PAGE: parametric analysis of gene set enrichment von Kim, Seon-Young, Volsky, David J

Volltext

Role of the macrophage in HIV-associated neurocognitive disorders and other comorbidities in patients on effective antiretroviral treatment von Rappaport, Jay, Volsky, David J.

Volltext

Innate immune responses reverse HIV cognitive disease in mice: Profile by RNAseq in the brain von Borjabad, Alejandra, Dong, Baojun, Chao, Wei, Volsky, David J, Potash, Mary Jane

Volltext

EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment von Gu, Chao-Jiang, Borjabad, Alejandra, Hadas, Eran, Kelschenbach, Jennifer, Kim, Boe-Hyun, Chao, Wei, Arancio, Ottavio, Suh, Jin, Polsky, Bruce, McMillan, JoEllyn, Edagwa, Benson, Gendelman, Howard E, Potash, Mary Jane, Volsky, David J

Volltext

Peroxisome Proliferator-Activated Receptor-gamma agonists exhibit anti-inflammatory and antiviral effects in an EcoHIV mouse model von Omeragic, Amila, Kara-Yacoubian, Nareg, Kelschenbach, Jennifer, Sahin, Cigdem, Cummins, Carolyn L., Volsky, David J., Bendayan, Reina

Volltext

Intranasal insulin therapy reverses hippocampal dendritic injury and cognitive impairment in a model of HIV-associated neurocognitive disorders in EcoHIV-infected mice von Kim, Boe-Hyun, Kelschenbach, Jennifer, Borjabad, Alejandra, Hadas, Eran, He, Hongxia, Potash, Mary Jane, Nedelcovych, Michael T, Rais, Rana, Haughey, Norman J, McArthur, Justin C, Slusher, Barbara S, Volsky, David J

Volltext

Significant effects of antiretroviral therapy on global gene expression in brain tissues of patients with HIV-1-associated neurocognitive disorders von Borjabad, Alejandra, Morgello, Susan, Chao, Wei, Kim, Seon-Young, Brooks, Andrew I, Murray, Jacinta, Potash, Mary Jane, Volsky, David J

Volltext

EcoHIV Infection of Primary Murine Brain Cell Cultures to Model HIV Replication and Neuropathogenesis von Kim, Boe-Hyun, Chao, Wei, Hadas, Eran, Borjabad, Alejandra, Potash, Mary Jane, Volsky, David J

Volltext

CCL2 is required for initiation but not persistence of HIV infection mediated neurocognitive disease in mice von Kim, Boe-Hyun, Hadas, Eran, Kelschenbach, Jennifer, Chao, Wei, Gu, Chao-Jiang, Potash, Mary Jane, Volsky, David J.

Volltext

Mechanism of Ceftriaxone Induction of Excitatory Amino Acid Transporter-2 Expression and Glutamate Uptake in Primary Human Astrocytes von Lee, Seok-Geun, Su, Zhao-Zhong, Emdad, Luni, Gupta, Pankaj, Sarkar, Devanand, Borjabad, Alejandra, Volsky, David J., Fisher, Paul B.

Volltext

Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV von Zhu, Xiaolei, Hollinger, Kristen R., Huang, Yiyao, Borjabad, Alejandra, Kim, Boe-Hyun, Arab, Tanina, Thomas, Ajit G., Moniruzzaman, Mohammed, Lovell, Lyndah, Turchinovich, Andrey, Witwer, Kenneth W., Volsky, David J., Haughey, Norman J., Slusher, Barbara S.

Volltext

Buprenorphine reverses neurocognitive impairment in EcoHIV infected mice: A potential therapy for HIV-NCI von Murphy, Aniella J, Kelschenbach, Jennifer, He, Hongxia, Chao, Wei, Kim, Boe-Hyun, Volsky, David J, Berman, Joan W

Volltext

Selective peroxisome proliferator‐activated receptor‐gamma modulator, INT131 exhibits anti‐inflammatory effects in an EcoHIV mouse model von Omeragic, Amila, Saikali, Michael F., Currier, Sydney, Volsky, David J., Cummins, Carolyn L., Bendayan, Reina

Volltext

Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1 von Kang, Dong-chul, Su, Zao-zhong, Sarkar, Devanand, Emdad, Luni, Volsky, David J., Fisher, Paul B.

Volltext

Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges von Im, Eung-Jun, Hong, Jessie P, Roshorm, Yaowaluck, Bridgeman, Anne, Létourneau, Sven, Liljeström, Peter, Potash, Mary Jane, Volsky, David J, McMichael, Andrew J, Hanke, Tomáš

Volltext

Common Transcriptional Signatures in Brain Tissue from Patients with HIV-Associated Neurocognitive Disorders, Alzheimer’s Disease, and Multiple Sclerosis von Borjabad, Alejandra, Volsky, David J.

Volltext

Glutamine Antagonist JHU083 Normalizes Aberrant Glutamate Production and Cognitive Deficits in the EcoHIV Murine Model of HIV-Associated Neurocognitive Disorders von Nedelcovych, Michael T., Kim, Boe-Hyun, Zhu, Xiaolei, Lovell, Lyndah E., Manning, Arena A., Kelschenbach, Jennifer, Hadas, Eran, Chao, Wei, Prchalová, Eva, Dash, Ranjeet P., Wu, Ying, Alt, Jesse, Thomas, Ajit G., Rais, Rana, Kamiya, Atsushi, Volsky, David J., Slusher, Barbara S.

Volltext

Efficient Expression of HIV in Immunocompetent Mouse Brain Reveals a Novel Nonneurotoxic Viral Function in Hippocampal Synaptodendritic Injury and Memory Impairment von Kelschenbach, Jennifer, He, Hongxia, Kim, Boe-Hyun, Borjabad, Alejandra, Gu, Chao-Jiang, Chao, Wei, Do, Meilan, Sharer, Leroy R, Zhang, Hong, Arancio, Ottavio, Potash, Mary Jane, Volsky, David J

Volltext

HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis von Nitkiewicz, Jadwiga, Borjabad, Alejandra, Morgello, Susan, Murray, Jacinta, Chao, Wei, Emdad, Luni, Fisher, Paul B, Potash, Mary Jane, Volsky, David J

Volltext

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization von Norman, John P, Perry, Seth W, Reynolds, Holly M, Kiebala, Michelle, De Mesy Bentley, Karen L, Trejo, Margarita, Volsky, David J, Maggirwar, Sanjay B, Dewhurst, Stephen, Masliah, Eliezer, Gelbard, Harris A

Volltext