SP0190 Juvenile Dermatomyositis: Whats New in 2014? von Wedderburn, L.

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Expression of myxovirus‐resistance protein A: a possible marker of muscle disease activity and autoantibody specificities in juvenile dermatomyositis von Soponkanaporn, S., Deakin, C. T., Schutz, P. W., Marshall, L. R., Yasin, S. A., Johnson, C. M., Sag, E., Tansley, S. L., McHugh, N. J., Wedderburn, L. R., Jacques, T. S.

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Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases von Hinks, A, Bowes, J, Cobb, J, Ainsworth, HC, Marion, MC, Comeau, ME, Sudman, M, Han, B, Becker, ML, Bohnsack, JF, de Bakker, PIW, Haas, JP, Hazen, M, Lovell, DJ, Nigrovic, PA, Nordal, Ellen Berit, Punnaro, M, Rosenberg, AM, Rygg, Marite, Smith, S.L, Wise, CA, Videm, Vibeke, Wedderburn, LR, Yarwood, A, Yeung, RSM, Prahalad, S, Langefeld, CD, Raychaudhuri, S, Thompson, SD, Thomson, W

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Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes von Miller, F W, Chen, W, O'Hanlon, T P, Cooper, R G, Vencovsky, J, Rider, L G, Danko, K, Wedderburn, L R, Lundberg, I E, Pachman, L M, Reed, A M, Ytterberg, S R, Padyukov, L, Selva-O'Callaghan, A, Radstake, T R, Isenberg, D A, Chinoy, H, Ollier, W E R, Scheet, P, Peng, B, Lee, A, Byun, J, Lamb, J A, Gregersen, P K, Amos, C I

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Juvenile Dermatomyositis: what comes next? Long-term outcomes in childhood myositis from a patient perspective von Boros, C., McCann, L., Simou, S., Cancemi, D., Ambrose, N., Pilkington, C. A., Cortina-Borja, M., Wedderburn, L. R

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The Juvenile Dermatomyositis National Registry and Repository (UK and Ireland) : clinical characteristics of children recruited within the first 5 yr von MCCANN, L. J, JUGGINS, A. D, MAILLARD, S. M, WEDDERBURN, L. R, DAVIDSON, J. E, MURRAY, K. J, PILKINGTON, C. A

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Clinical associations of autoantibodies to a p155/140 kDa doublet protein in juvenile dermatomyositis von Gunawardena, H., Wedderburn, L. R., North, J., Betteridge, Z., Dunphy, J., Chinoy, H., Davidson, J. E., Cooper, R. G., McHugh, N. J.

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Development and External Validation of a Model Predicting New‐Onset Chronic Uveitis at Different Disease Durations in Juvenile Idiopathic Arthritis von Straalen, Joeri W., Kearsley‐Fleet, Lianne, Klotsche, Jens, Roock, Sytze, Minden, Kirsten, Heiligenhaus, Arnd, Hyrich, Kimme L., Boer, Joke H., Lamot, Lovro, Olivieri, Alma N., Gallizzi, Romina, Smolewska, Elzbieta, Faugier, Enrique, Pastore, Serena, Hashkes, Philip J., Herrera, Cristina N., Emminger, Wolfgang, Consolini, Rita, Wulffraat, Nico M., Ruperto, Nicolino, Swart, Joost F., Cleary, G, Baildam, E, Wedderburn, L, Davidson, J, Chieng, A, McErlane, F, Foster, H, Ciurtin, C, Ioannou, Y, Thomson, W, Hyrich, K, Kallinich, Tilmann, Dressler, Frank, Deschner, Jasmin Kümmerle, Weller‐Heinemann, Frank, Horneff, Gerd, Hospach, Anton, Mönkemöller, Kirsten, Haas, Johannes Peter, Windschall, Daniel, Foeldvari, Ivan, Foell, Dirk

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Comparison of children with onset of juvenile dermatomyositis symptoms before or after their fifth birthday in a UK and Ireland juvenile dermatomyositis cohort study von Martin, N., Krol, P., Smith, S., Beard, L., Pilkington, C. A., Davidson, J., Wedderburn, L. R.

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Autologous stem cell transplantation for refractory juvenile idiopathic arthritis: analysis of clinical effects, mortality, and transplant related morbidity von de Kleer, I M, Brinkman, D M C, Ferster, A, Abinun, M, Quartier, P, van der Net, J, ten Cate, R, Wedderburn, L R, Horneff, G, Oppermann, J, Zintl, F, Foster, H E, Prieur, A M, Fasth, A, van Rossum, M A J, Kuis, W, Wulffraat, N M

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Genotyping of immune-related genetic variants identifies TYK2 as a novel associated locus for idiopathic inflammatory myopathies von Jani, M, Massey, J, Wedderburn, L R, Vencovský, J, Danko, K, Lundberg, I E, Padyukov, L, Selva-O'Callaghan, A, Radstake, T, Platt, H, Warren, R B, Griffiths, C E, Lee, A, Gregersen, P K, Miller, F W, Ollier, W E, Cooper, R G, Chinoy, H, Lamb, J A

