Convergent, Regiospecific Synthesis of Quinolines from o-Aminophenylboronates von Horn, Joachim, Marsden, Stephen P, Nelson, Adam, House, David, Weingarten, Gordon G

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Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor von Liddle, John, Atkinson, Francis L., Barker, Michael D., Carter, Paul S., Curtis, Neil R., Davis, Rob P., Douault, Clement, Dickson, Marion C., Elwes, Dorothy, Garton, Neil S., Gray, Matthew, Hayhow, Thomas G., Hobbs, Clare I., Jones, Emma, Leach, Stuart, Leavens, Karen, Lewis, Huw D., McCleary, Scott, Neu, Margarete, Patel, Vipulkumar K., Preston, Alex G.S., Ramirez-Molina, Cesar, Shipley, Tracy J., Skone, Philip A., Smithers, Nick, Somers, Donald O., Walker, Ann L., Watson, Robert J., Weingarten, Gordon G.

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Synthesis and in vivo biological activity of large-ringed calixarenes against Mycobacterium tuberculosis von Goodworth, Kerry J., Hervé, Anne-Cécile, Stavropoulos, Evangelos, Hervé, Gwénaelle, Casades, Isabel, Hill, Alison M., Weingarten, Gordon G., Tascon, Ricardo E., Colston, M. Joseph, Hailes, Helen C.

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Nonsteroidal Glucocorticoid Agonists: Tetrahydronaphthalenes with Alternative Steroidal A-Ring Mimetics Possessing Dissociated (Transrepression/Transactivation) Efficacy Selectivit... von Biggadike, Keith, Boudjelal, Mohamed, Clackers, Margaret, Coe, Diane M, Demaine, Derek A, Hardy, George W, Humphreys, Davina, Inglis, Graham G. A, Johnston, Michael J, Jones, Haydn T, House, David, Loiseau, Richard, Needham, Deborah, Skone, Philip A, Uings, Iain, Veitch, Gemma, Weingarten, Gordon G, McLay, Iain M, Macdonald, Simon J. F

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Design and Synthesis of Pyrrolidine-5,5‘-trans-Lactams (5-Oxo-hexahydropyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 4. Antiviral A... von Borthwick, Alan D, Davies, Dave E, Ertl, Peter F, Exall, Anne M, Haley, Terry M, Hart, Graham J, Jackson, Deborah L, Parry, Nigel R, Patikis, Angela, Trivedi, Naimisha, Weingarten, Gordon G, Woolven, James M

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Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists von Barnett, Heather A., Coe, Diane M., Cooper, Tony W.J., Jack, Torquil I., Jones, Haydn T., Macdonald, Simon J.F., McLay, Iain M., Rayner, Natalie, Sasse, Rosemary Z., Shipley, Tracy J., Skone, Phil A., Somers, Graham I., Taylor, Simon, Uings, Iain J., Woolven, James M., Weingarten, Gordon G.

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Design and Synthesis of Pyrrolidine-5,5-trans-lactams (5-Oxohexahydropyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 2. Potency and C... von Borthwick, Alan D, Crame, Andrew J, Ertl, Peter F, Exall, Anne M, Haley, Terry M, Hart, Graham J, Mason, Andrew M, Pennell, Andrew M. K, Singh, Onkar M. P, Weingarten, Gordon G, Woolven, James M

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Design and Synthesis of Pyrrolidine-5,5-trans-lactams (5-Oxo-hexahydro-pyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 1. The α-Methy... von Borthwick, Alan D, Angier, S. Jane, Crame, Andrew J, Exall, Anne M, Haley, Terry M, Hart, Graham J, Mason, Andrew M, Pennell, Andrew M. K, Weingarten, Gordon G

