Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension von Beuschlein, Felix, Boulkroun, Sheerazed, Osswald, Andrea, Wieland, Thomas, Nielsen, Hang N, Lichtenauer, Urs D, Penton, David, Schack, Vivien R, Amar, Laurence, Fischer, Evelyn, Walther, Anett, Tauber, Philipp, Schwarzmayr, Thomas, Diener, Susanne, Graf, Elisabeth, Allolio, Bruno, Samson-Couterie, Benoit, Benecke, Arndt, Quinkler, Marcus, Fallo, Francesco, Plouin, Pierre-Francois, Mantero, Franco, Meitinger, Thomas, Mulatero, Paolo, Jeunemaitre, Xavier, Warth, Richard, Vilsen, Bente, Zennaro, Maria-Christina, Strom, Tim M, Reincke, Martin

Volltext

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack von Lopez, Jamie A., Susanto, Olivia, Jenkins, Misty R., Lukoyanova, Natalya, Sutton, Vivien R., Law, Ruby H.P., Johnston, Angus, Bird, Catherina H., Bird, Phillip I., Whisstock, James C., Trapani, Joseph A., Saibil, Helen R., Voskoboinik, Ilia

Volltext

Photo-tethered molecular beacons for superior light-induction von Klimek, Robin, Wang, Mantian, McKenney, Vivien R, Schuman, Erin M, Heckel, Alexander

Volltext

Beyond target cell death – Granzyme serine proteases in health and disease von Nüssing, Simone, Sutton, Vivien R., Trapani, Joseph A., Parish, Ian A.

Volltext

Accelerating genomic workflows using NVIDIA Parabricks von O'Connell, Kyle A, Yosufzai, Zelaikha B, Campbell, Ross A, Lobb, Collin J, Engelken, Haley T, Gorrell, Laura M, Carlson, Thad B, Catana, Josh J, Mikdadi, Dina, Bonazzi, Vivien R, Klenk, Juergen A

Volltext

Small Molecule Inhibitors of Lymphocyte Perforin as Focused Immunosuppressants for Infection and Autoimmunity von Spicer, Julie A., Huttunen, Kristiina M., Jose, Jiney, Dimitrov, Ivo, Akhlaghi, Hedieh, Sutton, Vivien R., Voskoboinik, Ilia, Trapani, Joseph

Volltext

Environmental DNA metabarcoding for benthic monitoring: A review of sediment sampling and DNA extraction methods von Pawlowski, J., Bruce, K., Panksep, K., Aguirre, F.I., Amalfitano, S., Apothéloz-Perret-Gentil, L., Baussant, T., Bouchez, A., Carugati, L., Cermakova, K., Cordier, T., Corinaldesi, C., Costa, F.O., Danovaro, R., Dell'Anno, A., Duarte, S., Eisendle, U., Ferrari, B.J.D., Frontalini, F., Frühe, L., Haegerbaeumer, A., Kisand, V., Krolicka, A., Lanzén, A., Leese, F., Lejzerowicz, F., Lyautey, E., Maček, I., Sagova-Marečková, M., Pearman, J.K., Pochon, X., Stoeck, T., Vivien, R., Weigand, A., Fazi, S.

Volltext

Should biomedical research be like Airbnb? von Bonazzi, Vivien R, Bourne, Philip E

Volltext

CD46 Isoforms Influence the Mode of Entry by Human Herpesvirus 6A/B in T Cells von Rossen, Litten Sørensen, Schack, Vivien R, Thuesen, Katrine Kyd Holstein, Bundgaard, Bettina, Höllsberg, Per

Volltext

Neurological disease mutations of α3 Na+,K+-ATPase: Structural and functional perspectives and rescue of compromised function von Holm, Rikke, Toustrup-Jensen, Mads S., Einholm, Anja P., Schack, Vivien R., Andersen, Jens P., Vilsen, Bente

