Factors associated with HD CAG repeat instability in Huntington disease von Wheeler, V C, Persichetti, F, McNeil, S M, Mysore, J S, Mysore, S S, MacDonald, M E, Myers, R H, Gusella, J F, Wexler, N S

Volltext

Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice von Wheeler, Vanessa C., Gutekunst, Claire-Anne, Vrbanac, Vladimir, Lebel, Lori-Anne, Schilling, Gabriele, Hersch, Steven, Friedlander, Robert M., Gusella, James F., Vonsattel, Jean-Paul, Borchelt, David R., MacDonald, Marcy E.

Volltext

Length-Dependent Gametic CAG Repeat Instability in the Huntington's Disease Knock-in Mouse von Wheeler, Vanessa C., Auerbach, Wojtek, White, Jacqueline K., Srinidhi, Jayalakshmi, Auerbach, Anna, Ryan, Angela, Duyao, Mabel P., Vrbanac, Vladimir, Weaver, Meredith, Gusella, James F., Joyner, Alexandra L., MacDonald, Marcy E.

Volltext

Neocortical neurons cultured from mice with expanded cag repeats in the huntingtin gene: unaltered vulnerability to excitotoxins and other insults von Snider, B.J, Moss, J.L, Revilla, F.J, Lee, C.-S, Wheeler, V.C, Macdonald, M.E, Choi, D.W

Volltext

Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells von Trettel, F, Rigamonti, D, Hilditch-Maguire, P, Wheeler, V C, Sharp, A H, Persichetti, F, Cattaneo, E, MacDonald, M E

Volltext

The HD mutation causes progressive lethal neurological disease in mice expressing reduced levels of huntingtin von AUERBACH, Wojtek, HURLBERT, Marc S, HILDITCH-MAGUIRE, Paige, WADGHIRI, Youssef Zaim, WHEELER, Vanessa C, COHEN, Sara I, JOYNER, Alexandra L, MACDONALD, Marcy E, TURNBULL, Daniel H

Volltext

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice von WHEELER, V. C, WHITE, J. K, HERSCH, S, AUERBACH, W, JOYNER, A. L, MACDONALD, M. E, GUTEKUNST, C.-A, VRBANAC, V, WEAVER, M, LI, X.-J, LI, S.-H, HONG YI, VONSATTEL, J.-P, GUSELLA, J. F

Volltext

Huntington's disease von MacDonald, Marcy E, Gines, Silvia, Gusella, James F, Wheeler, Vanessa C

Volltext

A11 Induced pluripotent stem cells for basic and translational research on HD von Mattis, VB, Svendsen, SP, Ebert, A, Svendsen, CN, King, AR, Casale, M, Winokur, ST, Batugedara, G, Vawter, M, Donovan, PJ, Lock, LF, Thompson, LM, Zhu, Y, Fossale, E, Atwal, RS, Gillis, T, Mysore, J, Li, J-h, Seong, IS, Shen, Y, Chen, X, Wheeler, VC, MacDonald, Marcy E, Gusella, JF, Akimov, S, Arbez, N, Juopperi, T, Ratovitski, T, Chiang, JH, Kim, WR, Chighladze, E, Watkin, E, Zhong, C, Makri, G, Cole, RN, Margolis, RL, Song, H, Ming, G, Ross, CA, Kaye, JA, Daub, A, Sharma, P, Mason, AR, Finkbeiner, S, Yu, J, Thomson, JA, Rushton, D, Brazier, SP, Battersby, AA, Redfern, A, Tseng, H-E, Harrison, AW, Kemp, PJ, Allen, ND, Onorati, M, Castiglioni, V, Cattaneo, E, Arjomand, J

Volltext

Identification of a presymptomatic molecular phenotype in Hdh CAG knock-in mice von Fossale, Elisa, Wheeler, Vanessa C., Vrbanac, Vladimir, Lebel, Lori-Anne, Teed, Allison, Mysore, Jayalakshmi S., Gusella, James F., MacDonald, Marcy E., Persichetti, Francesca

Volltext

Mismatch repair gene Msh2 modifies the timing of early disease in HdhQ111 striatum von Wheeler, Vanessa C., Lebel, Lori-Anne, Vrbanac, Vladimir, Teed, Allison, te Riele, Hein, MacDonald, Marcy E.

