Targeting DYRK1A/B kinases to modulate p21‐cyclin D1‐p27 signalling and induce anti‐tumour activity in a model of human glioblastoma von Massey, Andrew J., Benwell, Karen, Burbridge, Mike, Kotschy, Andras, Walmsley, David Lee

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Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B von Lee Walmsley, David, Murray, James B, Dokurno, Pawel, Massey, Andrew J, Benwell, Karen, Fiumana, Andrea, Foloppe, Nicolas, Ray, Stuart, Smith, Julia, Surgenor, Allan E, Edmonds, Thomas, Demarles, Didier, Burbridge, Mike, Cruzalegui, Francisco, Kotschy, Andras, Hubbard, Roderick E

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Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors von Weber, Csaba, Sipos, Melinda, Paczal, Attila, Balint, Balazs, Kun, Vilibald, Foloppe, Nicolas, Dokurno, Pawel, Massey, Andrew J, Walmsley, David Lee, Hubbard, Roderick E, Murray, James, Benwell, Karen, Edmonds, Thomas, Demarles, Didier, Bruno, Alain, Burbridge, Mike, Cruzalegui, Francisco, Kotschy, Andras

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Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity von Yamada, Yousuke, Takashima, Hajime, Walmsley, David Lee, Ushiyama, Fumihito, Matsuda, Yohei, Kanazawa, Harumi, Yamaguchi-Sasaki, Toru, Tanaka-Yamamoto, Nozomi, Yamagishi, Junya, Kurimoto-Tsuruta, Risa, Ogata, Yuya, Ohtake, Norikazu, Angove, Hayley, Baker, Lisa, Harris, Richard, Macias, Alba, Robertson, Alan, Surgenor, Allan, Watanabe, Hayato, Nakano, Koichiro, Mima, Masashi, Iwamoto, Kunihiko, Okada, Atsushi, Takata, Iichiro, Hitaka, Kosuke, Tanaka, Akihiro, Fujita, Kiyoko, Sugiyama, Hiroyuki, Hubbard, Roderick E

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ALPHA-AMINO AMIDE DERIVATIVES von TAKASHIMA, Hajime, KIM, Chunhae, USHIYAMA, Fumihito, YAMADA, Yousuke, WALMSLEY, David Lee, MATSUDA, Yohei, ROUGHLEY, Stephen David, ARRATE, Alba Teresa Macias, YAMAGISHI, Junya, YOSHIZUMI, Takashi, McKENNA, Sean

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Novel alpha-amino amide derivatives von Yohei Matsuda, Stephen David Roughley, Hajime Takashima, Takashi Yoshizumi, Yousuke Yamada, Chunhae Kim, David Lee Walmsley, Junya Yamagishi, Sean McKenna, Fumihito Ushiyama, Alba Teresa Macias Arrate

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PYRIMIDINE DERIVATIVES AS AURORA A AND AURORA B INHIBITORS von DRYSDALE, MARTIN, JAMES, WALMSLEY, LEE, DAVID, GRAHAM, CHRISTOPHER

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PYRAZINE DERIVATIVES AND THEIR USE IN THERAPY von DRYSDALE, MARTIN JAMES, WALMSLEY, LEE DAVID, CHEN, IJEN

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PYRAZOLE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER AND AUTOIMMUNE DISORDERS von DRYSDALE MARTIN JAMES, FROMONT CHRISTOPHE, NORTHFIELD CHRISTOPHER JOHN, WALMSLEY DAVID LEE

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PYRAZOLE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER AND AUTOIMMUNE DISORDERS von FROMONT, CHRISTOPHE, DRYSDALE, MARTIN, JAMES, NORTHFIELD, CHRISTOPHER J, WALMSLEY, DAVID, LEE

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PYRAZOLE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER AND AUTOIMMUNE DISORDERS von NORTHFIELD, CHRISTOPHER, JOHN, FROMONT, CHRISTOPHE, DRYSDALE, MARTIN, JAMES, WALMSLEY, DAVID, LEE

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Identification and Specification of the Mouse Skeletal Stem Cell von Chan, Charles K.F., Seo, Eun Young, Chen, James Y., Lo, David, McArdle, Adrian, Sinha, Rahul, Tevlin, Ruth, Seita, Jun, Vincent-Tompkins, Justin, Wearda, Taylor, Lu, Wan-Jin, Senarath-Yapa, Kshemendra, Chung, Michael T., Marecic, Owen, Tran, Misha, Yan, Kelley S., Upton, Rosalynd, Walmsley, Graham G., Lee, Andrew S., Sahoo, Debashis, Kuo, Calvin J., Weissman, Irving L., Longaker, Michael T.

