ROBUST HYPERPARAMETER ESTIMATION PROTECTS AGAINST HYPERVARIABLE GENES AND IMPROVES POWER TO DETECT DIFFERENTIAL EXPRESSION von Phipso, Belinda, Lee, Stanley, Majewski, Ian J., Alexander, Warren S., Smyth, Gordon K.

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The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism von Murphy, James M., Czabotar, Peter E., Hildebrand, Joanne M., Lucet, Isabelle S., Zhang, Jian-Guo, Alvarez-Diaz, Silvia, Lewis, Rowena, Lalaoui, Najoua, Metcalf, Donald, Webb, Andrew I., Young, Samuel N., Varghese, Leila N., Tannahill, Gillian M., Hatchell, Esme C., Majewski, Ian J., Okamoto, Toru, Dobson, Renwick C.J., Hilton, Douglas J., Babon, Jeffrey J., Nicola, Nicos A., Strasser, Andreas, Silke, John, Alexander, Warren S.

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The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis von Alvarez-Diaz, Silvia, Dillon, Christopher P., Lalaoui, Najoua, Tanzer, Maria C., Rodriguez, Diego A., Lin, Ann, Lebois, Marion, Hakem, Razq, Josefsson, Emma C., O’Reilly, Lorraine A., Silke, John, Alexander, Warren S., Green, Douglas R., Strasser, Andreas

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NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells von Masters, Seth L., Gerlic, Motti, Metcalf, Donald, Preston, Simon, Pellegrini, Marc, O’Donnell, Joanne A., McArthur, Kate, Baldwin, Tracey M., Chevrier, Stephane, Nowell, Cameron J., Cengia, Louise H., Henley, Katya J., Collinge, Janelle E., Kastner, Daniel L., Feigenbaum, Lionel, Hilton, Douglas J., Alexander, Warren S., Kile, Benjamin T., Croker, Ben A.

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NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS von Louis, Cynthia, Souza-Fonseca-Guimaraes, Fernando, Yang, Yuyan, D'Silva, Damian, Kratina, Tobias, Dagley, Laura, Hediyeh-Zadeh, Soroor, Rautela, Jai, Masters, Seth Lucian, Davis, Melissa J, Babon, Jeffrey J, Ciric, Bogoljub, Vivier, Eric, Alexander, Warren S, Huntington, Nicholas D, Wicks, Ian P

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Solid-state polymer electrolytes for high-performance lithium metal batteries von Choudhury, Snehashis, Stalin, Sanjuna, Vu, Duylinh, Warren, Alexander, Deng, Yue, Biswal, Prayag, Archer, Lynden A.

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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL von Lawlor, Kate E., Khan, Nufail, Mildenhall, Alison, Gerlic, Motti, Croker, Ben A., D’Cruz, Akshay A., Hall, Cathrine, Kaur Spall, Sukhdeep, Anderton, Holly, Masters, Seth L., Rashidi, Maryam, Wicks, Ian P., Alexander, Warren S., Mitsuuchi, Yasuhiro, Benetatos, Christopher A., Condon, Stephen M., Wong, W. Wei-Lynn, Silke, John, Vaux, David L., Vince, James E.

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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death von Hildebrand, Joanne M., Tanzer, Maria C., Lucet, Isabelle S., Young, Samuel N., Spall, Sukhdeep K., Sharma, Pooja, Pierotti, Catia, Garnier, Jean-Marc, Dobson, Renwick C.J., Webb, Andrew I., Tripaydonis, Anne, Babon, Jeffrey J., Mulcair, Mark D., Scanlon, Martin J., Alexander, Warren S., Wilks, Andrew F., Czabotar, Peter E., Lessene, Guillaume, Murphy, James M., Silke, John

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RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis von Rickard, James A., O’Donnell, Joanne A., Evans, Joseph M., Lalaoui, Najoua, Poh, Ashleigh R., Rogers, TeWhiti, Vince, James E., Lawlor, Kate E., Ninnis, Robert L., Anderton, Holly, Hall, Cathrine, Spall, Sukhdeep K., Phesse, Toby J., Abud, Helen E., Cengia, Louise H., Corbin, Jason, Mifsud, Sandra, Di Rago, Ladina, Metcalf, Donald, Ernst, Matthias, Dewson, Grant, Roberts, Andrew W., Alexander, Warren S., Murphy, James M., Ekert, Paul G., Masters, Seth L., Vaux, David L., Croker, Ben A., Gerlic, Motti, Silke, John

