Generation of L Cells in Mouse and Human Small Intestine Organoids von PETERSEN, Natalia, REIMANN, Frank, BARTFELD, Sina, FARIN, Henner F, RINGNALDA, Femke C, VRIES, Robert G. J, VAN DEN BRINK, Stieneke, CLEVERS, Hans, GRIBBLE, Fiona M, DE KONING, Eelco J. P

Volltext

A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology von Xu, Xiaoxi, Kumari, Rajendra, Zhou, Jun, Chen, Jing, Mao, Binchen, Wang, Jingjing, Zheng, Meiling, Tu, Xiaolong, An, Xiaoyu, Chen, Xiaobo, Zhang, Likun, Tian, Xiaoli, Wang, Haojie, Dong, Xin, Bao, Zhengzheng, Guo, Sheng, Ouyang, Xuesong, Shang, Limei, Wang, Fei, Yan, Xuefei, Zhang, Rui, Vries, Robert G J, Clevers, Hans, Li, Qi-Xiang

Volltext

The Organoid Cell Atlas von Bock, Christoph, Boutros, Michael, Camp, J. Gray, Clarke, Laura, Clevers, Hans, Knoblich, Juergen A., Liberali, Prisca, Regev, Aviv, Rios, Anne C., Stegle, Oliver, Stunnenberg, Hendrik G., Teichmann, Sarah A., Treutlein, Barbara, Vries, Robert G. J.

Volltext

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids von Bolhaqueiro, Ana C. F., Ponsioen, Bas, Bakker, Bjorn, Klaasen, Sjoerd J., Kucukkose, Emre, van Jaarsveld, Richard H., Vivié, Judith, Verlaan-Klink, Ingrid, Hami, Nizar, Spierings, Diana C. J., Sasaki, Nobuo, Dutta, Devanjali, Boj, Sylvia F., Vries, Robert G. J., Lansdorp, Peter M., van de Wetering, Marc, van Oudenaarden, Alexander, Clevers, Hans, Kranenburg, Onno, Foijer, Floris, Snippert, Hugo J. G., Kops, Geert J. P. L.

Volltext

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis von Huch, Meritxell, Bonfanti, Paola, Boj, Sylvia F, Sato, Toshiro, Loomans, Cindy J M, van de Wetering, Marc, Sojoodi, Mozhdeh, Li, Vivian S W, Schuijers, Jurian, Gracanin, Ana, Ringnalda, Femke, Begthel, Harry, Hamer, Karien, Mulder, Joyce, van Es, Johan H, de Koning, Eelco, Vries, Robert G J, Heimberg, Harry, Clevers, Hans

Volltext

The SWI/SNF Chromatin-remodeling Complex Is a Cofactor for Tat Transactivation of the HIV Promoter von Mahmoudi, Tokameh, Parra, Maribel, Vries, Robert G.J., Kauder, Steven E., Verrijzer, C. Peter, Ott, Melanie, Verdin, Eric

Volltext

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ von Farin, Henner F, Karthaus, Wouter R, Kujala, Pekka, Rakhshandehroo, Maryam, Schwank, Gerald, Vries, Robert G J, Kalkhoven, Eric, Nieuwenhuis, Edward E S, Clevers, Hans

Volltext

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis von Mahmoudi, Tokameh, Boj, Sylvia F, Hatzis, Pantelis, Li, Vivian S W, Taouatas, Nadia, Vries, Robert G J, Teunissen, Hans, Begthel, Harry, Korving, Jeroen, Mohammed, Shabaz, Heck, Albert J R, Clevers, Hans

Volltext

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance von Li, Ningning, Babaei-Jadidi, Roya, Lorenzi, Federica, Spencer-Dene, Bradley, Clarke, Philip, Domingo, Enric, Tulchinsky, Eugene, Vries, Robert G. J., Kerr, David, Pan, Yihang, He, Yulong, Bates, David O., Tomlinson, Ian, Clevers, Hans, Nateri, Abdolrahman S.

Volltext

The kinase TNIK is an essential activator of Wnt target genes von Mahmoudi, Tokameh, Li, Vivian S W, Ng, Ser Sue, Taouatas, Nadia, Vries, Robert G J, Mohammed, Shabaz, Heck, Albert J, Clevers, Hans

Volltext

Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures von Karthaus, Wouter R., Iaquinta, Phillip J., Drost, Jarno, Gracanin, Ana, van Boxtel, Ruben, Wongvipat, John, Dowling, Catherine M., Gao, Dong, Begthel, Harry, Sachs, Norman, Vries, Robert G.J., Cuppen, Edwin, Chen, Yu, Sawyers, Charles L., Clevers, Hans C.

