Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma von Sredni, Simone Treiger, Bailey, Anders W, Suri, Amreena, Hashizume, Rintaro, He, Xingyao, Louis, Nundia, Gokirmak, Tufan, Piper, David R, Watterson, Daniel M, Tomita, Tadanori

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Cloning, Expression, and Properties of the Microtubule-Stabilizing Protein STOP von Bosc, Christophe, Cronk, Jeff D., Pirollet, Fabienne, Watterson, Daniel M., Haiech, Jacques, Job, Didier, Margolis, Robert L.

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Substituted pyridazines as anti-inflammatory agents and protein kinase inhibitors von VELENTZA, ANASTASIA, HAIECH, JACQUES, LUKAS, THOMMAS J, ZASADZKI, MAGDALENA, WATTERSON, DANIEL M, VAN ELDIK, LINDA J, HIBERT, M, BOURGIGNON, JEAN-JACQUES, MIZOEVA, SALIDA, SAWKAR, ANN R

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ANTI-INFLAMMATORY AND PROTEIN KINASE INHIBITOR COMPOSITION AND METHOD OF USE von VELENTZA, ANASTASIA, SAWKAR, ANN, R, HAIECH, JACQUES, WATTERSON, DANIEL, M, ZASADZKI, MAGDALENA, VAN ELDIK, LINDA, J, BOURGUIGNON, JEAN-JACQUES, HIBERT, M, MIZOEVA, SALIDA, LUKAS, THOMAS, J

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Anti-inflammatory fused pyridazine compound von VELENTZA, ANASTASIA, SAWKAR, ANN, R, HAIECH, JACQUES, WATTERSON, DANIEL, M, ZASADZKI, MAGDALENA, VAN ELDIK, LINDA, J, BOURGUIGNON, JEAN-JACQUES, HIBERT, M, MIZOEVA, SALIDA, LUKAS, THOMAS, J

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ANTI-INFLAMMATORY AND PROTEIN KINASE INHIBITOR COMPOSITION AND METHOD OF USE von VELENTZA, ANASTASIA, SAWKAR, ANN, R, HAIECH, JACQUES, WATTERSON, DANIEL, M, ZASADZKI, MAGDALENA, VAN ELDIK, LINDA, J, BOURGUIGNON, JEAN-JACQUES, HIBERT, M, MIZOEVA, SALIDA, LUKAS, THOMAS, J

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Bruton's tyrosine kinase inhibitor BMS-986142 in experimental models of rheumatoid arthritis enhances efficacy of agents representing clinical standard-of-care von Gillooly, Kathleen M, Pulicicchio, Claudine, Pattoli, Mark A, Cheng, Lihong, Skala, Stacey, Heimrich, Elizabeth M, McIntyre, Kim W, Taylor, Tracy L, Kukral, Daniel W, Dudhgaonkar, Shailesh, Nagar, Jignesh, Banas, Dana, Watterson, Scott H, Tino, Joseph A, Fura, Aberra, Burke, James R

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A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses von Amarilla, Alberto A., Sng, Julian D. J., Parry, Rhys, Deerain, Joshua M., Potter, James R., Setoh, Yin Xiang, Rawle, Daniel J., Le, Thuy T., Modhiran, Naphak, Wang, Xiaohui, Peng, Nias Y. G., Torres, Francisco J., Pyke, Alyssa, Harrison, Jessica J., Freney, Morgan E., Liang, Benjamin, McMillan, Christopher L. D., Cheung, Stacey T. M., Guevara, Darwin J. Da Costa, Hardy, Joshua M., Bettington, Mark, Muller, David A., Coulibaly, Fasséli, Moore, Frederick, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Hobson-Peters, Jody, Suhrbier, Andreas, Watterson, Daniel, Khromykh, Alexander A.

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Evidence of a recent decline in UK emissions of hydrofluorocarbons determined by the InTEM inverse model and atmospheric measurements von Manning, Alistair J, Redington, Alison L, Say, Daniel, O'Doherty, Simon, Young, Dickon, Simmonds, Peter G, Vollmer, Martin K, Mühle, Jens, Arduini, Jgor, Spain, Gerard, Wisher, Adam, Maione, Michela, Schuck, Tanja J, Stanley, Kieran, Reimann, Stefan, Engel, Andreas, Krummel, Paul B, Fraser, Paul J, Harth, Christina M, Salameh, Peter K, Weiss, Ray F, Gluckman, Ray, Brown, Peter N, Watterson, John D, Arnold, Tim

