Effectors of Escherichia coli aspartate transcarbamoylase differentially perturb aspartate binding rather than the T-R transition von Hsuanyu, Y C, Wedler, F C

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Kinetic mechanism of native Escherichia coli aspartate transcarbamylase von Hsuanyu, Yuchiong, Wedler, Frederick C.

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Manganese(II) dynamics and distribution in glial cells cultured from chick cerebral cortex von WEDLER, F. C, LEY, B. W, GRIPPO, A. A

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Threonine Synthase of Escherichia coli: Inhibition by Classical and Slow-Binding Analogues of Homoserine Phosphate von Farrington, G.K., Kumar, A., Shames, S.L., Ewaskiewicz, J.I., Ash, D.E., Wedler, F.C.

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Effects of Ca(II) ions on Mn(II) dynamics in chick glia and rat astrocytes : potential regulation of glutamine synthetase von WEDLER, F. C, VICHNIN, M. C, LEY, B. W, THOLEY, G, LEDIG, M, COPIN, J.-C

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Design and synthesis of phosphonate inhibitors of glutamine synthetase von Farrington, G. King, Kumar, Alok, Wedler, Frederick C

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Site-specific mutation of Tyr240----Phe in the catalytic chain of Escherichia coli aspartate transcarbamylase. Consequences for kinetic mechanism von YUCHIONG HSUANYU, WEDLER, F. C, KANTROWITZ, E. R, MIDDLETON, S. A

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Regulatory Behavior of Escherichia coli Aspartate Transcarbamylase Altered by Site-specific Mutation of Tyr240 → Phe in the Catalytic Chain von Wedler, F C, Hsuanyu, Y C, Kantrowitz, E R, Middleton, S A

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Modulation of Mn2+ accumulation in cultured rat neuronal and astroglial cells von THOLEY, G, MEGIAS-MEGIAS, L, WEDLER, F. C, LEDIG, M

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Interaction of aspartate and aspartate-derived antimetabolites with the enzymes of the threonine biosynthetic pathway of Escherichia coli von Shames, S L, Ash, D E, Wedler, F C, Villafranca, J J

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Analysis of Ter-Ter enzyme kinetic mechanisms by computer simulation of isotope exchange at chemical equilibrium: Development and application of ISOTER, a personal-computer-based p... von Wedler, Frederick C., Barkley, Robert W.

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Catalytic mechanisms of glutamine synthetase enzymes. studies with analogs of possible intermediates and transition states von Wedler, F.C, Horn, B.R

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On the binding of L-S- and L-R-diastereoisomers of the substrate analog L-methionine sulfoximine to glutamine synthetase from Escherichia coli von Shrake, A, Ginsburg, A, Wedler, F C, Sugiyama, Y

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Glutamine synthetase of Bacillus stearothermophilus. Regulation, site interactions, and functional information von Wedler, F. C, Carfi, J, Ashour, A. E

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Phosphate and carbonate ester aging reactions with .alpha.-chymotrypsin. Kinetics and mechanism von Bender, M. L, Wedler, F. C

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Evidence for methionine sulfoximine as a transition-state analog for glutamine synthetase from NMR and EPR data von Villafranca, J.J., Ash, D.E., Wedler, F.C.

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Glutamine synthetase from ovine brain is a manganese(II) enzyme von Wedler, Frederick C, Denman, Robert B, Roby, W. Gary

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Association-dissociation of mammalian brain glutamine synthetase: Effects of metal ions and other ligands von Denman, Robert B., Wedler, Frederick C.

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[17] Equilibrium isotope exchange in enzyme catalysis von Wedler, Frederick C.

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PH-dependent proton absorption in chymotrypsin binding. Evidence for a pH-dependent conformation change of the enzyme von Bender, Myron L, Wedler, Frederick C

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