Volltext

Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice von Gines, Silvia, Seong, Ihn Sik, Fossale, Elisa, Ivanova, Elena, Trettel, Flavia, Gusella, James F., Wheeler, Vanessa C., Persichetti, Francesca, MacDonald, Marcy E.

Volltext

Modification of the mouse mitochondrial genome by insertion of an exogenous gene von Wheeler, Vanessa C., Aitken, Mark, Coutelle, Charles

Volltext

Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum von Wheeler, Vanessa C, Lebel, Lori-Anne, Vrbanac, Vladimir, Teed, Allison, te Riele, Hein, MacDonald, Marcy E

Volltext

Nondegradative in Vitro Labeling of Plasmid DNA von Wheeler, V.C., Coutelle, C.

Volltext

Synthesis of a modified gene encoding human ornithine transcarbamylase for expression in mammalian mitochondrial and universal translation systems: a novel approach towards correct... von Wheeler, Vanessa C., Prodromou, Chrisostomos, Pearl, Laurence H., Williamson, Robert, Coutelle, Charles

Volltext

A11Induced pluripotent stem cells for basic and translational research on HD von Mattis, V B, Svendsen, S P, Ebert, A, Svendsen, C N, King, A R, Casale, M, Winokur, ST, Batugedara, G, Vawter, M, Donovan, P J, Lock, L F, Thompson, L M, Zhu, Y, Fossale, E, Atwal, R S, Gillis, T, Mysore, J, Li, J-h, Seong, I S, Shen, Y, Chen, X, Wheeler, V C, MacDonald, Marcy E, Gusella, J F, Akimov, S, Arbez, N, Juopperi, T, Ratovitski, T, Chiang, J H, Kim, W R, Chighladze, E, Watkin, E, Zhong, C, Makri, G, Cole, R N, Margolis, R L, Song, H, Ming, G, Ross, CA, Kaye, JA, Daub, A, Sharma, P, Mason, A R, Finkbeiner, S, Yu, J, Thomson, JA, Rushton, D, Brazier, S P, Battersby, A A, Redfern, A, et. al

Volltext

A Genome Scan for Modifiers of Age at Onset in Huntington Disease: The HD MAPS Study von Li, Jian-Liang, Hayden, Michael R., Almqvist, Elisabeth W., Brinkman, Ryan R., Durr, Alexandra, Dodé, Catherine, Morrison, Patrick J., Suchowersky, Oksana, Ross, Christopher A., Margolis, Russell L., Rosenblatt, Adam, Gómez-Tortosa, Estrella, Cabrero, David Mayo, Novelletto, Andrea, Frontali, Marina, Nance, Martha, Trent, Ronald J.A., McCusker, Elizabeth, Jones, Randi, Paulsen, Jane S., Harrison, Madeline, Zanko, Andrea, Abramson, Ruth K., Russ, Ana L., Knowlton, Beth, Djoussé, Luc, Mysore, Jayalakshmi S., Tariot, Suzanne, Gusella, Michael F., Wheeler, Vanessa C., Atwood, Larry D., Cupples, L. Adrienne, Saint-Hilaire, Marie, Cha, Jang-Ho J., Hersch, Steven M., Koroshetz, Walter J., Gusella, James F., MacDonald, Marcy E., Myers, Richard H.

Volltext

Introduction of plasmid DNA into isolated mitochondria by electroporation. A novel approach toward gene correction for mitochondrial disorders von Collombet, J M, Wheeler, V C, Vogel, F, Coutelle, C

Volltext

Mismatch repair gene Msh2 modifies the timing of early disease in Hdh super(Q111) striatum von Wheeler, V C, Lebel, L-A, Vrbanac, V, Teed, A, te Riele, H, MacDonald, ME

Volltext