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CIS is a potent checkpoint in NK cell–mediated tumor immunity von Delconte, Rebecca B, Kolesnik, Tatiana B, Dagley, Laura F, Rautela, Jai, Shi, Wei, Putz, Eva M, Stannard, Kimberley, Zhang, Jian-Guo, Teh, Charis, Firth, Matt, Ushiki, Takashi, Andoniou, Christopher E, Degli-Esposti, Mariapia A, Sharp, Phillip P, Sanvitale, Caroline E, Infusini, Giuseppe, Liau, Nicholas P D, Linossi, Edmond M, Burns, Christopher J, Carotta, Sebastian, Gray, Daniel H D, Seillet, Cyril, Hutchinson, Dana S, Belz, Gabrielle T, Webb, Andrew I, Alexander, Warren S, Li, Shawn S, Bullock, Alex N, Babon, Jeffery J, Smyth, Mark J, Nicholson, Sandra E, Huntington, Nicholas D

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Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans von Choi, Jarny, Baldwin, Tracey M, Wong, Mae, Bolden, Jessica E, Fairfax, Kirsten A, Lucas, Erin C, Cole, Rebecca, Biben, Christine, Morgan, Clare, Ramsay, Kerry A, Ng, Ashley P, Kauppi, Maria, Corcoran, Lynn M, Shi, Wei, Wilson, Nick, Wilson, Michael J, Alexander, Warren S, Hilton, Douglas J, de Graaf, Carolyn A

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Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia von Glaser, Stefan P, Lee, Erinna F, Trounson, Evelyn, Bouillet, Philippe, Wei, Andrew, Fairlie, W Douglas, Izon, David J, Zuber, Johannes, Rappaport, Amy R, Herold, Marco J, Alexander, Warren S, Lowe, Scott W, Robb, Lorraine, Strasser, Andreas

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Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells von Ushiki, Takashi, Huntington, Nicholas D, Glaser, Stefan P, Kiu, Hiu, Georgiou, Angela, Zhang, Jian-Guo, Metcalf, Donald, Nicola, Nicos A, Roberts, Andrew W, Alexander, Warren S

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The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal von Yang, Yuqing, Kueh, Andrew J., Grant, Zoe L., Abeysekera, Waruni, Garnham, Alexandra L., Wilcox, Stephen, Hyland, Craig D., Di Rago, Ladina, Metcalf, Don, Alexander, Warren S., Coultas, Leigh, Smyth, Gordon K., Voss, Anne K., Thomas, Tim

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Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop von Tanzer, Maria C, Tripaydonis, Anne, Webb, Andrew I, Young, Samuel N, Varghese, Leila N, Hall, Cathrine, Alexander, Warren S, Hildebrand, Joanne M, Silke, John, Murphy, James M

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cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner von Wong, W. Wei-Lynn, Vince, James E., Lalaoui, Najoua, Lawlor, Kate E., Chau, Diep, Bankovacki, Aleksandra, Anderton, Holly, Metcalf, Donald, O'Reilly, Lorraine, Jost, Philipp J., Murphy, James M., Alexander, Warren S., Strasser, Andreas, Vaux, David L., Silke, John

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Haematopoietic stem cells: past, present and future von Ng, Ashley P, Alexander, Warren S

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A study of the application of graphite MALDI to the analysis of lanthanides and deconvolution of the isobaric species observed von Conway, Ulric, Warren, Alexander D, Gates, Paul J

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Electrodeposition of Zinc in Aqueous Electrolytes Containing High Molecular Weight Polymers von Zhang, Duhan, Warren, Alexander J, Li, Gaojin, Cheng, Zhu, Han, Xiaoxing, Zhao, Qing, Liu, Xiaotun, Deng, Yue, Archer, Lynden A

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The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15 von Delconte, Rebecca B., Shi, Wei, Sathe, Priyanka, Ushiki, Takashi, Seillet, Cyril, Minnich, Martina, Kolesnik, Tatiana B., Rankin, Lucille C., Mielke, Lisa A., Zhang, Jian-Guo, Busslinger, Meinrad, Smyth, Mark J., Hutchinson, Dana S., Nutt, Stephen L., Nicholson, Sandra E., Alexander, Warren S., Corcoran, Lynn M., Vivier, Eric, Belz, Gabrielle T., Carotta, Sebastian, Huntington, Nicholas D.

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