Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial von Thomas, Huw D, Calabrese, Christopher R, Batey, Michael A, Canan, Stacie, Hostomsky, Zdenek, Kyle, Suzanne, Maegley, Karen A, Newell, David R, Skalitzky, Donald, Wang, Lan-Zhen, Webber, Stephen E, Curtin, Nicola J

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Transcription inactivation through local refolding of the RNA polymerase structure von Belogurov, Georgiy A., Vassylyeva, Marina N., Sevostyanova, Anastasiya, Appleman, James R., Xiang, Alan X., Lira, Ricardo, Webber, Stephen E., Klyuyev, Sergiy, Nudler, Evgeny, Artsimovitch, Irina, Vassylyev, Dmitry G.

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Structure-based Design of Pyridone–Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition von Reich, Siegfried H, Sprengeler, Paul A, Chiang, Gary G, Appleman, James R, Chen, Joan, Clarine, Jeff, Eam, Boreth, Ernst, Justin T, Han, Qing, Goel, Vikas K, Han, Edward Z. R, Huang, Vera, Hung, Ivy N. J, Jemison, Adrianna, Jessen, Katti A, Molter, Jolene, Murphy, Douglas, Neal, Melissa, Parker, Gregory S, Shaghafi, Michael, Sperry, Samuel, Staunton, Jocelyn, Stumpf, Craig R, Thompson, Peggy A, Tran, Chinh, Webber, Stephen E, Wegerski, Christopher J, Zheng, Hong, Webster, Kevin R

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Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells von CURTIN, Nicola J, WANG, Lan-Zhen, NEWELL, David R, YIAKOUVAKI, Anthie, KYLE, Suzanne, ARRIS, Christine A, CANAN-KOCH, Stacie, WEBBER, Stephen E, DURKACZ, Barbara W, CALVERT, Hilary A, HOSTOMSKY, Zdenek

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Energy Transfer in Molecular Layer-by-Layer Films of Water-Soluble Perylene Diimides von Tang, Tingji, Herrmann, Andreas, Peneva, Kalina, Müllen, Klaus, Webber, Stephen E

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Therapeutic Benefit of a Dissociated Glucocorticoid and the Relevance of In Vitro Separation of Transrepression from Transactivation Activity von Belvisi, Maria G, Wicks, Sharon L, Battram, Clifford H, Bottoms, Stephen E. W, Redford, Jane E, Woodman, Paul, Brown, Thomas J, Webber, Stephen E, Foster, Martyn L

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Water-in-Carbon Dioxide Microemulsions with Methylated Branched Hydrocarbon Surfactants von Ryoo, Won, Webber, Stephen E, Johnston, Keith P

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Anticancer chemosensitization and radiosensitization by the novel Poly(ADP-ribose) polymerase-1 inhibitor AG14361 von CALABRESE, Christopher R, ALMASSY, Robert, LI, Jianke, MAEGLEY, Karen, NEWELL, David R, NOTARIANNI, Elena, STRATFORD, Ian J, SKALITZKY, Donald, THOMAS, Huw D, WANG, Ian-Zhen, WEBBER, Stephen E, WILLIAMS, Kaye J, BARTON, Stephanie, CURTIN, Nicola J, BATEY, Michael A, CALVERT, A. Hilary, CANAN-KOCH, Stacie, DURKACZ, Barbara W, HOSTOMSKY, Zdenek, KUMPF, Robert A, KYLE, Suzanne

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Synthesis and SAR of 3,5-diamino-piperidine derivatives: Novel antibacterial translation inhibitors as aminoglycoside mimetics von Zhou, Yuefen, Gregor, Vlad E., Ayida, Benjamin K., Winters, Geoffrey C., Sun, Zhongxiang, Murphy, Douglas, Haley, Greg, Bailey, Dwight, Froelich, Jamie M., Fish, Sarah, Webber, Stephen E., Hermann, Thomas, Wall, Daniel

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Syntheses of novel myxopyronin B analogs as potential inhibitors of bacterial RNA polymerase von Lira, Ricardo, Xiang, Alan X., Doundoulakis, Thomas, Biller, William T., Agrios, Konstantinos A., Simonsen, Klaus B., Webber, Stephen E., Sisson, Wes, Aust, Robert M., Shah, Amit M., Showalter, Richard E., Banh, Virginia N., Steffy, Kevin R., Appleman, James R.