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Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton’s Tyrosine Kinas... von Watterson, Scott H, Liu, Qingjie, Beaudoin Bertrand, Myra, Batt, Douglas G, Li, Ling, Pattoli, Mark A, Skala, Stacey, Cheng, Lihong, Obermeier, Mary T, Moore, Robin, Yang, Zheng, Vickery, Rodney, Elzinga, Paul A, Discenza, Lorell, D’Arienzo, Celia, Gillooly, Kathleen M, Taylor, Tracy L, Pulicicchio, Claudine, Zhang, Yifan, Heimrich, Elizabeth, McIntyre, Kim W, Ruan, Qian, Westhouse, Richard A, Catlett, Ian M, Zheng, Naiyu, Chaudhry, Charu, Dai, Jun, Galella, Michael A, Tebben, Andrew J, Pokross, Matt, Li, Jianqing, Zhao, Rulin, Smith, Daniel, Rampulla, Richard, Allentoff, Alban, Wallace, Michael A, Mathur, Arvind, Salter-Cid, Luisa, Macor, John E, Carter, Percy H, Fura, Aberra, Burke, James R, Tino, Joseph A

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A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses von Hardy, Joshua M., Newton, Natalee D., Modhiran, Naphak, Scott, Connor A. P., Venugopal, Hariprasad, Vet, Laura J., Young, Paul R., Hall, Roy A., Hobson-Peters, Jody, Coulibaly, Fasséli, Watterson, Daniel

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Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay von Lebani, Kebaneilwe, Jones, Martina L, Watterson, Daniel, Ranzoni, Andrea, Traves, Renee J, Young, Paul R, Mahler, Stephen M

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Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo von Clayburgh, Daniel R, Barrett, Terrence A, Tang, Yueming, Meddings, Jon B, Van Eldik, Linda J, Watterson, D Martin, Clarke, Lane L, Mrsny, Randall J, Turner, Jerrold R

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Structure and antigenicity of divergent Henipavirus fusion glycoproteins von Isaacs, Ariel, Low, Yu Shang, Macauslane, Kyle L., Seitanidou, Joy, Pegg, Cassandra L., Cheung, Stacey T. M., Liang, Benjamin, Scott, Connor A. P., Landsberg, Michael J., Schulz, Benjamin L., Chappell, Keith J., Modhiran, Naphak, Watterson, Daniel

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Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV‑2 by Disrupting the Spike–ACE2 Interaction von Guimond, Scott E., Mycroft-West, Courtney J., Gandhi, Neha S., Tree, Julia A., Le, Thuy T., Spalluto, C. Mirella, Humbert, Maria V., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Wand, Matthew, Nyström, Kristina, Said, Joanna, Setoh, Yin Xiang, Amarilla, Alberto A., Modhiran, Naphak, Sng, Julian D. J., Chhabra, Mohit, Young, Paul R., Rawle, Daniel J., Lima, Marcelo A., Yates, Edwin A., Karlsson, Richard, Miller, Rebecca L., Chen, Yen-Hsi, Bagdonaite, Ieva, Yang, Zhang, Stewart, James, Nguyen, Dung, Laidlaw, Stephen, Hammond, Edward, Dredge, Keith, Wilkinson, Tom M. A., Watterson, Daniel, Khromykh, Alexander A., Suhrbier, Andreas, Carroll, Miles W., Trybala, Edward, Bergström, Tomas, Ferro, Vito, Skidmore, Mark A., Turnbull, Jeremy E.

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An Optimized High-Throughput Immuno-Plaque Assay for SARS-CoV-2 von Amarilla, Alberto A, Modhiran, Naphak, Setoh, Yin Xiang, Peng, Nias Y G, Sng, Julian D J, Liang, Benjamin, McMillan, Christopher L D, Freney, Morgan E, Cheung, Stacey T M, Chappell, Keith J, Khromykh, Alexander A, Young, Paul R, Watterson, Daniel

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Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon von Tan, Yuen P, Xue, Yongbo, Savchenko, Andrei I, Houston, Sevan D, Modhiran, Naphak, McMillan, Christopher L. D, Boyle, Glen M, Bernhardt, Paul V, Young, Paul R, Watterson, Daniel, Williams, Craig M

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A broadly protective antibody that targets the flavivirus NS1 protein von Modhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A, Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T M, Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A P, Freney, Morgan E, Newton, Natalee D, Khromykh, Alexander A, Chappell, Keith J, Muller, David A, Stacey, Katryn J, Landsberg, Michael J, Shi, Yi, Gao, George F, Young, Paul R, Watterson, Daniel

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SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein von Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J., Khromykh, Alexander A., Chappell, Keith J., Watterson, Daniel, Woodruff, Trent M.

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Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial von Chappell, Keith J, Mordant, Francesca L, Li, Zheyi, Wijesundara, Danushka K, Ellenberg, Paula, Lackenby, Julia A, Cheung, Stacey T M, Modhiran, Naphak, Avumegah, Michael S, Henderson, Christina L, Hoger, Kym, Griffin, Paul, Bennet, Jillian, Hensen, Luca, Zhang, Wuji, Nguyen, Thi H O, Marrero-Hernandez, Sara, Selva, Kevin J, Chung, Amy W, Tran, Mai H, Tapley, Peter, Barnes, James, Reading, Patrick C, Nicholson, Suellen, Corby, Stavroula, Holgate, Thomas, Wines, Bruce D, Hogarth, P Mark, Kedzierska, Katherine, Purcell, Damian F J, Ranasinghe, Charani, Subbarao, Kanta, Watterson, Daniel, Young, Paul R, Munro, Trent P

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