A Novel NAMPT Inhibitor-Based Antibody–Drug Conjugate Payload Class for Cancer Therapy von Böhnke, Niels, Berger, Markus, Griebenow, Nils, Rottmann, Antje, Erkelenz, Michael, Hammer, Stefanie, Berndt, Sandra, Günther, Judith, Wengner, Antje M., Stelte-Ludwig, Beatrix, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Jörißen, Hannah, Barak, Naomi, Bömer, Ulf, Hillig, Roman C., Eberspaecher, Uwe, Weiske, Jörg, Giese, Anja, Mumberg, Dominik, Nising, Carl Friedrich, Weinmann, Hilmar, Sommer, Anette

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Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2 von Eggert, Erik, Hillig, Roman C, Koehr, Silke, Stöckigt, Detlef, Weiske, Jörg, Barak, Naomi, Mowat, Jeffrey, Brumby, Thomas, Christ, Clara D, ter Laak, Antonius, Lang, Tina, Fernandez-Montalvan, Amaury E, Badock, Volker, Weinmann, Hilmar, Hartung, Ingo V, Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena, Kennedy, Steven, Li, Fengling, Vedadi, Masoud, Brown, Peter J, Santhakumar, Vijayaratnam, Arrowsmith, Cheryl H, Stellfeld, Timo, Stresemann, Carlo

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The Histidine Triad Protein Hint1 Triggers Apoptosis Independent of Its Enzymatic Activity von Weiske, Jörg, Huber, Otmar

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Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21 von Göricke, Fabian, Vu, Victoria, Smith, Leanna, Scheib, Ulrike, Böhm, Raphael, Akkilic, Namik, Wohlfahrt, Gerd, Weiske, Jörg, Bömer, Ulf, Brzezinka, Krzysztof, Lindner, Niels, Lienau, Philip, Gradl, Stefan, Beck, Hartmut, Brown, Peter J., Santhakumar, Vijayaratnam, Vedadi, Masoud, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Schmees, Norbert, Petersen, Kirstin

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Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target von Ellermann, Manuel, Eheim, Ashley, Rahm, Fredrik, Viklund, Jenny, Guenther, Judith, Andersson, Martin, Ericsson, Ulrika, Forsblom, Rickard, Ginman, Tobias, Lindström, Johan, Silvander, Camilla, Trésaugues, Lionel, Giese, Anja, Bunse, Stefanie, Neuhaus, Roland, Weiske, Jörg, Quanz, Maria, Glasauer, Andrea, Nowak-Reppel, Katrin, Bader, Benjamin, Irlbacher, Horst, Meyer, Hanna, Queisser, Nina, Bauser, Marcus, Haegebarth, Andrea, Gorjánácz, Mátyás

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Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A von Wortmann, Lars, Bräuer, Nico, Holton, Simon J, Irlbacher, Horst, Weiske, Jörg, Lechner, Christian, Meier, Robin, Karén, Jakob, Siöberg, Catrine Berthold, Pütter, Vera, Christ, Clara D, ter Laak, Antonius, Lienau, Philip, Lesche, Ralf, Nicke, Barbara, Cheung, Shing-Hu, Bauser, Marcus, Haegebarth, Andrea, von Nussbaum, Franz, Mumberg, Dominik, Lemos, Clara

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tumor suppressor Fhit acts as a repressor of β-catenin transcriptional activity von Weiske, Jörg, Albring, Kai Frederik, Huber, Otmar

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The specific fates of tight junction proteins in apoptotic epithelial cells von Bojarski, Christian, Weiske, Jörg, Schöneberg, Torsten, Schröder, Werner, Mankertz, Joachim, Schulzke, Jörg-Dieter, Florian, Peter, Fromm, Michael, Tauber, Rudolf, Huber, Otmar

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Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains von Bouché, Léa, Christ, Clara D, Siegel, Stephan, Fernández-Montalván, Amaury E, Holton, Simon J, Fedorov, Oleg, ter Laak, Antonius, Sugawara, Tatsuo, Stöckigt, Detlef, Tallant, Cynthia, Bennett, James, Monteiro, Octovia, Díaz-Sáez, Laura, Siejka, Paulina, Meier, Julia, Pütter, Vera, Weiske, Jörg, Müller, Susanne, Huber, Kilian V. M, Hartung, Ingo V, Haendler, Bernard

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The histidine triad protein Hint1 interacts with Pontin and Reptin and inhibits TCF-beta-catenin-mediated transcription von Weiske, Jörg, Huber, Otmar

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Wnt Signaling Inhibits Forkhead Box O3a-induced Transcription and Apoptosis through Up-regulation of Serum- and Glucocorticoid-inducible Kinase 1 von Dehner, Manuel, Hadjihannas, Michel, Weiske, Jörg, Huber, Otmar, Behrens, Jürgen

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Zona occludens-2 inhibits cyclin D1 expression and cell proliferation and exhibits changes in localization along the cell cycle von Tapia, Rocio, Huerta, Miriam, Islas, Socorro, Avila-Flores, Antonia, Lopez-Bayghen, Esther, Weiske, Jörg, Huber, Otmar, González-Mariscal, Lorenza

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Estrogen receptor alpha up-regulation and redistribution in human heart failure von Mahmoodzadeh, Shokoufeh, Eder, Sarah, Nordmeyer, Johannes, Ehler, Elisabeth, Huber, Otmar, Martus, Peter, Weiske, Jörg, Pregla, Reinhard, Hetzer, Roland, Regitz-Zagrosek, Vera

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Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A von Friberg, Anders, Rehwinkel, Hartmut, Duy Nguyen, Puetter, Vera, Quanz, Maria, Weiske, Joerg, Eberspaecher, Uwe, Heisler, Iring, Langer, Gernot

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β-catenin takes a HIT von Huber, Otmar, Weiske, Jörg

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Cleavage and Shedding of E-cadherin after Induction of Apoptosis von Steinhusen, Ulrike, Weiske, Jörg, Badock, Volker, Tauber, Rudolf, Bommert, Kurt, Huber, Otmar

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Key Role for Activin B in Cellular Transformation after Loss of the von Hippel-Lindau Tumor Suppressor von Wacker, Ingrid, Sachs, Martin, Knaup, Karl, Wiesener, Michael, Weiske, Jörg, Huber, Otmar, Akçetin, Ziya, Behrens, Jürgen

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Phorbol Ester Enhances KAI1 Transcription by Recruiting Tip60/Pontin Complexes von Rowe, Alexandra, Weiske, Jörg, Kramer, Tobias S., Huber, Otmar, Jackson, Paul

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Critical Evaluation of Native Electrospray Ionization Mass Spectrometry for Fragment‐Based Screening von Göth, Melanie, Badock, Volker, Weiske, Jörg, Pagel, Kevin, Kuropka, Benno

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Berberine acts as a natural inhibitor of Wnt/β-catenin signaling-Identification of more active 13-arylalkyl derivatives von Albring, Kai Frederik, Weidemüller, Julia, Mittag, Sonnhild, Weiske, Jörg, Friedrich, Karlheinz, Geroni, M. Cristina, Lombardi, Paolo, Huber, Otmar

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