Dnmt3a and Dnmt3b Associate with Enhancers to Regulate Human Epidermal Stem Cell Homeostasis von Rinaldi, Lorenzo, Datta, Debayan, Serrat, Judit, Morey, Lluis, Solanas, Guiomar, Avgustinova, Alexandra, Blanco, Enrique, Pons, José Ignacio, Matallanas, David, Von Kriegsheim, Alex, Di Croce, Luciano, Benitah, Salvador Aznar

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Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration von Bolado-Carrancio, Alfonso, Rukhlenko, Oleksii S., Nikonova, Elena, Tsyganov, Mikhail A., Wheeler, Anne, Garcia-Munoz, Amaya, Kolch, Walter, von Kriegsheim, Alex, Kholodenko, Boris N.

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Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism von Ryan, Dylan Gerard, Yang, Ming, Prag, Hiran A, Blanco, Giovanny Rodriguez, Nikitopoulou, Efterpi, Segarra-Mondejar, Marc, Powell, Christopher A, Young, Tim, Burger, Nils, Miljkovic, Jan Lj, Minczuk, Michal, Murphy, Michael P, von Kriegsheim, Alex, Frezza, Christian

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Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of Sotorasib von Nolan, Aoife, Raso, Cinzia, Kolch, Walter, Kriegsheim, Alex von, Wynne, Kieran, Matallanas, David

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Regulation of IL-1β–induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways von Scholz, Carsten C., Cavadas, Miguel A. S., Tambuwala, Murtaza M., Hams, Emily, Rodríguez, Javier, von Kriegsheim, Alex, Cotter, Philip, Bruning, Ulrike, Fallon, Padraic G., Cheong, Alex, Cummins, Eoin P., Taylor, Cormac T.

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Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons von Macdonald, Lewis, Taylor, Gillian C, Brisbane, Jennifer Margaret, Christodoulou, Ersi, Scott, Lucy, von Kriegsheim, Alex, Rossant, Janet, Gu, Bin, Wood, Andrew J

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RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer von Hall, Adam E., Pohl, Sebastian Öther-Gee, Cammareri, Patrizia, Aitken, Stuart, Younger, Nicholas T., Raponi, Michela, Billard, Caroline V., Carrancio, Alfonso Bolado, Bastem, Aslihan, Freile, Paz, Haward, Fiona, Adams, Ian R., Caceres, Javier F., Preyzner, Paula, von Kriegsheim, Alex, Dunlop, Malcolm G., Din, Farhat V., Myant, Kevin B.

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RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways von Gudiño, Victoria, Pohl, Sebastian Öther-Gee, Billard, Caroline V., Cammareri, Patrizia, Bolado, Alfonso, Aitken, Stuart, Stevenson, David, Hall, Adam E., Agostino, Mark, Cassidy, John, Nixon, Colin, von Kriegsheim, Alex, Freile, Paz, Popplewell, Linda, Dickson, George, Murphy, Laura, Wheeler, Ann, Dunlop, Malcolm, Din, Farhat, Strathdee, Douglas, Sansom, Owen J., Myant, Kevin B.

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Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function von Haward, Fiona, Maslon, Magdalena M., Yeyati, Patricia L., Bellora, Nicolas, Hansen, Jan N., Aitken, Stuart, Lawson, Jennifer, von Kriegsheim, Alex, Wachten, Dagmar, Mill, Pleasantine, Adams, Ian R., Caceres, Javier F.

