Triazole oxytocin antagonists: Identification of an aryloxyazetidine replacement for a biaryl substituent von Brown, Alan, Brown, T. Bruce, Calabrese, Andrew, Ellis, Dave, Puhalo, Nicholas, Ralph, Michael, Watson, Lesa

Volltext

Triazole oxytocin antagonists: Identification of aryl ether replacements for a biaryl substituent von Brown, Alan, Brown, Lindsay, Brown, T. Bruce, Calabrese, Andrew, Ellis, Dave, Puhalo, Nicholas, Smith, Chris R., Wallace, Olga, Watson, Lesa

Volltext

Design and optimization of potent, selective antagonists of Oxytocin von Brown, Alan, Brown, Lindsay, Ellis, Dave, Puhalo, Nicholas, Smith, Chris R., Wallace, Olga, Watson, Lesa

Volltext

Process Development toward a Pro-Drug of Buprenorphine von Berrell, Sophie L, Byard, Stephen J, Carey, John S, Codina, Antonio, Davis, J. Alf, Filer, Katherine, Garnett, Alasdair, Marshall, Robin, Martin, Stephen J, Mykytiuk, John, Northen, Julian, Pandya, Urvish, Reid, Gary, Smyth, Catherine, Watson, Lesa

Volltext

The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile-Part 1 von Tran, Thien Duc, Wakenhut, Florian, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Brimage, Rebecca A., Halstead, Rebecca, Glen, Rebecca, Wilson, Craig P., Adam, Fiona, Hay, Duncan, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C.

Volltext

The discovery of UK-369003, a novel PDE5 inhibitor with the potential for oral bioavailability and dose-proportional pharmacokinetics von Rawson, David J., Ballard, Stephen, Barber, Christopher, Barker, Laura, Beaumont, Kevin, Bunnage, Mark, Cole, Susan, Corless, Martin, Denton, Stephen, Ellis, David, Floc’h, Marion, Foster, Laura, Gosset, James, Holmwood, Frances, Lane, Charlotte, Leahy, David, Mathias, John, Maw, Graham, Million, William, Poinsard, Cedric, Price, Jenny, Russel, Rachel, Street, Stephen, Watson, Lesa

Volltext

Non-benzimidazole containing inhibitors of respiratory syncytial virus von Pryde, David C., Tran, Thien-Duc, Gardner, Iain, Bright, Helen, Stupple, Paul, Galan, Sebastien, Alsop, Liam, Watson, Lesa, Middleton, Donald S., Dayal, Satish, Platts, Michelle, Murray, Edward J., Parkinson, Tanya, Webster, Robert

Volltext

The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile-Part 2 von Wakenhut, Florian, Tran, Thien Duc, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Stonehouse, David, Cheung, Kathy, Wybrow, Robert, Daverio, Felice, Crook, Samuel, Statham, Keith, Leese, David, Stead, Darren, Adam, Fiona, Hay, Duncan, Roberts, Lee R., Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Goetz, Gilles H., Che, Ye, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C.

Volltext

Design and synthesis of pyridazinone-based 5-HT2C agonists von ALLERTON, Charlotte M. N, ANDREWS, Mark D, WARD, Robin, WATSON, Lesa, BLAGG, Julian, ELLIS, David, EVRARD, Edel, GREEN, Martin P, LIU, Kevin K.-C, MCMURRAY, Gordon, RALPH, Michael, SANDERSON, Vivienne

Volltext

The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile--Part1 von Tran, Thien Duc, Wakenhut, Florian, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Brimage, Rebecca A, Halstead, Rebecca, Glen, Rebecca, Wilson, Craig P, Adam, Fiona, Hay, Duncan, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C

Volltext

The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile--Part2 von Wakenhut, Florian, Tran, Thien Duc, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Stonehouse, David, Cheung, Kathy, Wybrow, Robert, Daverio, Felice, Crook, Samuel, Statham, Keith, Leese, David, Stead, Darren, Adam, Fiona, Hay, Duncan, Roberts, Lee R, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C, Goetz, Gilles H, Che, Ye, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C

Volltext

Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT2c agonists von ANDREWS, Mark D, GREEN, Martin P, WATSON, Lesa, ALLERTON, Charlotte M. N, BATCHELOR, David V, BLAGG, Julian, BROWN, Alan D, GORDON, David W, MCMURRAY, Gordon, MILLNS, Daniel J, NICHOLS, Carly L

Volltext

Design and synthesis of pyridazinone-based 5-HT sub(2C) agonists von Allerton, Charlotte MN, Andrews, Mark D, Blagg, Julian, Ellis, David, Evrard, Edel, Green, Martin P, Liu, Kevin K-C, McMurray, Gordon, Ralph, Michael, Sanderson, Vivienne, Ward, Robin, Watson, Lesa

Volltext

Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT sub(2C) agonists von Andrews, Mark D, Green, Martin P, Allerton, Charlotte MN, Batchelor, David V, Blagg, Julian, Brown, Alan D, Gordon, David W, McMurray, Gordon, Millns, Daniel J, Nichols, Carly L, Watson, Lesa

Volltext

Design and synthesis of pyridazinone-based 5-HT 2C agonists von Allerton, Charlotte M.N., Andrews, Mark D., Blagg, Julian, Ellis, David, Evrard, Edel, Green, Martin P., Liu, Kevin K.-C., McMurray, Gordon, Ralph, Michael, Sanderson, Vivienne, Ward, Robin, Watson, Lesa

Volltext

Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT 2C agonists von Andrews, Mark D., Green, Martin P., Allerton, Charlotte M.N., Batchelor, David V., Blagg, Julian, Brown, Alan D., Gordon, David W., McMurray, Gordon, Millns, Daniel J., Nichols, Carly L., Watson, Lesa

Volltext

Design and synthesis of pyridazinone-based 5-HT(2C) agonists von Allerton, Charlotte M N, Andrews, Mark D, Blagg, Julian, Ellis, David, Evrard, Edel, Green, Martin P, Liu, Kevin K-C, McMurray, Gordon, Ralph, Michael, Sanderson, Vivienne, Ward, Robin, Watson, Lesa

Volltext

Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT(2C) agonists von Andrews, Mark D, Green, Martin P, Allerton, Charlotte M N, Batchelor, David V, Blagg, Julian, Brown, Alan D, Gordon, David W, McMurray, Gordon, Millns, Daniel J, Nichols, Carly L, Watson, Lesa

Volltext

Spirocyclic Derivatives von RAWSON DAVID JAMES, SWAIN NIGEL ALAN, WATSON LESA

Volltext bestellen

SPIROCYCLIC QUINAZOLINE DERIVATIVES AND THEIR USE AS PDE7 INHIBITORS von WATSON, LESA, RAWSON, DAVID, JAMES, SWAIN, NIGEL, ALAN

Volltext bestellen