Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway von Das, Utpal, Wang, Lina, Ganguly, Archan, Saikia, Junmi M, Wagner, Steven L, Koo, Edward H, Roy, Subhojit

Volltext

Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease von Kwak, Sang Su, Washicosky, Kevin J., Brand, Emma, von Maydell, Djuna, Aronson, Jenna, Kim, Susan, Capen, Diane E., Cetinbas, Murat, Sadreyev, Ruslan, Ning, Shen, Bylykbashi, Enjana, Xia, Weiming, Wagner, Steven L., Choi, Se Hoon, Tanzi, Rudolph E., Kim, Doo Yeon

Volltext

A three-dimensional human neural cell culture model of Alzheimer’s disease von Choi, Se Hoon, Kim, Young Hye, Hebisch, Matthias, Sliwinski, Christopher, Lee, Seungkyu, D’Avanzo, Carla, Chen, Hechao, Hooli, Basavaraj, Asselin, Caroline, Muffat, Julien, Klee, Justin B., Zhang, Can, Wainger, Brian J., Peitz, Michael, Kovacs, Dora M., Woolf, Clifford J., Wagner, Steven L., Tanzi, Rudolph E., Kim, Doo Yeon

Volltext

Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons von van der Kant, Rik, Langness, Vanessa F., Herrera, Cheryl M., Williams, Daniel A., Fong, Lauren K., Leestemaker, Yves, Steenvoorden, Evelyne, Rynearson, Kevin D., Brouwers, Jos F., Helms, J. Bernd, Ovaa, Huib, Giera, Martin, Wagner, Steven L., Bang, Anne G., Goldstein, Lawrence S.B.

Volltext

Advances in the pathophysiology of pre-eclampsia and related podocyte injury von Craici, Iasmina M., Wagner, Steven J., Weissgerber, Tracey L., Grande, Joseph P., Garovic, Vesna D.

Volltext

Facultative endosymbionts mediate dietary breadth in a polyphagous herbivore von Wagner, Steven M., Martinez, Adam J., Ruan, Yong-Ming, Kim, Kyungsun L., Lenhart, Paul A., Dehnel, Allison C., Oliver, Kerry M., White, Jennifer A.

Volltext

Preclinical validation of a potent gamma-secretase modulator for Alzheimer's disease prevention von Rynearson, Kevin D., Ponnusamy, Moorthi, Prikhodko, Olga, Xie, Yuhuan, Zhang, Can, Nguyen, Phuong, Hug, Brenda, Sawa, Mariko, Becker, Ann, Spencer, Brian, Florio, Jazmin, Mante, Michael, Salehi, Bahar, Arias, Carlos, Galasko, Douglas, Head, Brian P., Johnson, Graham, Lin, Jiunn H., Duddy, Steven K., Rissman, Robert A., Mobley, William C., Thinakaran, Gopal, Tanzi, Rudolph E., Wagner, Steven L.

Volltext

TDLAS-based NH3 mole fraction measurement for exhaust diagnostics during selective catalytic reduction using a fiber-coupled 2.2-µm DFB diode laser von Stritzke, Felix, Diemel, Oliver, Wagner, Steven

Volltext

Experimental investigation of the flue gas thermochemical composition of an oxy-fuel swirl burner von Bürkle, Sebastian, Becker, Lukas Georg, Dreizler, Andreas, Wagner, Steven

Volltext

STIM1, an essential and conserved component of store-operated Ca²⁺ channel function von Roos, Jack, DiGregorio, Paul J, Yeromin, Andriy V, Ohlsen, Kari, Lioudyno, Maria, Zhang, Shenyuan, Safrina, Olga, Kozak, J. Ashot, Wagner, Steven L, Cahalan, Michael D, Veliçelebi, Gönůl, Stauderman, Kenneth A

Volltext

Broadband supercontinuum laser absorption spectrometer for multiparameter gas phase combustion diagnostics von Göran Blume, Niels, Wagner, Steven