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Water-in-carbon dioxide emulsions stabilized with hydrophobic silica particles von Adkins, Stephanie S, Gohil, Dhiren, Dickson, Jasper L, Webber, Stephen E, Johnston, Keith P

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Antibacterial activity in serum of the 3,5-diamino-piperidine translation inhibitors von Zhou, Yuefen, Chow, Chun, Murphy, Douglas E., Sun, Zhongxiang, Bertolini, Thomas, Froelich, Jamie M., Webber, Stephen E., Hermann, Thomas, Wall, Daniel

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Role of p38 MAP kinase in LPS‐induced airway inflammation in the rat von Haddad, El‐Bdaoui, Birrell, Mark, McCluskie, Kerryn, Ling, Andrea, Webber, Stephen E, Foster, Martyn L, Belvisi, Maria G

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Molecular Layer-by-Layer Self-Assembly of Water-Soluble Perylene Diimides through π−π and Electrostatic Interactions von Tang, Tingji, Qu, Jiangqiang, Müllen, Klaus, Webber, Stephen E

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A Simple and Practical Synthesis of 2-Aminoimidazoles von Little, Thomas L, Webber, Stephen E

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Photophysics of Water Soluble Perylene Diimides in Surfactant Solutions von Tang, Tingji, Peneva, Kalina, Müllen, Klaus, Webber, Stephen E

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Tricyclic Benzimidazoles as Potent Poly(ADP-ribose) Polymerase-1 Inhibitors von Skalitzky, Donald J, Marakovits, Joseph T, Maegley, Karen A, Ekker, Anne, Yu, Xiao-Hong, Hostomsky, Zdenek, Webber, Stephen E, Eastman, Brian W, Almassy, Robert, Li, Jianke, Curtin, Nicola J, Newell, David R, Calvert, A. Hilary, Griffin, Roger J, Golding, Bernard T

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Water-Soluble Perylene Diimides:  Solution Photophysics and Layer-by-Layer Incorporation into Polyelectrolyte Films von Tang, Tingji, Qu, Jianqiang, Müllen, Klaus, Webber, Stephen E

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Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase von RUEBSAM, Frank, MURPHY, Douglas E, BLAZEL, Julie K, SUN HEE KIM, YUEFEN ZHOU, QING HAN, KISSINGER, Charles R, WEBBER, Stephen E, SHOWALTER, Richard E, SHAH, Amit M, TSAN, Mei, PATEL, Rupal A, TRAN, Chinh V, THOMPSON, Peggy A, LEBRUN, Laurie A, HOU, Huiying J, KAMRAN, Ruhi, SERGEEVA, Maria V, BARTKOWSKI, Darian M, NOLAN, Thomas G, NORRIS, Daniel A, KHANDURINA, Julia, BROOKS, Jennifer, LI, Lian-Sheng, OKAMOTO, Ellen, KIRKOVSKY, Leo, JINGJING ZHAO, DRAGOVICH, Peter S, MCGUIRE, Helen M, XIANG, Alan X, ZHONGXIANG SUN, AYIDA, Benjamin K

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Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity:  Design, Synthesis, and X-ray Cocrystal Structure von Canan Koch, Stacie S, Thoresen, Lars H, Tikhe, Jayashree G, Maegley, Karen A, Almassy, Robert J, Li, Jianke, Yu, Xiao-Hong, Zook, Scott E, Kumpf, Robert A, Zhang, Cathy, Boritzki, Theodore J, Mansour, Rena N, Zhang, Kanyin E, Ekker, Anne, Calabrese, Chris R, Curtin, Nicola J, Kyle, Suzanne, Thomas, Huw D, Wang, Lan-Zhen, Calvert, A. Hilary, Golding, Bernard T, Griffin, Roger J, Newell, David R, Webber, Stephen E, Hostomsky, Zdenek

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