How Machine Learning Will Transform Biomedicine von Goecks, Jeremy, Jalili, Vahid, Heiser, Laura M., Gray, Joe W.

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Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target von Timmerman, Luika A., Holton, Thomas, Yuneva, Mariia, Louie, Raymond J., Padró, Mercè, Daemen, Anneleen, Hu, Min, Chan, Denise A., Ethier, Stephen P., van ‘t Veer, Laura J., Polyak, Kornelia, McCormick, Frank, Gray, Joe W.

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Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics von Goodspeed, Andrew, Heiser, Laura M, Gray, Joe W, Costello, James C

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Metrics other than potency reveal systematic variation in responses to cancer drugs von Fallahi-Sichani, Mohammad, Honarnejad, Saman, Heiser, Laura M, Gray, Joe W, Sorger, Peter K

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Development of a nanoparticle-based immunotherapy targeting PD-L1 and PLK1 for lung cancer treatment von Reda, Moataz, Ngamcherdtrakul, Worapol, Nelson, Molly A., Siriwon, Natnaree, Wang, Ruijie, Zaidan, Husam Y., Bejan, Daniel S., Reda, Sherif, Hoang, Ngoc Ha, Crumrine, Noah A., Rehwaldt, Justin P. C., Bindal, Akash, Mills, Gordon B., Gray, Joe W., Yantasee, Wassana

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Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis von Tsujikawa, Takahiro, Kumar, Sushil, Borkar, Rohan N., Azimi, Vahid, Thibault, Guillaume, Chang, Young Hwan, Balter, Ariel, Kawashima, Rie, Choe, Gina, Sauer, David, El Rassi, Edward, Clayburgh, Daniel R., Kulesz-Martin, Molly F., Lutz, Eric R., Zheng, Lei, Jaffee, Elizabeth M., Leyshock, Patrick, Margolin, Adam A., Mori, Motomi, Gray, Joe W., Flint, Paul W., Coussens, Lisa M.

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Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway von Nan, Xiaolin, Tanja M. Tamgüney, Eric A. Collisson, Li-Jung Lin, Cameron Pitt, Jacqueline Galeas, Sophia Lewis, Joe W. Gray, Frank McCormick, Steven Chu

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Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges von Lovci, Michael T, Ghanem, Dana, Marr, Henry, Arnold, Justin, Gee, Sherry, Parra, Marilyn, Liang, Tiffany Y, Stark, Thomas J, Gehman, Lauren T, Hoon, Shawn, Massirer, Katlin B, Pratt, Gabriel A, Black, Douglas L, Gray, Joe W, Conboy, John G, Yeo, Gene W

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Cationic Polymer Modified Mesoporous Silica Nanoparticles for Targeted siRNA Delivery to HER2+ Breast Cancer von Ngamcherdtrakul, Worapol, Morry, Jingga, Gu, Shenda, Castro, David J., Goodyear, Shaun M., Sangvanich, Thanapon, Reda, Moataz M., Lee, Richard, Mihelic, Samuel A., Beckman, Brandon L., Hu, Zhi, Gray, Joe W., Yantasee, Wassana

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Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer von Risom, Tyler, Langer, Ellen M., Chapman, Margaret P., Rantala, Juha, Fields, Andrew J., Boniface, Christopher, Alvarez, Mariano J., Kendsersky, Nicholas D., Pelz, Carl R., Johnson-Camacho, Katherine, Dobrolecki, Lacey E., Chin, Koei, Aswani, Anil J., Wang, Nicholas J., Califano, Andrea, Lewis, Michael T., Tomlin, Claire J., Spellman, Paul T., Adey, Andrew, Gray, Joe W., Sears, Rosalie C.

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Exome Sequencing of Cell-Free DNA from Metastatic Cancer Patients Identifies Clinically Actionable Mutations Distinct from Primary Disease von Butler, Timothy M, Johnson-Camacho, Katherine, Peto, Myron, Wang, Nicholas J, Macey, Tara A, Korkola, James E, Koppie, Theresa M, Corless, Christopher L, Gray, Joe W, Spellman, Paul T

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Detecting cancer by monitoring circulating tumor DNA von Spellman, Paul T, Gray, Joe W

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HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment von Weigelt, Britta, Lo, Alvin T, Park, Catherine C, Gray, Joe W, Bissell, Mina J

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Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling von Nan, Xiaolin, Collisson, Eric A., Lewis, Sophia, Huang, Jing, Tamgüney, Tanja M., Liphardt, Jan T., McCormick, Frank, Gray, Joe W., Chu, Steven

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Pathologic Complete Response Predicts Recurrence-Free Survival More Effectively by Cancer Subset: Results From the I-SPY 1 TRIAL—CALGB 150007/150012, ACRIN 6657 von ESSERMAN, Laura J, BERRY, Donald A, LIVASY, Chad, KRONTIRAS, Helen, MONTGOMERY, Leslie, TRIPATHY, Debasish, LEHMAN, Constance, LIU, Minetta C, OLOPADE, Olufunmilayo I, RUGO, Hope S, CARPENTER, John T, DRESSLER, Lynn, DEMICHELE, Angela, CHHIENG, David, SINGH, Baljit, MIES, Carolyn, RABBAN, Joseph, CHEN, Yunn-Yi, GIRI, Dilip, VAN'T VEER, Laura, HYLTON, Nola, CAREY, Lisa, DAVIS, Sarah E, BUXTON, Meredith, HUDIS, Cliff, GRAY, Joe W, PEROU, Charles, YAU, Christina

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CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion von Jiao, Xuanmao, Velasco-Velázquez, Marco A, Wang, Min, Li, Zhiping, Rui, Hallgeir, Peck, Amy R, Korkola, James E, Chen, Xuelian, Xu, Shaohua, DuHadaway, James B, Guerrero-Rodriguez, Sandra, Addya, Sankar, Sicoli, Daniela, Mu, Zhaomei, Zhang, Gang, Stucky, Andres, Zhang, Xi, Cristofanilli, Massimo, Fatatis, Alessandro, Gray, Joe W, Zhong, Jiang F, Prendergast, George C, Pestell, Richard G

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Restriction of Receptor Movement Alters Cellular Response: Physical Force Sensing by EphA2 von Salaita, Khalid, Nair, Pradeep M, Petit, Rebecca S, Neve, Richard M, Das, Debopriya, Gray, Joe W, Groves, Jay T

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CUL4A Induces Epithelial-Mesenchymal Transition and Promotes Cancer Metastasis by Regulating ZEB1 Expression von YUNSHAN WAN, MINGXIN WEN, LABARGE, Mark A, LIANG YOU, KOGAN, Scott C, GRAY, Joe W, MAO, Jian-Hua, GUANGWEI WEI, YONGWON KWON, YANGYANG XU, YUEYONG LIU, PENGJU ZHANG, XIUQUAN HE, QIN WANG, YURONG HUANG, JEN, Kuang-Yu

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Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast von Campbell, Michael J., Baehner, Frederick, O’Meara, Tess, Ojukwu, Ekene, Han, Booyeon, Mukhtar, Rita, Tandon, Vickram, Endicott, Max, Zhu, Zelos, Wong, Jasmine, Krings, Gregor, Au, Alfred, Gray, Joe W., Esserman, Laura

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Bayesian Network Inference Modeling Identifies TRIB1 as a Novel Regulator of Cell-Cycle Progression and Survival in Cancer Cells von Gendelman, Rina, Xing, Heming, Mirzoeva, Olga K, Sarde, Preeti, Curtis, Christina, Feiler, Heidi S, McDonagh, Paul, Gray, Joe W, Khalil, Iya, Korn, W Michael

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