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The lived experience of juvenile idiopathic arthritis in young people receiving etanercept von Livermore, P, Eleftheriou, D, Wedderburn, L R

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Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases von Cobb, J, Cule, E, Moncrieffe, H, Hinks, A, Ursu, S, Patrick, F, Kassoumeri, L, Flynn, E, Bulatović, M, Wulffraat, N, van Zelst, B, de Jonge, R, Bohm, M, Dolezalova, P, Hirani, S, Newman, S, Whitworth, P, Southwood, T R, De Iorio, M, Wedderburn, L R, Thomson, W

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Quantitative assessment of MRI T2 relaxation time of thigh muscles in juvenile dermatomyositis von Maillard, S. M., Jones, R., Owens, C., Pilkington, C., Woo, P., Wedderburn, L. R., Murray, K. J.

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HLA class II haplotype and autoantibody associations in children with juvenile dermatomyositis and juvenile dermatomyositis–scleroderma overlap von Wedderburn, L. R., McHugh, N. J., Chinoy, H., Cooper, R. G., Salway, F., Ollier, W. E. R., McCann, L. J., Varsani, H., Dunphy, J., North, J., Davidson, J. E.

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Effective induction therapy for anti-SRP associated myositis in childhood: A small case series and review of the literature von Binns, E L, Moraitis, E, Maillard, S, Tansley, S, McHugh, N, Jacques, T S, Wedderburn, L R, Pilkington, C, Yasin, S A, Nistala, K

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Histological heterogeneity in a large clinical cohort of juvenile idiopathic inflammatory myopathy: analysis by myositis autoantibody and pathological features von Yasin, S. A., Schutz, P. W., Deakin, C. T., Sag, E., Simou, S., Marshall, L. R., Tansley, S. L., McHugh, N. J., Holton, J. L., Wedderburn, L. R., Jacques, T. S., Armon, Kate, Ellis‐Gage, Joe, Briggs, Vanja, Watts, Joanna, McCann, Liza, Roberts, Ian, Baildam, Eileen, Hanna, Lou, Lloyd, Olivia, Wadeson, Susan, Riley, Phil, McGovern, Ann, Ryder, Clive, Scott, Janis, Thomas, Beverley, Southwood, Taunton, Al‐Abadi, Eslam, Wyatt, Sue, Jackson, Gillian, Wood, Mark, VanRooyen, Vanessa, Burton, Deborah, Davidson, Joyce, Gardner‐Medwin, Janet, Martin, Neil, Waxman, Liz, Browne, Michael, Friswell, Mark, Foster, Helen, Swift, Alison, Stevenson, Vicky, Wade, Debbie, Sen, Ethan, Smith, Eve, Qiao, Lisa, Watson, Stuart, Duong, Claire, Venning, Helen, Satyapal, Rangaraj, Stretton, Elizabeth, Jordan, Mary, Mosley, Ellen, Frost, Anna, Crate, Lindsay, Warrier, Kishore, ord, Stefanie, Pilkington, Clarissa, Hasson, Nathan, Halkon, Elizabeth, Brown, Virginia, Juggins, Audrey, Smith, Sally, Lunt, Sian, Enayat, Elli, Kassoumeri, Laura, Beard, Laura, Arnold, Katie, Glackin, Yvonne, Simou, Stephanie, Almeida, Beverley, Nistala, Kiran, Dowle, Stefanie, Papadopoulou, Charis, Johnson‐Moore, Cer, Robinson, Emily, Murray, Kevin, Ioannou, John, Suffield, Linda, Al‐Obaidi, Muthana, Lee, Helen, Leach, Sam, McMahon, Anne‐Marie, Chisem, Heather, Kingshott, Ruth, Wilkinson, Nick, Inness, Emma, Kendall, Eunice, Mayers, David, Bailey, Kathryn, Fineman, Natalie, Pluess‐Hall, Helen, Akeroyd, Lou, Leahy, Alice, Collier, Amy, Cutts, Rebecca, Macleod, Emma, De Graaf, Hans, Hartfree, Sarah, Pratt, Danny

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Intravenous cyclophosphamide pulse therapy in juvenile dermatomyositis. A review of efficacy and safety von Riley, P., Maillard, S. M., Wedderburn, L. R., Woo, P., Murray, K. J., Pilkington, C. A.

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Association between duration of symptoms and severity of disease at first presentation to paediatric rheumatology: results from the Childhood Arthritis Prospective Study von Adib, N., Hyrich, K., Thornton, J., Lunt, M., Davidson, J., Gardner-Medwin, J., Foster, H., Baildam, E., Wedderburn, L., Thomson, W.

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OP0300 Do Depressive Symptoms at Disease Onset Associate with Future Disease Activity for Adolescent Patients with Jia? Results from The Childhood Arthritis Prospective Study (CAPS... von Hanns, L., Cordingley, L., Galloway, J., Norton, S., Carvalho, L.A., Christie, D., Sen, D., Carrasco, R., Rashid, A., Foster, H., Baildam, E., Cheing, A., Davidson, J., Wedderburn, L., Hyrich, K., Thomson, W., Ioannou, Y.

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