Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice von Hancock, Laura A., Hennessy, Corinne E., Solomon, George M., Dobrinskikh, Evgenia, Estrella, Alani, Hara, Naoko, Hill, David B., Kissner, William J., Markovetz, Matthew R., Grove Villalon, Diane E., Voss, Matthew E., Tearney, Guillermo J., Carroll, Kate S., Shi, Yunlong, Schwarz, Marvin I., Thelin, William R., Rowe, Steven M., Yang, Ivana V., Evans, Christopher M., Schwartz, David A.

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Enantioselective Synthesis of Benzyl (1S,2R,4R)-4-(tert-Butoxycarbonylamino)-2-(hydroxymethyl)cyclohexylcarbamate Using an Iodolactamization As the Key Step von Campbell, Carlton L, Hassler, Carla, Ko, Soo S, Voss, Matthew E, Guaciaro, Michael A, Carter, Percy H, Cherney, Robert J

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Discovery of MK-4688: an Efficient Inhibitor of the HDM2–p53 Protein–Protein Interaction von Reutershan, Michael H, Machacek, Michelle R, Altman, Michael D, Bogen, Stephane, Cai, Mingmei, Cammarano, Carolyn, Chen, Dapeng, Christopher, Matthew, Cryan, John, Daublain, Pierre, Fradera, Xavier, Geda, Prasanthi, Goldenblatt, Peter, Hill, Armetta D, Kemper, Raymond A, Kutilek, Victoria, Li, Chaomin, Martinez, Michelle, McCoy, Mark, Nair, Latha, Pan, Weidong, Thompson, Christopher F, Scapin, Giovanna, Shizuka, Manami, Spatz, Marianne L, Steinhuebel, Dietrich, Sun, Binyuan, Voss, Matthew E, Wang, Xiao, Yang, Liping, Yeh, Tammie C, Dussault, Isabelle, Marshall, C. Gary, Trotter, B. Wesley

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Photochemically Enhanced Binding of Small Molecules to the Tumor Necrosis Factor Receptor-1 Inhibits the Binding of TNF-α von Carter, Percy H., Scherle, Peggy A., Muckelbauer, Jodi A., Voss, Matthew E., Liu, Rui-Qin, Thompson, Lorin A., Tebben, Andrew J., Solomon, Kimberly A., Lo, Yvonne C., Li, Zhong, Strzemienski, Paul, Yang, Gengjie, Falahatpisheh, Nikoo, Xu, Meizhong, Wu, Zhongren, Farrow, Neil A., Ramnarayan, Kal, Wang, Jing, Rideout, Darryl, Yalamoori, Venkatachalapathi, Domaille, Peter, Underwood, Dennis J., Trzaskos, James M., Friedman, Steven M., Newton, Robert C., Decicco, Carl P.

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A simple and convenient one-pot method for the preparation of heteroaryl-2-imidazoles from nitriles von Voss, Matthew E., Beer, Catherine M., Mitchell, Scott A., Blomgren, Peter A., Zhichkin, Paul E.

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Synthesis and SAR studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off-target kinase selectivity von Voss, Matthew E., Rainka, Matthew P., Fleming, Mike, Peterson, Lisa H., Belanger, David B., Siddiqui, M. Arshad, Hruza, Alan, Voigt, Johannes, Gray, Kimberly, Basso, Andrea D.

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Synthesis and SAR of vinca alkaloid analogues von Voss, Matthew E., Ralph, Jeffery M., Xie, Dejian, Manning, David D., Chen, Xinchao, Frank, Anthony J., Leyhane, Andrew J., Liu, Lei, Stevens, Jason M., Budde, Cheryl, Surman, Matthew D., Friedrich, Thomas, Peace, Denise, Scott, Ian L., Wolf, Mark, Johnson, Randall

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Discovery of an orally-bioavailable CC Chemokine Receptor 2 antagonist derived from an acyclic diaminoalcohol backbone von Carter, Percy H., Brown, Gregory D., King, Sarah R., Voss, Matthew E., Tebben, Andrew J., Cherney, Robert J., Mandlekar, Sandhya, Lo, Yvonne C., Yang, Gengjie, Miller, Persymphonie B., Scherle, Peggy A., Zhao, Qihong, Decicco, Carl P.

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γ-Lactams as glycinamide replacements in cyclohexane-based CC chemokine receptor 2 (CCR2) antagonists von Cherney, Robert J., Mo, Ruowei, Meyer, Dayton T., Voss, Matthew E., Yang, Michael G., Santella, Joseph B., Duncia, John V., Lo, Yvonne C., Yang, Gengjie, Miller, Persymphonie B., Scherle, Peggy A., Zhao, Qihong, Mandlekar, Sandhya, Cvijic, Mary Ellen, Barrish, Joel C., Decicco, Carl P., Carter, Percy H.