Volltext

Posterior Reversible Encephalopathy Syndrome and Eclampsia: Pressing the Case for More Aggressive Blood Pressure Control von Wagner, Steven J., MD, Acquah, Letitia A., MD, Lindell, E. Paul, MD, Craici, Iasmina M., MD, Wingo, Majken T., MD, Rose, Carl H., MD, White, Wendy M., MD, August, Phyllis, MD, Garovic, Vesna D., MD

Volltext

Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury von White, Wendy M, Garrett, Angelica T, Craici, Iasmina M, Wagner, Steven J, Fitz-Gibbon, Patrick D, Butters, Kim A, Brost, Brian C, Rose, Carl H, Grande, Joseph P, Garovic, Vesna D

Volltext

Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE von Bertram, Lars, Lange, Christoph, Mullin, Kristina, Parkinson, Michele, Hsiao, Monica, Hogan, Meghan F., Schjeide, Brit M.M., Hooli, Basavaraj, DiVito, Jason, Ionita, Iuliana, Jiang, Hongyu, Laird, Nan, Moscarillo, Thomas, Ohlsen, Kari L., Elliott, Kathryn, Wang, Xin, Hu-Lince, Diane, Ryder, Marie, Murphy, Amy, Wagner, Steven L., Blacker, Deborah, Becker, K. David, Tanzi, Rudolph E.

Volltext

A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP von Weissmiller, April M, Natera-Naranjo, Orlangie, Reyna, Sol M, Pearn, Matthew L, Zhao, Xiaobei, Nguyen, Phuong, Cheng, Soan, Goldstein, Lawrence S B, Tanzi, Rudolph E, Wagner, Steven L, Mobley, William C, Wu, Chengbiao

Volltext

Urinalysis is more specific and urinary neutrophil gelatinase-associated lipocalin is more sensitive for early detection of acute kidney injury von Schinstock, Carrie A, Semret, Merfake H, Wagner, Steven J, Borland, Timothy M, Bryant, Sandra C, Kashani, Kianoush B, Larson, Timothy S, Lieske, John C

Volltext

Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease von Kounnas, Maria Z., Danks, Anne M., Cheng, Soan, Tyree, Curtis, Ackerman, Elizabeth, Zhang, Xulun, Ahn, Kwangwook, Nguyen, Phuong, Comer, Dan, Mao, Long, Yu, Chengzhi, Pleynet, David, Digregorio, Paul J., Velicelebi, Gonul, Stauderman, Kenneth A., Comer, William T., Mobley, William C., Li, Yue-Ming, Sisodia, Sangram S., Tanzi, Rudolph E., Wagner, Steven L.

Volltext

Effect of Potent γ-Secretase Modulator in Human Neurons Derived From Multiple Presenilin 1–Induced Pluripotent Stem Cell Mutant Carriers von Liu, Qing, Waltz, Shannon, Woodruff, Grace, Ouyang, Joe, Israel, Mason A, Herrera, Cheryl, Sarsoza, Floyd, Tanzi, Rudolph E, Koo, Edward H, Ringman, John M, Goldstein, Lawrence S. B, Wagner, Steven L, Yuan, Shauna H

Volltext

Reduction of the expression of the late-onset Alzheimer’s disease (AD) risk-factor BIN1 does not affect amyloid pathology in an AD mouse model von Andrew, Robert J., De Rossi, Pierre, Nguyen, Phuong, Kowalski, Haley R., Recupero, Aleksandra J., Guerbette, Thomas, Krause, Sofia V., Rice, Richard C., Laury-Kleintop, Lisa, Wagner, Steven L., Thinakaran, Gopal

Volltext

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase von Jankowsky, Joanna L., Fadale, Daniel J., Anderson, Jeffrey, Xu, Guilian M., Gonzales, Victoria, Jenkins, Nancy A., Copeland, Neal G., Lee, Michael K., Younkin, Linda H., Wagner, Steven L., Younkin, Steven G., Borchelt, David R.

Volltext