Characterization of an alternative BAK-binding site for BH3 peptides von Ye, Kaiqin, Meng, Wei X., Sun, Hongbin, Wu, Bo, Chen, Meng, Pang, Yuan-Ping, Gao, Jia, Wang, Hongzhi, Wang, Junfeng, Kaufmann, Scott H., Dai, Haiming

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Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells von Schroeder, Barbara, Vander Steen, Travis, Espinoza, Ingrid, Venkatapoorna, Chandra M. Kurapaty, Hu, Zeng, Silva, Fernando Martín, Regan, Kevin, Cuyàs, Elisabet, Meng, X. Wei, Verdura, Sara, Arbusà, Aina, Schneider, Paula A., Flatten, Karen S., Kemble, George, Montero, Joan, Kaufmann, Scott H., Menendez, Javier A., Lupu, Ruth

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Contribution of Bcl-2 Phosphorylation to Bak Binding and Drug Resistance von HAIMING DAI, HUSHENG DING, WEI MENG, X, LEE, Sun-Hee, SCHNEIDER, Paula A, KAUFMANN, Scott H

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Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization von Dai, Haiming, Smith, Alyson, Meng, X Wei, Schneider, Paula A, Pang, Yuan-Ping, Kaufmann, Scott H

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ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance von O’Sullivan, Julia, Kothari, Charu, Caron, Marie-Christine, Gagné, Jean-Philippe, Jin, Zhigang, Nonfoux, Louis, Beneyton, Adèle, Coulombe, Yan, Thomas, Mélissa, Atalay, Nurgul, Meng, X Wei, Milano, Larissa, Jean, Dominique, Boisvert, François-Michel, Kaufmann, Scott H, Hendzel, Michael J, Masson, Jean-Yves, Poirier, Guy G

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Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells von Dai, Haiming, Ding, Husheng, Meng, X Wei, Peterson, Kevin L, Schneider, Paula A, Karp, Judith E, Kaufmann, Scott H

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CDK2-Mediated Upregulation of TNF alpha as a Mechanism of Selective Cytotoxicity in Acute Leukemia von Ding, Husheng, Vincelette, Nicole D., McGehee, Cordelia D., Kohorst, Mira A., Koh, Brian D., Venkatachalam, Annapoorna, Meng, X. Wei, Schneider, Paula A., Flatten, Karen S., Peterson, Kevin L., Correia, Cristina, Lee, Sun-Hee, Patnaik, Mrinal, Webster, Jonathan A., Ghiaur, Gabriel, Smith, B. Douglas, Karp, Judith E., Pratz, Keith W., Li, Hu, Karnitz, Larry M., Kaufmann, Scott H.

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Death Receptor 5 Signaling Promotes Hepatocyte Lipoapoptosis von Cazanave, Sophie C., Mott, Justin L., Bronk, Steven F., Werneburg, Nathan W., Fingas, Christian D., Meng, X. Wei, Finnberg, Niklas, El-Deiry, Wafik S., Kaufmann, Scott H., Gores, Gregory J.

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Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors von Venkatachalam, Annapoorna, Correia, Cristina, Peterson, Kevin L, Hou, Xianon, Schneider, Paula A, Strathman, Annabella R, Flatten, Karen S, Sine, Chance C, Balczewski, Emily A, McGehee, Cordelia D, Larson, Melissa C, Duffield, Laura N, Meng, X Wei, Vincelette, Nicole D, Ding, Husheng, Oberg, Ann L, Couch, Fergus J, Swisher, Elizabeth M, Li, Hu, Weroha, S John, Kaufmann, Scott H

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Mitochondrial apoptosis and BH3 mimetics [version 1; peer review: 3 approved] von Dai, Haiming, Meng, X. Wei, Kaufmann, Scott H

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Cytotoxicity of farnesyltransferase inhibitors in lymphoid cells mediated by MAPK pathway inhibition and Bim up-regulation von Ding, Husheng, Hackbarth, Jennifer, Schneider, Paula A., Peterson, Kevin L., Meng, X. Wei, Dai, Haiming, Witzig, Thomas E., Kaufmann, Scott H.

