The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1 von Delacroix, Sinny, Wagner, Jill M, Kobayashi, Masahiko, Yamamoto, Ken-ichi, Karnitz, Larry M

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Cisplatin-Induced DNA Damage Activates Replication Checkpoint Signaling Components that Differentially Affect Tumor Cell Survival von Wagner, Jill M, Karnitz, Larry M

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53BP1 as a potential predictor of response in PARP inhibitor-treated homologous recombination-deficient ovarian cancer von Hurley, Rachel M., Wahner Hendrickson, Andrea E., Visscher, Daniel W., Ansell, Peter, Harrell, Maria I., Wagner, Jill M., Negron, Vivian, Goergen, Krista M., Maurer, Matthew J., Oberg, Ann L., Meng, X. Wei, Flatten, Karen S., De Jonge, Maja J.A., Van Herpen, Carla D., Gietema, Jourik A., Koornstra, Rutger H.T., Jager, Agnes, den Hollander, Martha W., Dudley, Matthew, Shepherd, Stacie P., Swisher, Elizabeth M., Kaufmann, Scott H.

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Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil von Geng, Liyi, Huehls, Amelia M, Wagner, Jill M, Huntoon, Catherine J, Karnitz, Larry M

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Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination von Huehls, Amelia M., Huntoon, Catherine J., Joshi, Poorval M., Baehr, Carly A., Wagner, Jill M., Wang, Xiaoxiao, Lee, Marietta Y., Karnitz, Larry M.

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Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combination von Huehls, Amelia M, Wagner, Jill M, Huntoon, Catherine J, Karnitz, Larry M

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Pharmacological Abrogation of S-Phase Checkpoint Enhances the Anti-Tumor Activity of Gemcitabine In Vivo von Matthews, David J., Yakes, Michael, Chen, Jason, Tadano, Michele, Bornheim, Lester, Clary, Douglas O., Tai, Albert, Wagner, Jill M., Miller, Nicole, Kim, Yong D., Robertson, Scott, Murray, Louis, Karnitz, Larry M.

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Prospects for the Use of ATR Inhibitors to Treat Cancer von Wagner, Jill M, Kaufmann, Scott H

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Characterization of a RAD51C -silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance von Hurley, Rachel M, McGehee, Cordelia D, Nesic, Ksenija, Correia, Cristina, Weiskittel, Taylor M, Kelly, Rebecca L, Venkatachalam, Annapoorna, Hou, Xiaonan, Pathoulas, Nicholas M, Meng, X Wei, Kondrashova, Olga, Radke, Marc R, Schneider, Paula A, Flatten, Karen S, Peterson, Kevin L, Becker, Marc A, Wong, Ee Ming, Southey, Melissa S, Dobrovic, Alexander, Lin, Kevin K, Harding, Thomas C, McNeish, Iain, Ross, Christian A, Wagner, Jill M, Wakefield, Matthew J, Scott, Clare L, Haluska, Paul, Wahner Hendrickson, Andrea E, Karnitz, Larry M, Swisher, Elizabeth M, Li, Hu, Weroha, S John, Kaufmann, Scott H

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Poly(ADP-Ribose) Polymerase Inhibition Synergizes with 5-Fluorodeoxyuridine but not 5-Fluorouracil in Ovarian Cancer Cells von HUEHLS, Amelia M, WAGNER, Jill M, HUNTOON, Catherine J, LIYI GENG, ERLICHMAN, Charles, PATEL, Anand G, KAUFMANN, Scott H, KARNITZ, Larry M

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Chaperoning Checkpoint Kinase 1 (Chk1), an Hsp90 Client, with Purified Chaperones von Arlander, Sonnet J.H., Felts, Sara J., Wagner, Jill M., Stensgard, Bridget, Toft, David O., Karnitz, Larry M.

