Current advances in using neurotrophic factors to treat neurodegenerative disorders von Weissmiller, April M, Wu, Chengbiao

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Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration von Xu, Wei, Weissmiller, April M, White, 2nd, Joseph A, Fang, Fang, Wang, Xinyi, Wu, Yiwen, Pearn, Matthew L, Zhao, Xiaobei, Sawa, Mariko, Chen, Shengdi, Gunawardena, Shermali, Ding, Jianqing, Mobley, William C, Wu, Chengbiao

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Inhibition of MYC by the SMARCB1 tumor suppressor von Weissmiller, April M., Wang, Jing, Lorey, Shelly L., Howard, Gregory C., Martinez, Ernest, Liu, Qi, Tansey, William P.

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The MYC-WDR5 Nexus and Cancer von Thomas, Lance R, Foshage, Audra M, Weissmiller, April M, Tansey, William P

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MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor-1 von Popay, Tessa M, Wang, Jing, Adams, Clare M, Howard, Gregory Caleb, Codreanu, Simona G, Sherrod, Stacy D, McLean, John A, Thomas, Lance R, Lorey, Shelly L, Machida, Yuichi J, Weissmiller, April M, Eischen, Christine M, Liu, Qi, Tansey, William P

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Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus von Streeter, Sarah A, Williams, Alexandria G, Evans, James R, Wang, Jing, Guarnaccia, Alissa D, Florian, Andrea C, Al-Tobasei, Rafet, Liu, Qi, Tansey, William P, Weissmiller, April M

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Novel Autotaxin Inhibitor ATX-1d Significantly Enhances Potency of Paclitaxel-An In Silico and In Vitro Study von Rai, Prateek, Clark, Christopher J, Womack, Carl B, Dearing, Curtis, Thammathong, Joshua, Norman, Derek D, Tigyi, Gábor J, Sen, Subhabrata, Bicker, Kevin, Weissmiller, April M, Banerjee, Souvik

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Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity von Aho, Erin R., Wang, Jing, Gogliotti, Rocco D., Howard, Gregory C., Phan, Jason, Acharya, Pankaj, Macdonald, Jonathan D., Cheng, Ken, Lorey, Shelly L., Lu, Bin, Wenzel, Sabine, Foshage, Audra M., Alvarado, Joseph, Wang, Feng, Shaw, J. Grace, Zhao, Bin, Weissmiller, April M., Thomas, Lance R., Vakoc, Christopher R., Hall, Matthew D., Hiebert, Scott W., Liu, Qi, Stauffer, Shaun R., Fesik, Stephen W., Tansey, William P.

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WIN site inhibition disrupts a subset of WDR5 function von Siladi, Andrew J., Wang, Jing, Florian, Andrea C., Thomas, Lance R., Creighton, Joy H., Matlock, Brittany K., Flaherty, David K., Lorey, Shelly L., Howard, Gregory C., Fesik, Stephen W., Weissmiller, April M., Liu, Qi, Tansey, William P.

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Emerging Themes in Mechanisms of Tumorigenesis by SWI/SNF Subunit Mutation von Jones, Cheyenne A., Tansey, William P., Weissmiller, April M.

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Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport von Le, Michelle H, Weissmiller, April M, Monte, Louise, Lin, Po Han, Hexom, Tia C, Natera, Orlangie, Wu, Chengbiao, Rissman, Robert A

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A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP von Weissmiller, April M, Natera-Naranjo, Orlangie, Reyna, Sol M, Pearn, Matthew L, Zhao, Xiaobei, Nguyen, Phuong, Cheng, Soan, Goldstein, Lawrence S B, Tanzi, Rudolph E, Wagner, Steven L, Mobley, William C, Wu, Chengbiao

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Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells von Guarnaccia, Alissa D., Weissmiller, April M., Tansey, William P.

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WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines von Bumpous, Leigh A., Moe, Kylie C., Wang, Jing, Carver, Logan A., Williams, Alexandria G., Romer, Alexander S., Scobee, Jesse D., Maxwell, Jack N., Jones, Cheyenne A., Chung, Dai H., Tansey, William P., Liu, Qi, Weissmiller, April M.

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The SWI/SNF ATPase BRG1 facilitates multiple pro-tumorigenic gene expression programs in SMARCB1-deficient cancer cells von Moe, Kylie C., Maxwell, Jack N., Wang, Jing, Jones, Cheyenne A., Csaki, Grace T., Florian, Andrea C., Romer, Alexander S., Bryant, Daniel L., Farone, Anthony L., Liu, Qi, Tansey, William P., Weissmiller, April M.

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Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance von Thomas, Lance R., Adams, Clare M., Wang, Jing, Weissmiller, April M., Creighton, Joy, Lorey, Shelly L., Liu, Qi, Fesik, Stephen W., Eischen, Christine M., Tansey, William P.

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Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells von Florian, Andrea C, Woodley, Chase M, Wang, Jing, Grieb, Brian C, Slota, Macey J, Guerrazzi, Kiana, Hsu, Chih-Yuan, Matlock, Brittany K, Flaherty, David K, Lorey, Shelly L, Fesik, Stephen W, Howard, Gregory C, Liu, Qi, Weissmiller, April M, Tansey, William P

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WDR5 is a conserved regulator of protein synthesis gene expression von Bryan, Audra F, Wang, Jing, Howard, Gregory C, Guarnaccia, Alissa D, Woodley, Chase M, Aho, Erin R, Rellinger, Eric J, Matlock, Brittany K, Flaherty, David K, Lorey, Shelly L, Chung, Dai H, Fesik, Stephen W, Liu, Qi, Weissmiller, April M, Tansey, William P

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Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler von Woodley, Chase M., Romer, Alexander S., Wang, Jing, Guarnaccia, Alissa D., Elion, David L., Maxwell, Jack N., Guerrazzi, Kiana, McCann, Tyler S., Popay, Tessa M., Matlock, Brittany K., Flaherty, David K., Lorey, Shelly L., Liu, Qi, Tansey, William P., Weissmiller, April M.

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WD Repeat Domain 5 Inhibitors for Cancer Therapy: Not What You Think von Weissmiller, April M, Fesik, Stephen W, Tansey, William P

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