Structure-Based Design of an Osteoclast-Selective, Nonpeptide Src Homology 2 Inhibitor with in vivo Antiresorptive Activity von Shakespeare, William, Yang, Michael, Bohacek, Regine, Cerasoli, Franklin, Stebbins, Karin, Sundaramoorthi, Raji, Azimioara, Mihai, Vu, Chi, Pradeepan, Selvi, Metcalf, Chester, Haraldson, Chad, Merry, Taylor, Dalgarno, David, Narula, Surinder, Hatada, Marcos, Lu, Xiaode, van Schravendijk, Marie Rose, Adams, Susan, Violette, Shelia, Smith, Jeremy, Guan, Wei, Bartlett, Catherine, Herson, Jay, Iuliucci, John, Weigele, Manfred, Sawyer, Tomi

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Bone-Targeted 2,6,9-Trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases von Wang, Yihan, Metcalf, Chester A., Shakespeare, William C., Sundaramoorthi, Raji, Keenan, Terence P., Bohacek, Regine S., van Schravendijk, Marie Rose, Violette, Shiela M., Narula, Surinder S., Dalgarno, David C., Haraldson, Chad, Keats, Jeffrey, Liou, Shuenn, Mani, Ukti, Pradeepan, Selvi, Ram, Mary, Adams, Susan, Weigele, Manfred, Sawyer, Tomi K.

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Novel Protein Kinase Inhibitors: SMART Drug Design Technology von Sawyer, Tomi K, Bohacek, Regine S, III, Chester A. Metcalf, Shakespeare, William C, Wang, Yihan, Sundaramoorthi, Raji, Keenan, Terence, Narula, Surinder, Weigele, Manfred, Dalgarno, David C

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Regulation of Physiologic Actions of LRRK2: Focus on Autophagy von Ferree, Andrew, Guillily, Maria, Li, Hu, Smith, Katelyn, Takashima, Aki, Squillace, Rachel, Weigele, Manfred, Collins, James J., Wolozin, Benjamin

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Selective Inhibition of Src SH2 by a Novel Thiol-Targeting Tricarbonyl-Modified Inhibitor and Mechanistic Analysis by 1H/ 13C NMR Spectroscopy von Sundaramoorthi, Raji, Siedem, Chris, Vu, Chi B, Dalgarno, David C, Laird, Ellen C, Botfield, Martyn C, Combs, Amanda B, Adams, Susan E, Yuan, Ruth W, Weigele, Manfred, Narula, Surinder S

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Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine-based Compounds von Dalgarno, David, Stehle, Thilo, Narula, Surinder, Schelling, Pierre, Rose van Schravendijk, Marie, Adams, Susan, Andrade, Lawrence, Keats, Jeff, Ram, Mary, Jin, Lei, Grossman, Trudy, MacNeil, Ian, Metcalf III, Chester, Shakespeare, William, Wang, Yihan, Keenan, Terry, Sundaramoorthi, Raji, Bohacek, Regine, Weigele, Manfred, Sawyer, Tomi

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Synthesis of iso-ddA, member of a novel class of anti-HIV agents von Huryn, Donna M., Sluboski, Barbara C., Tam, Steve Y., Todaro, Louis J., Weigele, Manfred

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Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range von Udenfriend, Sidney, Stein, Stanley, Böhlen, Peter, Dairman, Wallace, Leimgruber, Willy, Weigele, Manfred

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Synthesis of (S)-manoalide diol and the absolute configuration of natural manoalide von Amoo, Victor Ekow, De Bernardo, Silvano, Weigele, Manfred

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SAR of Carbon-Linked, 2-Substituted Purines: Synthesis and Characterization of AP23451 as a novel Bone-Targeted Inhibitor of Src Tyrosine Kinase With In Vivo Anti-Resorptive Activi... von Shakespeare, William C, Wang, Yihan, Bohacek, Regine, Keenan, Terry, Sundaramoorthi, Raji, Metcalf, Chet III, Dilauro, Anne, Roeloffzen, Sonya, Liu, Shuangying, Saltmarsh, Jennifer, Paramanathan, Guru, Dalgarno, David, Narula, Surinder, Pradeepan, Selvi, van Schravendijk, Marie Rose, Keats, Jeff, Ram, Mary, Liou, Shuenn, Adams, Susan, Wardwell, Scott, Bogus, Julie, Iuliucci, John, Weigele, Manfred, Xing, Lianping, Boyce, Brendan, Sawyer, Tomi K

