Factor Xa Inhibitors:  S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides von Chan, Chuen, Borthwick, Alan D, Brown, David, Burns-Kurtis, Cynthia L, Campbell, Matthew, Chaudry, Laiq, Chung, Chun-wa, Convery, Máire A, Hamblin, J. Nicole, Johnstone, Lisa, Kelly, Henry A, Kleanthous, Savvas, Patikis, Angela, Patel, Champa, Pateman, Anthony J, Senger, Stefan, Shah, Gita P, Toomey, John R, Watson, Nigel S, Weston, Helen E, Whitworth, Caroline, Young, Robert J, Zhou, Ping

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Arylsulfonamides: A study of the relationship between activity and conformational preferences for a series of factor Xa inhibitors von Senger, Stefan, Convery, Máire A., Chan, Chuen, Watson, Nigel S.

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Sulfonamide-related conformational effects and their importance in structure-based design von Senger, Stefan, Chan, Chuen, Convery, Máire A., Hubbard, Julia A., Shah, Gita P., Watson, Nigel S., Young, Robert J.

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The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs von Watson, Nigel S., Adams, Carl, Belton, David, Brown, David, Burns-Kurtis, Cynthia L., Chaudry, Laiq, Chan, Chuen, Convery, Máire A., Davies, David E., Exall, Anne M., Harling, John D., Irvine, Stephanie, Irving, Wendy R., Kleanthous, Savvas, McLay, Iain M., Pateman, Anthony J., Patikis, Angela N., Roethke, Theresa J., Senger, Stefan, Stelman, Gary J., Toomey, John R., West, Robert I., Whittaker, Caroline, Zhou, Ping, Young, Robert J.

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Structure- and property-based design of factor Xa inhibitors: Pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs von Young, Robert J., Campbell, Matthew, Borthwick, Alan D., Brown, David, Burns-Kurtis, Cynthia L., Chan, Chuen, Convery, Máire A., Crowe, Miriam C., Dayal, Satish, Diallo, Hawa, Kelly, Henry A., Paul King, N., Kleanthous, Savvas, Mason, Andrew M., Mordaunt, Jackie E., Patel, Champa, Pateman, Anthony J., Senger, Stefan, Shah, Gita P., Smith, Paul W., Watson, Nigel S., Weston, Helen E., Zhou, Ping

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Structure and property based design of factor Xa inhibitors: Pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs von Young, Robert J., Adams, Carl, Blows, Mike, Brown, David, Burns-Kurtis, Cynthia L., Chan, Chuen, Chaudry, Laiq, Convery, Máire A., Davies, David E., Exall, Anne M., Foster, Graham, Harling, John D., Hortense, Eric, Irvine, Stephanie, Irving, Wendy R., Jackson, Steve, Kleanthous, Savvas, Pateman, Anthony J., Patikis, Angela N., Roethka, Theresa J., Senger, Stefan, Stelman, Gary J., Toomey, John R., West, Robert I., Whittaker, Caroline, Zhou, Ping, Watson, Nigel S.

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Structure and property based design of factor Xa inhibitors: Pyrrolidin-2-ones with biaryl P4 motifs von Young, Robert J., Borthwick, Alan D., Brown, David, Burns-Kurtis, Cynthia L., Campbell, Matthew, Chan, Chuen, Charbaut, Marie, Chung, Chun-wa, Convery, Máire A., Kelly, Henry A., Paul King, N., Kleanthous, Savvas, Mason, Andrew M., Pateman, Anthony J., Patikis, Angela N., Pinto, Ivan L., Pollard, Derek R., Senger, Stefan, Shah, Gita P., Toomey, John R., Watson, Nigel S., Weston, Helen E.

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Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs von Kleanthous, Savvas, Borthwick, Alan D., Brown, David, Burns-Kurtis, Cynthia L., Campbell, Matthew, Chaudry, Laiq, Chan, Chuen, Clarte, Marie-Olive, Convery, Máire A., Harling, John D., Hortense, Eric, Irving, Wendy R., Irvine, Stephanie, Pateman, Anthony J., Patikis, Angela N., Pinto, Ivan L., Pollard, Derek R., Roethka, Theresa J., Senger, Stefan, Shah, Gita P., Stelman, Gary J., Toomey, John R., Watson, Nigel S., West, Robert I., Whittaker, Caroline, Zhou, Ping, Young, Robert J.