Volltext

Stem cells and cancer of the stomach and intestine von Vries, Robert G.J., Huch, Meritxell, Clevers, Hans

Volltext

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium von Sato, Toshiro, Stange, Daniel E, Ferrante, Marc, Vries, Robert G.J, van Es, Johan H, van den Brink, Stieneke, van Houdt, Winan J, Pronk, Apollo, van Gorp, Joost, Siersema, Peter D, Clevers, Hans

Volltext

G970R‐CFTR Mutation (c.2908G>C) Results Predominantly in a Splicing Defect von Fidler, Meredith C., Buckley, Alexandra, Sullivan, James C., Statia, Marvin, Boj, Sylvia F., Vries, Robert G. J., Munck, Anne, Higgins, Mark, Moretto Zita, Matteo, Negulescu, Paul, Goor, Fredrick, De Boeck, Kris

Volltext

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients von van de Wetering, Marc, Francies, Hayley E., Francis, Joshua M., Bounova, Gergana, Iorio, Francesco, Pronk, Apollo, van Houdt, Winan, van Gorp, Joost, Taylor-Weiner, Amaro, Kester, Lennart, McLaren-Douglas, Anne, Blokker, Joyce, Jaksani, Sridevi, Bartfeld, Sina, Volckman, Richard, van Sluis, Peter, Li, Vivian S.W., Seepo, Sara, Sekhar Pedamallu, Chandra, Cibulskis, Kristian, Carter, Scott L., McKenna, Aaron, Lawrence, Michael S., Lichtenstein, Lee, Stewart, Chip, Koster, Jan, Versteeg, Rogier, van Oudenaarden, Alexander, Saez-Rodriguez, Julio, Vries, Robert G.J., Getz, Gad, Wessels, Lodewyk, Stratton, Michael R., McDermott, Ultan, Meyerson, Matthew, Garnett, Mathew J., Clevers, Hans

Volltext

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis von Berkers, Gitte, van Mourik, Peter, Vonk, Annelotte M., Kruisselbrink, Evelien, Dekkers, Johanna F., de Winter-de Groot, Karin M., Arets, Hubertus G.M., Marck-van der Wilt, Rozemarijn E.P., Dijkema, Jasper S., Vanderschuren, Maaike M., Houwen, Roderick H.J., Heijerman, Harry G.M., van de Graaf, Eduard A., Elias, Sjoerd G., Majoor, Christof J., Koppelman, Gerard H., Roukema, Jolt, Bakker, Marleen, Janssens, Hettie M., van der Meer, Renske, Vries, Robert G.J., Clevers, Hans C., de Jonge, Hugo R., Beekman, Jeffrey M., van der Ent, Cornelis K.

Volltext

Organoid Models of Human and Mouse Ductal Pancreatic Cancer von Boj, Sylvia F., Hwang, Chang-Il, Baker, Lindsey A., Chio, Iok In Christine, Engle, Dannielle D., Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S., Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H., van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D., Wilson, John P., Feigin, Michael E., Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M., Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N., Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert H.M., Molenaar, I. Quintus, Borel Rinkes, Inne H., Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J., Iacobuzio-Donahue, Christine, Leach, Steven D., Pappin, Darryl J., Hammell, Molly, Klimstra, David S., Basturk, Olca, Hruban, Ralph H., Offerhaus, George Johan, Vries, Robert G.J., Clevers, Hans, Tuveson, David A.

Volltext

Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals von Maimets, Martti, Rocchi, Cecilia, Bron, Reinier, Pringle, Sarah, Kuipers, Jeroen, Giepmans, Ben N.G., Vries, Robert G.J., Clevers, Hans, de Haan, Gerald, van Os, Ronald, Coppes, Robert P.

Volltext

Correction: The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis von Mahmoudi, Tokameh, Boj, Sylvia F, Hatzis, Pantelis, Li, Vivian S W, Taouatas, Nadia, Vries, Robert G J, Teunissen, Hans, Begthel, Harry, Korving, Jeroen, Mohammed, Shabaz, Heck, Albert J R, Clevers, Hans

Volltext

Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors von Patel, Jashmin, McLeod, Laura E., Vries, Robert G. J., Flynn, Andrea, Wang, Xuemin, Proud, Christopher G.

Volltext