Histone Deacetylase 8 in Neuroblastoma Tumorigenesis von Oehme, Ina, Deubzer, Hedwig E, Wegener, Dennis, Pickert, Diana, Linke, Jan-Peter, Hero, Barbara, Kopp-Schneider, Annette, Westermann, Frank, Ulrich, Scott M, von Deimling, Andreas, Fischer, Matthias, Witt, Olaf

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Improved fluorogenic histone deacetylase assay for high-throughput-screening applications von Wegener, Dennis, Hildmann, Christian, Riester, Daniel, Schwienhorst, Andreas

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Directed Evolution of a (β α )8-barrel Enzyme to Catalyze Related Reactions in Two Different Metabolic Pathways von Jürgens, C, Strom, A, Wegener, D, Hettwer, S, Wilmanns, M, Sterner, R

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Max Siller, ed. Hans Vintler: Die Blumen der Tugend (1411). Symposium nach 600 Jahren, Schlern-Schriften, Band 362. Innsbruck: Universitätsverlag Wagner, 2015. Pp. 428 von Wegener, Dennis

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Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases von Hildmann, Christian, Wegener, Dennis, Riester, Daniel, Hempel, René, Schober, Andreas, Merana, Joachim, Giurato, Laura, Guccione, Salvatore, Nielsen, Tine Kragh, Ficner, Ralf, Schwienhorst, Andreas

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Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction von Hillig, Roman C., Sautier, Brice, Schroeder, Jens, Moosmayer, Dieter, Hilpmann, André, Stegmanna, Christian M., Werbeck, Nicolas D., Briem, Hans, Boemer, Ulf, Weiske, Joerg, Badock, Volker, Mastouri, Julia, Petersen, Kirstin, Siemeister, Gerhard, Kahmann, Jan D., Wegener, Dennis, Böhnke, Niels, Eis, Knut, Graham, Keith, Wortmann, Lars, von Nussbaum, Franz, Bader, Benjamin

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Addressing a New Paradigm Shift in Data Science: An Empirical Study on Novel Project Characteristics for Foundation Model Projects von Giesselbach, Sven, Wegener, Dennis, Helmer, Lennard, Martens, Claudio, Ruping, Stefan

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A New Amidohydrolase from Bordetella or Alcaligenes Strain FB188 with Similarities to Histone Deacetylases von HILDMANN, Christian, NINKOVIC, Milena, DIETRICH, Rüdiger, WEGENER, Dennis, RIESTER, Daniel, ZIMMERMANN, Thomas, BIRCH, Olwen M, BERNEGGER, Christine, LOIDL, Peter, SCHWIENHORST, Andreas

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Grid-enabling data mining applications with DataMiningGrid: An architectural perspective von Stankovski, Vlado, Swain, Martin, Kravtsov, Valentin, Niessen, Thomas, Wegener, Dennis, Kindermann, Jörg, Dubitzky, Werner

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Members of the histone deacetylase superfamily differ in substrate specificity towards small synthetic substrates von Riester, Daniel, Wegener, Dennis, Hildmann, Christian, Schwienhorst, Andreas

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Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes von Wigle, Tim J., Church, W. David, Majer, Christina R., Swinger, Kerren K., Aybar, Demet, Schenkel, Laurie B., Vasbinder, Melissa M., Brendes, Arne, Beck, Claudia, Prahm, Martin, Wegener, Dennis, Chang, Paul, Kuntz, Kevin W.

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A Fluorogenic Histone Deacetylase Assay Well Suited for High-Throughput Activity Screening von Wegener, Dennis, Wirsching, Frank, Riester, Daniel, Schwienhorst, Andreas

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GridR: An R-based tool for scientific data analysis in grid environments von Wegener, Dennis, Sengstag, Thierry, Sfakianakis, Stelios, Rüping, Stefan, Assi, Anthony

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HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells von Wegener, Dennis, Deubzer, Hedwig E, Oehme, Ina, Milde, Till, Hildmann, Christian, Schwienhorst, Andreas, Witt, Olaf

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Digging Deep into the Data Mine with DataMiningGrid von Stankovski, V., Swain, M., Kravtsov, V., Niessen, T., Wegener, D., Rohm, M., Trnkoczy, J., May, M., Franke, J., Schuster, A., Dubitzky, W.

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An active site tyrosine residue is essential for amidohydrolase but not for esterase activity of a class 2 histone deacetylase-like bacterial enzyme von Moreth, Kristin, Riester, Daniel, Hildmann, Christian, Hempel, René, Wegener, Dennis, Schober, Andreas, Schwienhorst, Andreas

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Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay von Wegener, Dennis, Hildmann, Christian, Riester, Daniel, Schober, Andreas, Meyer-Almes, Franz-Josef, Deubzer, Hedwig E, Oehme, Ina, Witt, Olaf, Lang, Siegmund, Jaensch, Martina, Makarov, Vadim, Lange, Corinna, Busse, Benedikt, Schwienhorst, Andreas

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Robotic alliance of miniaturized synthesis and screening: A case study for the identification of histone deacetylase inhibitors von Groß, G. Alexander, Singh, Sukhdeep, Schlingloff, Gregor, Schwienhorst, Andreas, Riester, Daniel, Wegener, Dennis, Wurziger, Hanns, Schober, Andreas

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Recent progress in the development of assays suited for histone deacetylase inhibitor screening von Wegener, Dennis, Hildmann, Christian, Schwienhorst, Andreas

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The ACGT project in retrospect: Lessons learned and future outlook von Bucur, Anca, Ruping, Stefan, Sengstag, Thierry, Sfakianakis, Stelios, Tsiknakis, Manolis, Wegener, Dennis

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