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Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways von Rodriguez, Javier, Pilkington, Ruth, Garcia Munoz, Amaya, Nguyen, Lan K., Rauch, Nora, Kennedy, Susan, Monsefi, Naser, Herrero, Ana, Taylor, Cormac T., von Kriegsheim, Alex

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iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE von Oikonomidi, Ioanna, Burbridge, Emma, Cavadas, Miguel, Sullivan, Graeme, Collis, Blanka, Naegele, Heike, Clancy, Danielle, Brezinova, Jana, Hu, Tianyi, Bileck, Andrea, Gerner, Christopher, Bolado, Alfonso, von Kriegsheim, Alex, Martin, Seamus J, Steinberg, Florian, Strisovsky, Kvido, Adrain, Colin

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Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia von Hall, Hildegard Nikki, Bengani, Hemant, Hufnagel, Robert B, Damante, Giuseppe, Ansari, Morad, Marsh, Joseph A, Grimes, Graeme R, Kriegsheim, Alex von, Moore, David, McKie, Lisa, Rahmat, Jamalia, Mio, Catia, Blyth, Moira, Keng, Wee Teik, Islam, Lily, McEntargart, Meriel, Mannens, Marcel M, Heyningen, Veronica Van, Rainger, Joe, Brooks, Brian P, FitzPatrick, David R

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Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches von Byrne, Kate M., Monsefi, Naser, Dawson, John C., Degasperi, Andrea, Bukowski-Wills, Jimi-Carlo, Volinsky, Natalia, Dobrzyński, Maciej, Birtwistle, Marc R., Tsyganov, Mikhail A., Kiyatkin, Anatoly, Kida, Katarzyna, Finch, Andrew J., Carragher, Neil O., Kolch, Walter, Nguyen, Lan K., von Kriegsheim, Alex, Kholodenko, Boris N.

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CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis von Smith, Matthew D., Harley, Margaret E., Kemp, Alain J., Wills, Jimi, Lee, Martin, Arends, Mark, von Kriegsheim, Alex, Behrends, Christian, Wilkinson, Simon

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A Novel C1q Domain-Containing Protein Isolated from the Mollusk Modiolus kurilensis Recognizing Glycans Enriched with Acidic Galactans and Mannans von Grinchenko, Andrei V., von Kriegsheim, Alex, Shved, Nikita A., Egorova, Anna E., Ilyaskina, Diana V., Karp, Tatiana D., Goncharov, Nikolay V., Petrova, Irina Y., Kumeiko, Vadim V.

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An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein von Dewari, Pooran Singh, Southgate, Benjamin, Mccarten, Katrina, Monogarov, German, O'Duibhir, Eoghan, Quinn, Niall, Tyrer, Ashley, Leitner, Marie-Christin, Plumb, Colin, Kalantzaki, Maria, Blin, Carla, Finch, Rebecca, Bressan, Raul Bardini, Morrison, Gillian, Jacobi, Ashley M, Behlke, Mark A, von Kriegsheim, Alex, Tomlinson, Simon, Krijgsveld, Jeroen, Pollard, Steven M

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Integrative modeling and analysis of signaling crosstalk reveal molecular switches coordinating Yes-associated protein transcriptional activities von Ghomlaghi, Milad, Theocharous, Mandy, Hoang, Nhan, Shin, Sung-Young, von Kriegsheim, Alex, O’ Neill, Eric, Zhang, Tao, Nguyen, Lan K.

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Rac1 and RhoA: Networks, loops and bistability von Nguyen, Lan K., Kholodenko, Boris N., von Kriegsheim, Alex

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Cell fate decisions are specified by the dynamic ERK interactome von Kalna, Gabriella, Baiocchi, Daniela, Orton, Richard, Birtwistle, Marc, Yamada, Kayo, von Kriegsheim, Alex, Morrice, Nicholas, Sumpton, David, Bienvenut, Willy, Kolch, Walter, Gilbert, David, Lamond, Angus

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Correction: A novel role of MNT as a negative regulator of REL and the NF-κB pathway von Liaño-Pons, Judit, Lafita-Navarro, M. Carmen, García-Gaipo, Lorena, Colomer, Carlota, Rodríguez, Javier, von Kriegsheim, Alex, Hurlin, Peter J., Ourique, Fabiana, Delgado, M. Dolores, Bigas, Anna, Espinosa, Lluis, León, Javier

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