Volltext

Somatic ATP1A1, ATP2B3, and KCNJ5 Mutations in Aldosterone-Producing Adenomas von Williams, Tracy Ann, Monticone, Silvia, Schack, Vivien R, Stindl, Julia, Burrello, Jacopo, Buffolo, Fabrizio, Annaratone, Laura, Castellano, Isabella, Beuschlein, Felix, Reincke, Martin, Lucatello, Barbara, Ronconi, Vanessa, Fallo, Francesco, Bernini, Giampaolo, Maccario, Mauro, Giacchetti, Gilberta, Veglio, Franco, Warth, Richard, Vilsen, Bente, Mulatero, Paolo

Volltext

The Tetraspanin Protein CD9 Modulates Infection with Human Herpesvirus 6A and 6B in a CD46-Dependent Manner von Schack, Vivien R., Rossen, Litten Sorensen, Ekebjaerg, Clara Christina, Thuesen, Katrine Kyd Holstein, Bundgaard, Bettina, Hollsberg, Per

Volltext

From biomedical cloud platforms to microservices: next steps in FAIR data and analysis von Sheffield, Nathan C., Bonazzi, Vivien R., Bourne, Philip E., Burdett, Tony, Clark, Timothy, Grossman, Robert L., Spjuth, Ola, Yates, Andrew D.

Volltext

Comparison of electrostatic and mechanical cell sorting with limited starting material von Staunstrup, Nicklas H., Petersen, Charlotte C., Fuglsang, Tina, Starnawska, Anna, Chernomorchenko, Ana, Qvist, Per, Schack, Vivien R.

Volltext

Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block in vitro granzyme-mediated target cell killing by CD8 T or NK cells von Sutton, Vivien R, Watt, Sally V, Akhlaghi, Hedieh, Cipolla, David C, Chen, Kuan-Ju, LaSala, Daniel, McDonald, Patrick P, Beavis, Paul A, Munoz, Isabelle, Hodel, Adrian W, Noori, Tahereh, Voskoboinik, Ilia, Trapani, Joseph A

Volltext

Antigen‐specific CD4+CD25+ T cells induced by locally expressed ICOS‐Ig: the role of Foxp3, Perforin, Granzyme B and IL‐10 ‐ an experimental study von Christiansen, Dale, Mouhtouris, Effie, Hodgson, Russell, Sutton, Vivien R., Trapani, Joseph A., Ierino, Francesco L., Sandrin, Mauro S.

Volltext

Severely impaired CTL killing is a feature of the neurological disorder Niemann-Pick disease type C1 von Castiblanco, Daniela, Rudd-Schmidt, Jesse A., Noori, Tahereh, Sutton, Vivien R., Hung, Ya Hui, Flinsenberg, Thijs W.H., Hodel, Adrian W., Young, Neil D., Smith, Nicholas, Bratkovic, Drago, Peters, Heidi, Walterfang, Mark, Trapani, Joseph A., Brennan, Amelia J., Voskoboinik, Ilia

Volltext

Novel homozygous CD46 variant with C‐isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome von Schack, Vivien R., Herlin, Morten K., Pedersen, Henrik, Jensen, J. Magnus Bernth, Færch, Mia, Bundgaard, Bettina, Jensen, Rasmus K., Jensen, Uffe B., Christensen, Rikke, Andersen, Gregers R., Thiel, Steffen, Höllsberg, Per

Volltext

Relationship between Intracellular Na+ Concentration and Reduced Na+ Affinity in Na+,K+-ATPase Mutants Causing Neurological Disease von Toustrup-Jensen, Mads S., Einholm, Anja P., Schack, Vivien R., Nielsen, Hang N., Holm, Rikke, Sobrido, María-Jesús, Andersen, Jens P., Clausen, Torben, Vilsen, Bente

Volltext

Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase von Roenn, Christian P., Li, Melody, Schack, Vivien R., Forster, Ian C., Holm, Rikke, Toustrup-Jensen, Mads S., Andersen, Jens P., Petrou, Steven, Vilsen, Bente

Volltext