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Protocol for the development of a core outcome set for clinical trials in primary sclerosing cholangitis von Hussain, Nasir, Ma, Christopher, Hirschfield, Gideon, Walmsley, Martine, Hanford, Paula, Vesterhus, Mette, Kowdley, Kris, Bergquist, Annika, Ponsioen, Cyriel, Levy, Cynthia, Assis, David, Schramm, Christoph, Bowlus, Christopher, Trauner, Michael, Aiyegbusi, Olalekan Lee, Jairath, Vipul, Trivedi, Palak J

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Increased CD4 : CD8 ratio normalization with implementation of current ART management guidelines von Zhabokritsky, Alice, Szadkowski, Leah, Cooper, Curtis, Loutfy, Mona, Wong, Alexander, McClean, Alison, Hogg, Robert S, Walmsley, Sharon L

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Invasive Pneumococcal Disease Among Immunocompromised Persons: Implications for Vaccination Programs von Shigayeva, Altynay, Rudnick, Wallis, Green, Karen, Chen, Danny K., Demczuk, Walter, Gold, Wayne L., Johnstone, Jennie, Kitai, Ian, Krajden, Sigmund, Lovinsky, Reena, Muller, Matthew, Powis, Jeff, Rau, Neil, Walmsley, Sharon, Tyrrell, Gregory, Bitnun, Ari, McGeer, Allison

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Time-Resolved X‑ray Photoelectron Spectroscopy: Ultrafast Dynamics in CS2 Probed at the S 2p Edge von Gabalski, Ian, Allum, Felix, Seidu, Issaka, Britton, Mathew, Brenner, Günter, Bromberger, Hubertus, Brouard, Mark, Bucksbaum, Philip H., Burt, Michael, Cryan, James P., Driver, Taran, Ekanayake, Nagitha, Erk, Benjamin, Garg, Diksha, Gougoula, Eva, Heathcote, David, Hockett, Paul, Holland, David M. P., Howard, Andrew J., Kumar, Sonu, Lee, Jason W. L., Li, Siqi, McManus, Joseph, Mikosch, Jochen, Milesevic, Dennis, Minns, Russell S., Neville, Simon, Atia-Tul-Noor, Papadopoulou, Christina C., Passow, Christopher, Razmus, Weronika O., Röder, Anja, Rouzée, Arnaud, Simao, Alcides, Unwin, James, Vallance, Claire, Walmsley, Tiffany, Wang, Jun, Rolles, Daniel, Stolow, Albert, Schuurman, Michael S., Forbes, Ruaridh

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A Method for Displaying Incremental Validity with Expectancy Charts von Lee, Samuel David, Walmsley, Philip T, Sackett, Paul R., Kuncel, Nathan

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457. EVALUATING THE ACCURACY OF CLINICAL SIEWERT CLASSIFICATION, A RETROSPECTIVE REVIEW OF 807 PATIENTS von Walmsley, James, Ariyarathenam, Arun, Berrisford, Richard, Humphreys, Lee, Sanders, Grant, Tham, Ji Chung, Wheatley, Tim, Chan, David SY

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464. OUTCOMES AFTER CURATIVE RESECTION FOR GASTRO-ESOPHAGEAL JUNCTION ADENOCARCINOMA von Walmsley, James, Ariyarathenam, Arun, Berrisford, Richard, Humphreys, Lee, Sanders, Grant, Tham, Ji Chung, Wheatley, Tim, Chan, David SY

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467. DISTRIBUTION OF LYMPH NODE INVOLVEMENT IN PATIENTS WITH GASTRO-ESOPHAGEAL JUNCTION ADENOCARCINOMA von Walmsley, James, Ariyarathenam, Arun, Berrisford, Richard, Humphreys, Lee, Sanders, Grant, Tham, Ji Chung, Wheatley, Tim, Chan, David SY

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