A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia von Zeng, Andy G. X., Bansal, Suraj, Jin, Liqing, Mitchell, Amanda, Chen, Weihsu Claire, Abbas, Hussein A., Chan-Seng-Yue, Michelle, Voisin, Veronique, van Galen, Peter, Tierens, Anne, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Daver, Naval, Futreal, P. Andrew, Minden, Mark D., Kennedy, James A., Wang, Jean C. Y., Dick, John E.

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The Capable ABL: What Is Its Biological Function? von Wang, Jean Y. J.

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Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia von Škrtić, Marko, Sriskanthadevan, Shrivani, Jhas, Bozhena, Gebbia, Marinella, Wang, Xiaoming, Wang, Zezhou, Hurren, Rose, Jitkova, Yulia, Gronda, Marcela, Maclean, Neil, Lai, Courteney K., Eberhard, Yanina, Bartoszko, Justyna, Spagnuolo, Paul, Rutledge, Angela C., Datti, Alessandro, Ketela, Troy, Moffat, Jason, Robinson, Brian H., Cameron, Jessie H., Wrana, Jeffery, Eaves, Connie J., Minden, Mark D., Wang, Jean C.Y., Dick, John E., Humphries, Keith, Nislow, Corey, Giaever, Guri, Schimmer, Aaron D.

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DNA damage-induced cell death relies on SLFN11-dependent cleavage of distinct type II tRNAs von Li, Manqing, Kao, Elaine, Malone, Dane, Gao, Xia, Wang, Jean Y. J., David, Michael

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A 17-gene stemness score for rapid determination of risk in acute leukaemia von Ng, Stanley W. K., Mitchell, Amanda, Kennedy, James A., Chen, Weihsu C., McLeod, Jessica, Ibrahimova, Narmin, Arruda, Andrea, Popescu, Andreea, Gupta, Vikas, Schimmer, Aaron D., Schuh, Andre C., Yee, Karen W., Bullinger, Lars, Herold, Tobias, Görlich, Dennis, Büchner, Thomas, Hiddemann, Wolfgang, Berdel, Wolfgang E., Wörmann, Bernhard, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Metzeler, Klaus, Buske, Christian, Löwenberg, Bob, Valk, Peter J. M., Zandstra, Peter W., Minden, Mark D., Dick, John E., Wang, Jean C. Y.

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Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells von Notta, Faiyaz, Mullighan, Charles G., Wang, Jean C. Y., Poeppl, Armando, Doulatov, Sergei, Phillips, Letha A., Ma, Jing, Minden, Mark D., Downing, James R., Dick, John E.

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Tracing the origins of relapse in acute myeloid leukaemia to stem cells von Shlush, Liran I., Mitchell, Amanda, Heisler, Lawrence, Abelson, Sagi, Ng, Stanley W. K., Trotman-Grant, Aaron, Medeiros, Jessie J. F., Rao-Bhatia, Abilasha, Jaciw-Zurakowsky, Ivana, Marke, Rene, McLeod, Jessica L., Doedens, Monica, Bader, Gary, Voisin, Veronique, Xu, ChangJiang, McPherson, John D., Hudson, Thomas J., Wang, Jean C. Y., Minden, Mark D., Dick, John E.

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CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells von Surka, Christine, Jin, Liqing, Mbong, Nathan, Lu, Chin-Chun, Jang, In Sock, Rychak, Emily, Mendy, Derek, Clayton, Thomas, Tindall, Elizabeth, Hsu, Christy, Fontanillo, Celia, Tran, Eileen, Contreras, Adrian, Ng, Stanley W.K., Matyskiela, Mary, Wang, Kai, Chamberlain, Philip, Cathers, Brian, Carmichael, James, Hansen, Joshua, Wang, Jean C.Y., Minden, Mark D., Fan, Jinhong, Pierce, Daniel W., Pourdehnad, Michael, Rolfe, Mark, Lopez-Girona, Antonia, Dick, John E., Lu, Gang

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Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia von Shlush, Liran I., Zandi, Sasan, Mitchell, Amanda, Chen, Weihsu Claire, Brandwein, Joseph M., Gupta, Vikas, Kennedy, James A., Schimmer, Aaron D., Schuh, Andre C., Yee, Karen W., McLeod, Jessica L., Doedens, Monica, Medeiros, Jessie J. F., Marke, Rene, Kim, Hyeoung Joon, Lee, Kwon, McPherson, John D., Hudson, Thomas J., Pan-Leukemia Gene Panel Consortium, The HALT, Brown, Andrew M. K., Yousif, Fouad, Trinh, Quang M., Stein, Lincoln D., Minden, Mark D., Wang, Jean C. Y., Dick, John E.

