Zeping, Cox, Derek, Buboltz, Noah, McCue, Peter, Yeo, Charles J., White, Michael A., DeBerardinis, Ralph J., Knudsen, Erik S., Witkiewicz, Agnieszka K.

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Purifying Selection Maintains Dosage-Sensitive Genes during Degeneration of the Threespine Stickleback Y Chromosome von White, Michael A, Kitano, Jun, Peichel, Catherine L

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A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients von Tang, Hao, Xiao, Guanghua, Behrens, Carmen, Schiller, Joan, Allen, Jeffrey, Chow, Chi-Wan, Suraokar, Milind, Corvalan, Alejandro, Mao, Jianhua, White, Michael A, Wistuba, Ignacio I, Minna, John D, Xie, Yang

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SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers von Tagal, Vural, Wei, Shuguang, Zhang, Wei, Brekken, Rolf A., Posner, Bruce A., Peyton, Michael, Girard, Luc, Hwang, TaeHyun, Wheeler, David A., Minna, John D., White, Michael A., Gazdar, Adi F., Roth, Michael G.

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The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies von Li, Zenggang, Ivanov, Andrei A., Su, Rina, Gonzalez-Pecchi, Valentina, Qi, Qi, Liu, Songlin, Webber, Philip, McMillan, Elizabeth, Rusnak, Lauren, Pham, Cau, Chen, Xiaoqian, Mo, Xiulei, Revennaugh, Brian, Zhou, Wei, Marcus, Adam, Harati, Sahar, Chen, Xiang, Johns, Margaret A., White, Michael A., Moreno, Carlos S., Cooper, Lee A. D., Du, Yuhong, Khuri, Fadlo R., Fu, Haian

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Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer von McMillan, Elizabeth A., Ryu, Myung-Jeom, Diep, Caroline H., Mendiratta, Saurabh, Clemenceau, Jean R., Vaden, Rachel M., Kim, Ju-Hwa, Motoyaji, Takashi, Covington, Kyle R., Peyton, Michael, Huffman, Kenneth, Wu, Xiaofeng, Girard, Luc, Sung, Yeojin, Chen, Pei-Hsaun, Mallipeddi, Prema L., Lee, Joo Young, Hanson, Jordan, Voruganti, Sukesh, Yu, Yunku, Park, Sunho, Sudderth, Jessica, DeSevo, Christopher, Muzny, Donna M., Doddapaneni, HarshaVardhan, Gazdar, Adi, Gibbs, Richard A., Hwang, Tae-Hyun, Heymach, John V., Wistuba, Ignacio, Coombes, Kevin R., Williams, Noelle S., Wheeler, David A., MacMillan, John B., Deberardinis, Ralph J., Roth, Michael G., Posner, Bruce A., Minna, John D., Kim, Hyun Seok, White, Michael A.

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Digitization of Endocytic pH by Hybrid Ultra‐pH‐Sensitive Nanoprobes at Single‐Organelle Resolution von Wang, Yiguang, Wang, Chensu, Li, Yang, Huang, Gang, Zhao, Tian, Ma, Xinpeng, Wang, Zhaohui, Sumer, Baran D., White, Michael A., Gao, Jinming

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Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan von Wang, Chensu, Niederstrasser, Hanspeter, Douglas, Peter M., Lin, Rueyling, Jaramillo, Juan, Li, Yang, Oswald, Nathaniel W., Zhou, Anwu, McMillan, Elizabeth A., Mendiratta, Saurabh, Wang, Zhaohui, Zhao, Tian, Lin, Zhiqaing, Luo, Min, Huang, Gang, Brekken, Rolf A., Posner, Bruce A., MacMillan, John B., Gao, Jinming, White, Michael A.

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Variations in atmospheric CO₂ growth rates coupled with tropical temperature von Wang, Weile, Ciais, Philippe, Nemani, Ramakrishna R., Canadell, Josep G., Piao, Shilong, Sitch, Stephen, White, Michael A., Hashimoto, Hirofumi, Milesi, Cristina, Myneni, Ranga B.

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TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation von Ou, Yi-Hung, Torres, Michael, Ram, Rosalyn, Formstecher, Etienne, Roland, Christina, Cheng, Tzuling, Brekken, Rolf, Wurz, Ryan, Tasker, Andrew, Polverino, Tony, Tan, Seng-Lai, White, Michael A.

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Transcription factor interactions explain the context-dependent activity of CRX binding sites von Loell, Kaiser J, Friedman, Ryan Z, Myers, Connie A, Corbo, Joseph C, Cohen, Barak A, White, Michael A

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Disrupted Gene Networks in Subfertile Hybrid House Mice von Morgan, Katy, Harr, Bettina, White, Michael A, Payseur, Bret A, Turner, Leslie M

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Synthetic lethal screen identification of chemosensitizer loci in cancer cells von Peyton, Michael, Bodemann, Brian O, Minna, John D, Hao, Weihua, Ferguson, Deborah, White, Michael A, Xie, Xian-Jin, Cardenas, Jessica, Roth, Michael G, Girard, Luc, Michnoff, Carolyn, Whitehurst, Angelique W

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