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Characterization of a RAD51C -silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance von Hurley, Rachel M, McGehee, Cordelia D, Nesic, Ksenija, Correia, Cristina, Weiskittel, Taylor M, Kelly, Rebecca L, Venkatachalam, Annapoorna, Hou, Xiaonan, Pathoulas, Nicholas M, Meng, X Wei, Kondrashova, Olga, Radke, Marc R, Schneider, Paula A, Flatten, Karen S, Peterson, Kevin L, Becker, Marc A, Wong, Ee Ming, Southey, Melissa S, Dobrovic, Alexander, Lin, Kevin K, Harding, Thomas C, McNeish, Iain, Ross, Christian A, Wagner, Jill M, Wakefield, Matthew J, Scott, Clare L, Haluska, Paul, Wahner Hendrickson, Andrea E, Karnitz, Larry M, Swisher, Elizabeth M, Li, Hu, Weroha, S John, Kaufmann, Scott H

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Context-dependent Bcl-2/Bak Interactions Regulate Lymphoid Cell Apoptosis von Dai, Haiming, Meng, X. Wei, Lee, Sun-Hee, Schneider, Paula A., Kaufmann, Scott H.

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Selective Inhibition of BFL1: It’s All about Finding the Right Partner von Dai, Haiming, Meng, X. Wei, Kaufmann, Scott H.

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A BAK subdomain that binds mitochondrial lipids selectively and releases cytochrome C von Dai, Haiming, Peterson, Kevin L., Flatten, Karen S., Meng, X. Wei, Venkatachalam, Annapoorna, Correia, Cristina, Ramirez-Alvarado, Marina, Pang, Yuan-Ping, Kaufmann, Scott H.

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BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma von Correia, Cristina, Schneider, Paula A., Dai, Haiming, Dogan, Ahmet, Maurer, Matthew J., Church, Amy K., Novak, Anne J., Feldman, Andrew L., Wu, Xiaosheng, Ding, Husheng, Meng, X. Wei, Cerhan, James R., Slager, Susan L., Macon, William R., Habermann, Thomas M., Karp, Judith E., Gore, Steven D., Kay, Neil E., Jelinek, Diane F., Witzig, Thomas E., Nowakowski, Grzegorz S., Kaufmann, Scott H.

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53BP1 as a potential predictor of response in PARP inhibitor-treated homologous recombination-deficient ovarian cancer von Hurley, Rachel M., Wahner Hendrickson, Andrea E., Visscher, Daniel W., Ansell, Peter, Harrell, Maria I., Wagner, Jill M., Negron, Vivian, Goergen, Krista M., Maurer, Matthew J., Oberg, Ann L., Meng, X. Wei, Flatten, Karen S., De Jonge, Maja J.A., Van Herpen, Carla D., Gietema, Jourik A., Koornstra, Rutger H.T., Jager, Agnes, den Hollander, Martha W., Dudley, Matthew, Shepherd, Stacie P., Swisher, Elizabeth M., Kaufmann, Scott H.

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AMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell death von Jia, Jia, Ji, Wenbo, Saliba, Antoine N., Csizmar, Clifford M., Ye, Kaiqin, Hu, Lei, Peterson, Kevin L., Schneider, Paula A., Meng, X. Wei, Venkatachalam, Annapoorna, Patnaik, Mrinal M., Webster, Jonathan A., Smith, B. Douglas, Ghiaur, Gabriel, Wu, Xinyan, Zhong, Jun, Pandey, Akhilesh, Flatten, Karen S., Deng, Qingmei, Wang, Hongzhi, Kaufmann, Scott H., Dai, Haiming

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Measurement of BH3-only protein tolerance von Dai, Haiming, Ding, Husheng, Peterson, Kevin L, Meng, X Wei, Schneider, Paula A, Knorr, Katherine L B, Kaufmann, Scott H

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Poly(ADP-ribose) Polymerase Inhibitors Sensitize Cancer Cells to Death Receptor-mediated Apoptosis by Enhancing Death Receptor Expression von Meng, X.Wei, Koh, Brian D., Zhang, Jin-San, Flatten, Karen S., Schneider, Paula A., Billadeau, Daniel D., Hess, Allan D., Smith, B.Douglas, Karp, Judith E., Kaufmann, Scott H.

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