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Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia von Schenk, Tino, Chen, Weihsu Claire, Göllner, Stefanie, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Popescu, Andreea C, Burnett, Alan, Mills, Ken, Casero, Robert A, Marton, Laurence, Woster, Patrick, Minden, Mark D, Dugas, Martin, Wang, Jean C Y, Dick, John E, Müller-Tidow, Carsten, Petrie, Kevin, Zelent, Arthur

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Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia von Cole, Alicia, Wang, Zezhou, Coyaud, Etienne, Voisin, Veronique, Gronda, Marcela, Jitkova, Yulia, Mattson, Rachel, Hurren, Rose, Babovic, Sonja, Maclean, Neil, Restall, Ian, Wang, Xiaoming, Jeyaraju, Danny V., Sukhai, Mahadeo A., Prabha, Swayam, Bashir, Shaheena, Ramakrishnan, Ashwin, Leung, Elisa, Qia, Yi Hua, Zhang, Nianxian, Combes, Kevin R., Ketela, Troy, Lin, Fengshu, Houry, Walid A., Aman, Ahmed, Al-awar, Rima, Zheng, Wei, Wienholds, Erno, Xu, Chang Jiang, Dick, John, Wang, Jean C.Y., Moffat, Jason, Minden, Mark D., Eaves, Connie J., Bader, Gary D., Hao, Zhenyue, Kornblau, Steven M., Raught, Brian, Schimmer, Aaron D.

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miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells von Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.

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Targeting the RB-pathway in Cancer Therapy von KNUDSEN, Erik S, WANG, Jean Y. J

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Colonoscopy polyp detection and classification: Dataset creation and comparative evaluations von Li, Kaidong, Fathan, Mohammad I, Patel, Krushi, Zhang, Tianxiao, Zhong, Cuncong, Bansal, Ajay, Rastogi, Amit, Wang, Jean S, Wang, Guanghui

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TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding von Petrova, Penka S, Viller, Natasja Nielsen, Wong, Mark, Pang, Xinli, Lin, Gloria H Y, Dodge, Karen, Chai, Vien, Chen, Hui, Lee, Vivian, House, Violetta, Vigo, Noel T, Jin, Debbie, Mutukura, Tapfuma, Charbonneau, Marilyse, Truong, Tran, Viau, Stephane, Johnson, Lisa D, Linderoth, Emma, Sievers, Eric L, Maleki Vareki, Saman, Figueredo, Rene, Pampillo, Macarena, Koropatnick, James, Trudel, Suzanne, Mbong, Nathan, Jin, Liqing, Wang, Jean C Y, Uger, Robert A

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Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells von Nieborowska-Skorska, Margaret, Sullivan, Katherine, Dasgupta, Yashodhara, Podszywalow-Bartnicka, Paulina, Hoser, Grazyna, Maifrede, Silvia, Martinez, Esteban, Di Marcantonio, Daniela, Bolton-Gillespie, Elisabeth, Cramer-Morales, Kimberly, Lee, Jaewong, Li, Min, Slupianek, Artur, Gritsyuk, Daniel, Cerny-Reiterer, Sabine, Seferynska, Ilona, Stoklosa, Tomasz, Bullinger, Lars, Zhao, Huaqing, Gorbunova, Vera, Piwocka, Katarzyna, Valent, Peter, Civin, Curt I, Muschen, Markus, Dick, John E, Wang, Jean Cy, Bhatia, Smita, Bhatia, Ravi, Eppert, Kolja, Minden, Mark D, Sykes, Stephen M, Skorski, Tomasz

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FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination von Guo, Elaine, Ishii, Yuki, Mueller, James, Srivatsan, Anjana, Gahman, Timothy, Putnam, Christopher D., Wang, Jean Y. J., Kolodner, Richard D.

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A gene regulatory network for root epidermis cell differentiation in Arabidopsis von Bruex, Angela, Kainkaryam, Raghunandan M, Wieckowski, Yana, Kang, Yeon Hee, Bernhardt, Christine, Xia, Yang, Zheng, Xiaohua, Wang, Jean Y, Lee, Myeong Min, Benfey, Philip, Woolf, Peter J, Schiefelbein, John

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Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study von Castelo-Branco, Pedro, PhD, Choufani, Sanaa, PhD, Mack, Stephen, BSc, Gallagher, Denis, PhD, Zhang, Cindy, MSc, Lipman, Tatiana, MSc, Zhukova, Nataliya, MD, Walker, Erin J, PhD, Martin, Dianna, PhD, Merino, Diana, MSc, Wasserman, Jonathan D, MD, Elizabeth, Cynthia, MSc, Alon, Noa, BSc, Zhang, Libo, PhD, Hovestadt, Volker, MSc, Kool, Marcel, PhD, Jones, David TW, PhD, Zadeh, Gelareh, MD, Croul, Sidney, Prof, Hawkins, Cynthia, MD, Hitzler, Johann, MD, Wang, Jean CY, MD, Baruchel, Sylvain, Prof, Dirks, Peter B, Prof, Malkin, David, Prof, Pfister, Stefan, MD, Taylor, Michael D, MD, Weksberg, Rosanna, Prof, Tabori, Uri, Dr

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Cell Death Response to DNA Damage von Wang, Jean Y J

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