Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization von Graves, Bradford, Thompson, Thelma, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Di Lello, Paola, Fry, David, Garvie, Colin, Huang, Kuo-Sen, Gao, Lin, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T

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Rational Design of Highly Selective Spleen Tyrosine Kinase Inhibitors von Lucas, Matthew C., Goldstein, David M., Hermann, Johannes C., Kuglstatter, Andreas, Liu, Wenjian, Luk, Kin Chun, Padilla, Fernando, Slade, Michelle, Villaseñor, Armando G., Wanner, Jutta, Xie, Wenwei, Zhang, Xiaohu, Liao, Cheng

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The mechanism of action of ramoplanin and enduracidin von Fang, Xiao, Tiyanont, Kittichoat, Zhang, Yi, Wanner, Jutta, Boger, Dale, Walker, Suzanne

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Reversible linkage of two distinct small molecule inhibitors of Myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines von Wanner, Jutta, Romashko, Darlene, Werner, Douglas S, May, Earl W, Peng, Yue, Schulz, Ryan, Foreman, Kenneth W, Russo, Suzanne, Arnold, Lee D, Pingle, Maneesh, Bergstrom, Donald E, Barany, Francis, Thomson, Stuart

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Recent advances in malaria drug discovery von Biamonte, Marco A., Wanner, Jutta, Le Roch, Karine G.

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Total Synthesis of the Ramoplanin A2 and Ramoplanose Aglycon von Jiang, Wanlong, Wanner, Jutta, Lee, Richard J, Bounaud, Pierre-Yves, Boger, Dale L

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Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc von Lemoine, Rémy C., Petersen, Ann C., Setti, Lina, Baldinger, Thomas, Wanner, Jutta, Jekle, Andreas, Heilek, Gabrielle, deRosier, André, Ji, Changhua, Rotstein, David M.

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Abstract 226: Optimization of folate receptor alpha-targeting tunable drug conjugates von Sigler, Sara C., Gupta, Vinayak, Nguyen, Hanh N., Rood, Michael K., Wanner, Jutta, Werner, Doug S.

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Abstract 5153: Tunable Drug Conjugates: a differentiated drug conjugate (DC) platform von Hickey, Sara C., Nanna, Alex R., Nguyen, Hanh N., Ofori, Leslie, Rader, Christoph, Rood, Michael K., Wanner, Jutta, Werner, Doug S.

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Pyrrolopyrazines as Selective Spleen Tyrosine Kinase Inhibitors von Padilla, Fernando, Bhagirath, Niala, Chen, Shaoqing, Chiao, Eric, Goldstein, David M, Hermann, Johannes C, Hsu, Jonathan, Kennedy-Smith, Joshua J, Kuglstatter, Andreas, Liao, Cheng, Liu, Wenjian, Lowrie, Lee E, Luk, Kin Chun, Lynch, Stephen M, Menke, John, Niu, Linghao, Owens, Timothy D, O-Yang, Counde, Railkar, Aruna, Schoenfeld, Ryan C, Slade, Michelle, Steiner, Sandra, Tan, Yun-Chou, Villaseñor, Armando G, Wang, Ce, Wanner, Jutta, Xie, Wenwei, Xu, Daigen, Zhang, Xiaohu, Zhou, Mingyan, Lucas, Matthew C

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Abstract B43: Reversible linkage of two distinct small molecule inhibitors of MYC generates a more potent and selective dimeric inhibitor that is active in cancer cell lines over-e... von Wanner, Jutta, Romashko, Darlene, Werner, Douglas S., May, Earl W., Peng, Yue, Schulz, Ryan, Foreman, Kenneth W., Russo, Suzanne, Arnold, Lee D., Pingle, Maneesh, Bergstrom, Donald E., Barany, Francis, Thomson, Stuart

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Evaluation of secondary amide replacements in a series of CCR5 antagonists as a means to increase intrinsic membrane permeability. Part 1: Optimization of gem-disubstituted azacycl... von Lemoine, Rémy C., Petersen, Ann C., Setti, Lina, Wanner, Jutta, Jekle, Andreas, Heilek, Gabrielle, deRosier, André, Ji, Changhua, Berry, Pamela, Rotstein, David

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Activation of the p53 pathway by small-moleculeinduced MDM2 and MDMX dimerization von Graves, Bradford, Thompson, Thelma, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Di Lello, Paola, Fry, David, Garvie, Colin, Huang, Kuo-Sen, Gao, Lin, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T.

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Abstract C128: Small-molecule antagonists of MDM2 and MDMX von Thompson, Thelma, Graves, Bradford, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Huang, Kuo-Sen, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T.

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Lewis Acid-Directed Cyclocondensation of Piperidone Enol Ethers with 2-Methoxy-4-(N-phenylsulfonyl)-1,4-benzoquinoneimine:  A New Regioselective Synthesis of Oxygenated Carbolines... von Engler, Thomas A, Wanner, Jutta

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Total Synthesis of the Ramoplanin A2 and Ramoplanose Aglycon von Jiang, Wanlong, Wanner, Jutta, Lee, Richard J., Bounaud, Pierre-Yves, Boger, Dale L.

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Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists von Lemoine, Rémy C., Petersen, Ann C., Setti, Lina, Chen, Lijing, Wanner, Jutta, Jekle, Andreas, Heilek, Gabrielle, deRosier, André, Ji, Changhua, Rotstein, David M.

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Evaluation of amide replacements in CCR5 antagonists as a means to increase intrinsic permeability. Part 2: SAR optimization and pharmacokinetic profile of a homologous azacyle ser... von Wanner, Jutta, Chen, Lijing, Lemoine, Rémy C., Kondru, Rama, Jekle, Andreas, Heilek, Gabrielle, deRosier, André, Ji, Changhua, Berry, Pamela W., Rotstein, David M.

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Novel hexahydropyrrolo[3,4- c]pyrrole CCR5 antagonists von Rotstein, David M., Melville, Chris R., Padilla, Fernando, Cournoyer, Dick, Lee, Eun K., Lemoine, Remy, Petersen, Ann C., Setti, Lina Q., Wanner, Jutta, Chen, Lijing, Filonova, Lubov, Loughhead, David G., Manka, Jason, Lin, Xiao-Fa, Gleason, Shelley, Sankuratri, Surya, Ji, Changhua, deRosier, Andre, Dioszegi, Marianna, Heilek, Gabrielle, Jekle, Andreas, Berry, Pamela, Mau, Cheng-I, Weller, Paul

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A dual metathesis route to oligomeric sulfonamides von Wanner, Jutta, Harned, Andrew M, Probst, Donald A, Poon, Kevin W.C, Klein, Thomas A, Snelgrove, Kelley A, Hanson, Paul R

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