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CHFR and Paclitaxel Sensitivity of Ovarian Cancer von Wahner Hendrickson, Andrea E, Visscher, Daniel W, Hou, Xiaonan, Goergen, Krista M, Atkinson, Hunter J, Beito, Thomas G, Negron, Vivian, Lingle, Wilma L, Bruzek, Amy K, Hurley, Rachel M, Wagner, Jill M, Flatten, Karen S, Peterson, Kevin L, Schneider, Paula A, Larson, Melissa C, Maurer, Matthew J, Kalli, Kimberly R, Oberg, Ann L, Weroha, S John, Kaufmann, Scott H

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Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival von Karnitz, Larry M, Flatten, Karen S, Wagner, Jill M, Loegering, David, Hackbarth, Jennifer S, Arlander, Sonnet J H, Vroman, Benjamin T, Thomas, M Bijoy, Baek, Yong-Un, Hopkins, Kevin M, Lieberman, Howard B, Chen, Junjie, Cliby, William A, Kaufmann, Scott H

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Substituted 3-Imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino- [6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as Highly Selective and Potent Inhibitors of Glycogen Syntha... von Engler, Thomas A, Henry, James R, Malhotra, Sushant, Cunningham, Brian, Furness, Kelly, Brozinick, Joseph, Burkholder, Timothy P, Clay, Michael P, Clayton, Joshua, Diefenbacher, Clive, Hawkins, Eric, Iversen, Philip W, Li, Yihong, Lindstrom, Terry D, Marquart, Angela L, McLean, Johnathan, Mendel, David, Misener, Elizabeth, Briere, Daniel, O'Toole, John C, Porter, Warren J, Queener, Steven, Reel, Jon K, Owens, Rebecca A, Brier, Richard A, Eessalu, Thomas E, Wagner, Jill R, Campbell, Robert M, Vaughn, Renee

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Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-β type I receptor kinase domain von SAWYER, J. Scott, BEIGHT, Douglas W, PARSONS, Stephen, SMITH, Edward C. R, WAGNER, Jill R, LEI YAN, FAMING ZHANG, YINGLING, Jonathan M, BRITT, Karen S, ANDERSON, Bryan D, CAMPBELL, Robert M, GOODSON, Theodore JR, HERRON, David K, LI, Hong-Yu, MCMILLEN, William T, MORT, Nicholas

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Gender Diverse Youth: Opportunities to Identify and Address Systemic Inequities von Forcier, Michelle, Wagner, Jill, Holland, Sabina

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The development of potent and selective bisarylmaleimide GSK3 inhibitors von Engler, Thomas A., Malhotra, Sushant, Burkholder, Timothy P., Henry, James R., Mendel, David, Porter, Warren J., Furness, Kelly, Diefenbacher, Clive, Marquart, Angela, Reel, Jon K., Li, Yihong, Clayton, Joshua, Cunningham, Brian, McLean, Johnathan, O’Toole, John C., Brozinick, Joseph, Hawkins, Eric, Misener, Elizabeth, Briere, Daniel, Brier, Richard A., Wagner, Jill R., Campbell, Robert M., Anderson, Bryan D., Vaughn, Renee, Bennett, Donald B., Meier, Timothy I., Cook, James A.

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Overcoming S-Phase Checkpoint-Mediated Resistance: Sequence-Dependent Synergy of Gemcitabine and 7-Ethyl-10-hydroxycamptothecin (SN-38) in Human Carcinoma Cell Lines von Gálvez-Peralta, Marina, Dai, Nga T, Loegering, David A, Flatten, Karen S, Safgren, Stephanie L, Wagner, Jill M, Ames, Matthew M, Karnitz, Larry M, Kaufmann, Scott H

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Dihydropyrrolopyrazole Transforming Growth Factor-β Type I Receptor Kinase Domain Inhibitors:  A Novel Benzimidazole Series with Selectivity versus Transforming Growth Factor-β Typ... von Li, Hong-yu, Wang, Yan, Heap, Charles R, King, Chi-Hsin R, Mundla, Sreenivasa R, Voss, Matthew, Clawson, David K, Yan, Lei, Campbell, Robert M, Anderson, Bryan D, Wagner, Jill R, Britt, Karen, Lu, Ku X, McMillen, William T, Yingling, Jonathan M

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Localization of eosinophil-derived neurotoxin and eosinophil cationic protein in neutrophilic leukocytes von Sur, Sanjiv, Glitz, Dohn G., Kita, Hirohito, Kujawa, Stephen M., Peterson, Ellen A., Weiler, Deborah A., Kephart, Gail M., Wagner, Jill M., George, Terry J., Gleich, Gerald J., Leiferman, Kristin M.

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