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Novel sulfone-containing di- and trisubstituted cyclohexanes as potent CC chemokine receptor 2 (CCR2) antagonists von Cherney, Robert J., Mo, Ruowei, Meyer, Dayton T., Voss, Matthew E., Lo, Yvonne C., Yang, Gengjie, Miller, Persymphonie B., Scherle, Peggy A., Tebben, Andrew J., Carter, Percy H., Decicco, Carl P.

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Design, Synthesis, and Structure−Activity Relationships of Macrocyclic Hydroxamic Acids That Inhibit Tumor Necrosis Factor α Release in Vitro and in Vivo von Xue, Chu-Biao, Voss, Matthew E, Nelson, David J, Duan, James J.-W, Cherney, Robert J, Jacobson, Irina C, He, Xiaohua, Roderick, John, Chen, Lihua, Corbett, Ronald L, Wang, Li, Meyer, Dayton T, Kennedy, Kenneth, DeGrado, William F, Hardman, Karl D, Teleha, Christopher A, Jaffee, Bruce D, Liu, Rui-Qin, Copeland, Robert A, Covington, Maryanne B, Christ, David D, Trzaskos, James M, Newton, Robert C, Magolda, Ronald L, Wexler, Ruth R, Decicco, Carl P

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Design, Synthesis, and Evaluation of Benzothiadiazepine Hydroxamates as Selective Tumor Necrosis Factor-α Converting Enzyme Inhibitors von Cherney, Robert J, Duan, James J.-W, Voss, Matthew E, Chen, Lihua, Wang, Li, Meyer, Dayton T, Wasserman, Zelda R, Hardman, Karl D, Liu, Rui-Qin, Covington, Maryanne B, Qian, Mingxin, Mandlekar, Sandhya, Christ, David D, Trzaskos, James M, Newton, Robert C, Magolda, Ronald L, Wexler, Ruth R, Decicco, Carl P

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Both 5-arylidene-2-thioxodihydropyrimidine-4,6(1H, 5H)-diones and 3-thioxo-2,3-dihydro-1H-imidazo[1,5-a]indol-1-ones are light-dependent tumor necrosis factor-α antagonists von VOSS, Matthew E, CARTER, Percy H, STRZEMIENSKI, Paul, EVERLOF, J. Gerry, TRZASKOS, James M, DECICCO, Carl P, TEBBEN, Andrew J, SCHERLE, Peggy A, BROWN, Gregory D, THOMPSON, Lorin A, MEIZHONG XU, LO, Yvonne C, YANG, Gengjie, LIU, Rui-Qin

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Application of Isayama–Mukaiyama cobalt catalyzed hydroperoxysilylation for the preparation of ritonavir hydroperoxide von Gazal, Sharon, Gupta, Priya, Gunturu, Siva Ramakrishna, Isherwood, Matthew, Voss, Matthew E.

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Synthetic studies directed toward naturally occurring cyclooctanoids. 1. A total synthesis of (.+-.)-ceroplastol I von Boeckman, Robert K, Arvanitis, Argyrios, Voss, Matthew E

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Design and synthesis of a protein .beta.-turn mimetic von Olson, Gary L, Voss, Matthew E, Hill, David E, Kahn, Michael, Madison, Vincent S, Cook, Charles M

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Preparation of 9,9-Disubstituted 4,5-Diazafluorenes Useful as Cognitive Enhancers von Costello, Timothy D, Jensen, James H, Teleha, Christopher A, Voss, Matthew E

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Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-[alpha] von Carter, Percy H., Scherle, Peggy A., Muckelbauer, Jodi K., Voss, Matthew E., Liu, Rui-qin, Thompson III, Lorin A., Xu, Meizhong, Lo, Yvonne C., Li, Zhong, Strzemienski, Paul, Yang, Gengjie, Falahatpishen, Nikoo, Farrow, Neil A., Tebben, Andrew J., Underwood, Denis, Trzaskos, James M., Friedman, Steven M., Newton, Robert C., Decicco, Carl P.

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Concepts and progress in the development of peptide mimetics von Olson, Gary L, Bolin, David R, Bonner, Mary Pat, Bos, Michael, Cook, Charles M, Fry, David C, Graves, Bradford J, Hatada, Marcos, Hill, David E

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g-Lactams as glycinamide replacements in cyclohexane-based CC chemokine receptor 2 (CCR2) antagonists von Cherney, Robert J, Mo, Ruowei, Meyer, Dayton T, Voss, Matthew E, Yang, Michael G, Santella, Joseph B, Duncia, John V, Lo, Yvonne C, Yang, Gengjie, Miller, Persymphonie B, Scherle, Peggy A, Zhao, Qihong, Mandlekar, Sandhya, Cvijic, Mary Ellen, Barrish, Joel C, Decicco, Carl P, Carter, Percy H

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