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Bone-Targeted Src kinase inhibitors: novel pyrrolo- and pyrazolopyrimidine analogues von Sundaramoorthi, Raji, Shakespeare, William C., Keenan, Terence P., Metcalf, Chester A., Wang, Yihan, Mani, Ukti, Taylor, Merry, Liu, Shuangying, Bohacek, Regine S., Narula, Surinder S., Dalgarno, David C., Van Schravandijk, Marie Rose, Violette, Sheila M., Liou, Shuenn, Adams, Susan, Ram, Mary K., Keats, Jeffrey A., Weigele, Manfred, Sawyer, Tomi K.

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X-ray Structure of Citrate Bound to Src SH2 Leads to a High-Affinity, Bone-Targeted Src SH2 Inhibitor von Bohacek, Regine S, Dalgarno, David C, Hatada, Marcos, Jacobsen, Virginia A, Lynch, Berkley A, Macek, Karina J, Merry, Taylor, Metcalf, Chester A, Narula, Surinder S, Sawyer, Tomi K, Shakespeare, William C, Violette, Shelia M, Weigele, Manfred

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Isolation and Identification of "Diazepam-Like" Compounds From Bovine Urine von Luk, Kin-Chun, Stern, Lorraine, Weigele, Manfred, O'Brien, Robert A, Spirt, Nena

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Bone-Targeted pyrido[2,3- d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents von Vu, Chi B., Luke, George P., Kawahata, Noriyuki, Shakespeare, William C., Wang, Yihan, Sundaramoorthi, Raji, Metcalf, Chester A., Keenan, Terence P., Pradeepan, Selvi, Corpuz, Evelyn, Merry, Taylor, Bohacek, Regine S., Dalgarno, David C., Narula, Surinder S., van Schravendijk, Marie Rose, Ram, Mary K., Adams, Susan, Liou, Shuenn, Keats, Jeffrey A., Violette, Shelia M., Guan, Wei, Weigele, Manfred, Sawyer, Tomi K.

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THE SYNTHESIS AND BIOLOGICAL TESTING OF 2, 2-DIMETHYLPENAM SULFONE von FOLEY, LOUISE H., WEIGELE, MANFRED

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Selective inhibition of Src SH2 by a novel thiol-targeting tricarbonyl-modified inhibitor and mechanistic analysis by (1)H/(13)C NMR spectroscopy von Sundaramoorthi, R, Siedem, C, Vu, C B, Dalgarno, D C, Laird, E C, Botfield, M C, Combs, A B, Adams, S E, Yuan, R W, Weigele, M, Narula, S S

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Research Article: Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine-based Compounds von Dalgarno, David, Stehle, Thilo, Narula, Surinder, Schelling, Pierre, Rose van Schravendijk, Marie, Adams, Susan, Andrade, Lawrence, Keats, Jeff, Ram, Mary, Jin, Lei, Grossman, Trudy, MacNeil, Ian, Metcalf, Chester, Shakespeare, William, Wang, Yihan, Keenan, Terry, Sundaramoorthi, Raji, Bohacek, Regine, Weigele, Manfred, Sawyer, Tomi

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Novel protein kinase inhibitors: SMART drug design technology von SAWYER, Tomi K, BOHACEK, Regine S, METCALF, Chester A, SHAKESPEARE, William C, YIHAN WANG, SUNDARAMOORTHI, Raji, KEENAN, Terence, NARULA, Surinder, WEIGELE, Manfred, DALGARNO, David C

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COMPOUNDS, COMPOSITIONS AND METHODS OF USE von Larsen Glenn R, Vacca Joseph P, Weigele Manfred

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COMPOUNDS, COMPOSITIONS AND METHODS OF USE von Larsen Glenn R, Vacca Joseph P, Weigele Manfred

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