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Structure and property based design of factor Xa inhibitors: Biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs von Young, Robert J., Borthwick, Alan D., Brown, David, Burns-Kurtis, Cynthia L., Campbell, Matthew, Chan, Chuen, Charbaut, Marie, Convery, Máire A., Diallo, Hawa, Hortense, Eric, Irving, Wendy R., Kelly, Henry A., King, N. Paul, Kleanthous, Savvas, Mason, Andrew M., Pateman, Anthony J., Patikis, Angela N., Pinto, Ivan L., Pollard, Derek R., Senger, Stefan, Shah, Gita P., Toomey, John R., Watson, Nigel S., Weston, Helen E., Zhou, Ping

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Selective and dual action orally active inhibitors of thrombin and factor Xa von Young, Robert J., Brown, David, Burns-Kurtis, Cynthia L., Chan, Chuen, Convery, Máire A., Hubbard, Julia A., Kelly, Henry A., Pateman, Anthony J., Patikis, Angela, Senger, Stefan, Shah, Gita P., Toomey, John R., Watson, Nigel S., Zhou, Ping

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Antithrombotic Potential of GW813893: A Novel, Orally Active, Active-site Directed Factor Xa Inhibitor von Abboud, Melanie A, Needle, Saul J, Burns-Kurtis, Cynthia L, Valocik, Richard E, Koster, Paul F, Amour, Augustin J, Chan, Chuen, Brown, David, Chaudry, Laiq, Zhou, Ping, Patikis, Angela, Patel, Champa, Pateman, Anthony J, Young, Rob J, Watson, Nigel S, Toomey, John R

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Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors von Watson, Nigel S., Brown, David, Campbell, Matthew, Chan, Chuen, Chaudry, Laiq, Convery, Máire A., Fenwick, Rebecca, Hamblin, J. Nicole, Haslam, Claudine, Kelly, Henry A., King, N. Paul, Kurtis, Cynthia L., Leach, Andrew R., Manchee, Gary R., Mason, Andrew M., Mitchell, Charlotte, Patel, Champa, Patel, Vipulkumar K., Senger, Stefan, Shah, Gita P., Weston, Helen E., Whitworth, Caroline, Young, Robert J.

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Thrombin inhibitors based on [5,5] trans-fused indane lactams von Pass, Martin, Abu-Rabie, Said, Baxter, Andrew, Conroy, Richard, Coote, Steven J, Craven, Andrew P, Finch, Harry, Hindley, Seán, Kelly, Henry A, Lowdon, Andrew W, McDonald, Edward, Mitchell, William L, Pegg, Neil A, Procopiou, Pan A, Ramsden, Nigel G, Thomas, Rhian, Walker, Dawn A, Watson, Nigel S, Jhoti, Harren, Mooney, Christopher J, Tang, Chi-Man, Thomas, Pamela J, Parry, Simon, Patel, Champa

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THE SQUALESTATINS, NOVEL INHIBITORS OF SQUALENE SYNTHASE PRODUCED BY A SPECIES OF PHOMA: II. STRUCTURE ELUCIDATION von SIDEBOTTOM, PHILIP J., HIGHCOCK, RONA M., LANE, STEPHEN J., PROCOPIOU, PAN A., WATSON, NIGEL S.

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The squalestatins: Synthesis of c-4 carboxamide derivatives von Chan, Chuen, Scicinski, Jan J, Srikantha, Anton Rp, Watson, Nigel S

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The Squalestatins:  Decarboxy and 4-Deoxy Analogues as Potent Squalene Synthase Inhibitors von Chan, Chuen, Andreotti, Daniele, Cox, Brian, Dymock, Brian W, Hutson, Julie L, Keeling, Suzanne E, McCarthy, Alun D, Procopiou, Panayiotis A, Ross, Barry C, Sareen, Meenu, Scicinski, Jan J, Sharratt, Peter J, Snowden, Michael A, Watson, Nigel S

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Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors von Procopiou, Panayiotis A, Draper, Christopher D, Hutson, Julie L, Inglis, Graham G. A, Ross, Barry C, Watson, Nigel S

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The Squalestatins:  Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in Vivo Evaluation of C3-Modified Analogues von Procopiou, Panayiotis A, Cox, Brian, Kirk, Barrie E, Lester, Michael G, McCarthy, Alun D, Sareen, Meenu, Sharratt, Peter J, Snowden, Michael A, Spooner, Stephen J, Watson, Nigel S, Widdowson, Julia

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SUPPORT BASE FOR SECURING A LINEAR MOTION GUIDE TRACK von Watson, Nigel S

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SYSTEM, METHOD, AND APPARATUS FOR HOLDING A TRACK TO A BASE von WATSON, Nigel, S

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