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Identification of potent and selective oxytocin antagonists. Part 2: further investigation of benzofuran derivatives von Wyatt, Paul G., Allen, Michael J., Chilcott, Josie, Gardner, Christopher J., Livermore, David G., Mordaunt, Jackie E., Nerozzi, Fabrizio, Patel, Mamta, Perren, Marion J., Weingarten, Gordon G., Shabbir, Shalia, Woollard, Patrick M., Zhou, Ping

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Pyrrolidine-5,5- trans-lactams as novel mechanism-based inhibitors of human cytomegalovirus protease. Part 3: potency and plasma stability von Borthwick, Alan D, Exall, Anne M, Haley, Terry M, Jackson, Deborah L, Mason, Andrew M, Weingarten, Gordon G

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Convergent synthesis of dihydroquinolones from o-aminoarylboronates von Horn, Joachim, Li, Ho Yin, Marsden, Stephen P., Nelson, Adam, Shearer, Rachel J., Campbell, Amanda J., House, David, Weingarten, Gordon G.

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The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist von MADAUSS, Kevin P, BLEDSOE, Randy K, MCLAY, Iain, STEWART, Eugene L, UINGS, Iain J, WEINGARTEN, Gordon, WILLIAMS, Shawn P

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Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase von Humber, David C, Cammack, Nicholas, Coates, Jonathan A. V, Cobley, Kevin N, Orr, David C, Storer, Richard, Weingarten, Gordon G, Weir, Malcolm P

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Design and synthesis of monocyclic β-lactams as mechanism-based inhibitors of human cytomegalovirus protease von Borthwick, Alan D., Weingarten, Gordon, Haley, Terry M., Tomaszewski, Mirek, Wang, Wei, Hu, Zhouhan, Bedard, Jean, Jin, Haloun, Yuen, Leonard, Mansour, Tarek S.

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Efficient synthesis of an α-trifluoromethyl-α-tosyloxymethyl epoxide enabling stepwise double functionalisation to afford CF3-substituted tertiary alcohols von Keeling, Steven P., Campbell, Ian B., Coe, Diane M., Cooper, Tony W.J., Hardy, George W., Jack, Torquil I., Jones, Haydn T., Needham, Deborah, Shipley, Tracy J., Skone, Philip A., Sutton, Peter W., Weingarten, Gordon A., Macdonald, Simon J.F.

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Convergent synthesis of dihydroquinolones from o-aminoarylboronates: Modern Applications of Transition Metal Catalysis in Heterocycle Synthesis von HORN, Joachim, HO YIN LI, MARSDEN, Stephen P, NELSON, Adam, SHEARER, Rachel J, CAMPBELL, Amanda J, HOUSE, David, WEINGARTEN, Gordon G

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An efficient synthesis of a chiral carbocyclic 2′-deoxyribonucleoside synthon by directed reduction von Borthwick, Alan D., Crame, Andrew J., Exall, Anne M., Weingarten, Gordon G.

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Efficient synthesis of an α-trifluoromethyl-α-tosyloxymethyl epoxide enabling stepwise double functionalisation to afford CF 3-substituted tertiary alcohols von Keeling, Steven P., Campbell, Ian B., Coe, Diane M., Cooper, Tony W.J., Hardy, George W., Jack, Torquil I., Jones, Haydn T., Needham, Deborah, Shipley, Tracy J., Skone, Philip A., Sutton, Peter W., Weingarten, Gordon A., Macdonald, Simon J.F.

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Predictive models for the overall 5- endo-trig iodocyclisation of homoallylic alcohols von Barks, Jenny M., Knight, David W., Seaman, Christopher J., Weingarten, Gordon G.

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Synthesis from (-)-aristeromycin and X-ray structure of (-)-carbovir von EXALL, A. M, JONES, M. F, COOK, J, LAKE, D. E, MEERHOLZ, C. A, TURNBULL, P. J, HIGHCOCK, R. M, CHI-LEUNG MO, MYERS, P. L, PATERNOSTER, I. L, SINGH, H, STORER, R, WEINGARTEN, G. G, WILLIAMSON, C, BRODIE, A. C

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