Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology von Izco, María, Blesa, Javier, Schleef, Martin, Schmeer, Marco, Porcari, Riccardo, Al-Shawi, Raya, Ellmerich, Stephan, de Toro, María, Gardiner, Chris, Seow, Yiqi, Reinares-Sebastian, Alejandro, Forcen, Raquel, Simons, J. Paul, Bellotti, Vittorio, Cooper, J. Mark, Alvarez-Erviti, Lydia

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Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis von Slamova, Ivana, Adib, Rozita, Ellmerich, Stephan, Golos, Michal R., Gilbertson, Janet A., Botcher, Nicola, Canetti, Diana, Taylor, Graham W., Rendell, Nigel, Tennent, Glenys A., Verona, Guglielmo, Porcari, Riccardo, Mangione, P. Patrizia, Gillmore, Julian D., Pepys, Mark B., Bellotti, Vittorio, Hawkins, Philip N., Al-Shawi, Raya, Simons, J. Paul

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L444P Gba1 mutation increases formation and spread of alpha-synuclein deposits in mice injected with mouse alpha-synuclein pre-formed fibrils von Migdalska-Richards, Anna, Wegrzynowicz, Michal, Harrison, Ian F., Verona, Guglielmo, Bellotti, Vittorio, Spillantini, Maria Grazia, Schapira, Anthony H.

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A Narrative Review of the Role of Transthyretin in Health and Disease von Liz, Marcia Almeida, Coelho, Teresa, Bellotti, Vittorio, Fernandez-Arias, Maria Isabel, Mallaina, Pablo, Obici, Laura

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Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity von Le Marchand, Tanguy, de Rosa, Matteo, Salvi, Nicola, Sala, Benedetta Maria, Andreas, Loren B., Barbet-Massin, Emeline, Sormanni, Pietro, Barbiroli, Alberto, Porcari, Riccardo, Sousa Mota, Cristiano, de Sanctis, Daniele, Bolognesi, Martino, Emsley, Lyndon, Bellotti, Vittorio, Blackledge, Martin, Camilloni, Carlo, Pintacuda, Guido, Ricagno, Stefano

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Breakdown of supersaturation barrier links protein folding to amyloid formation von Noji, Masahiro, Samejima, Tatsushi, Yamaguchi, Keiichi, So, Masatomo, Yuzu, Keisuke, Chatani, Eri, Akazawa-Ogawa, Yoko, Hagihara, Yoshihisa, Kawata, Yasushi, Ikenaka, Kensuke, Mochizuki, Hideki, Kardos, József, Otzen, Daniel E., Bellotti, Vittorio, Buchner, Johannes, Goto, Yuji

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Binding of Monovalent and Bivalent Ligands by Transthyretin Causes Different Short- and Long-Distance Conformational Changes von Corazza, Alessandra, Verona, Guglielmo, Waudby, Christopher A, Mangione, P. Patrizia, Bingham, Ryan, Uings, Iain, Canetti, Diana, Nocerino, Paola, Taylor, Graham W, Pepys, Mark B, Christodoulou, John, Bellotti, Vittorio

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Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils von Raimondi, Sara, Mangione, P. Patrizia, Verona, Guglielmo, Canetti, Diana, Nocerino, Paola, Marchese, Loredana, Piccarducci, Rebecca, Mondani, Valentina, Faravelli, Giulia, Taylor, Graham W., Gillmore, Julian D., Corazza, Alessandra, Pepys, Mark B., Giorgetti, Sofia, Bellotti, Vittorio

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Hereditary Systemic Amyloidosis Due to Asp76Asn Variant β2-Microglobulin von Valleix, Sophie, Gillmore, Julian D, Bridoux, Frank, Mangione, Palma P, Dogan, Ahmet, Nedelec, Brigitte, Boimard, Mathieu, Touchard, Guy, Goujon, Jean-Michel, Lacombe, Corinne, Lozeron, Pierre, Adams, David, Lacroix, Catherine, Maisonobe, Thierry, Planté-Bordeneuve, Violaine, Vrana, Julie A, Theis, Jason D, Giorgetti, Sofia, Porcari, Riccardo, Ricagno, Stefano, Bolognesi, Martino, Stoppini, Monica, Delpech, Marc, Pepys, Mark B, Hawkins, Philip N, Bellotti, Vittorio

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A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis von Marcoux, Julien, Mangione, P Patrizia, Porcari, Riccardo, Degiacomi, Matteo T, Verona, Guglielmo, Taylor, Graham W, Giorgetti, Sofia, Raimondi, Sara, Sanglier‐Cianférani, Sarah, Benesch, Justin LP, Cecconi, Ciro, Naqvi, Mohsin M, Gillmore, Julian D, Hawkins, Philip N, Stoppini, Monica, Robinson, Carol V, Pepys, Mark B, Bellotti, Vittorio

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Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases von Solomon, Miriam, Foderà, Vito, Langkilde, Annette Eva, Elliott, Perry, Tagliavini, Fabrizio, Forsyth, Trevor, Klementieva, Oxana, Bellotti, Vittorio

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Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis von Mangione, P. Patrizia, Porcari, Riccardo, Gillmore, Julian D., Pucci, Piero, Monti, Maria, Porcari, Mattia, Giorgetti, Sofia, Marchese, Loredana, Raimondi, Sara, Serpell, Louise C., Chen, Wenjie, Relini, Annalisa, Marcoux, Julien, Clatworthy, Innes R., Taylor, Graham W., Tennent, Glenys A., Robinson, Carol V., Hawkins, Philip N., Stoppini, Monica, Wood, Stephen P., Pepys, Mark B., Bellotti, Vittorio

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Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic β2-microglobulin variant von Domanska, Katarzyna, Vanderhaegen, Saskia, Srinivasan, Vasundara, Pardon, Els, Dupeux, Florine, Marquez, Jose A, Giorgetti, Sofia, Stoppini, Monica, Wyns, Lode, Bellotti, Vittorio, Steyaert, Jan

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Targeting C-reactive protein for the treatment of cardiovascular disease von Ruth Gallimore, J, Pepys, Mark B, Polara, Alessandra, Hirschfield, Gideon M, Smith, Martin D, Wood, Stephen P, Sharif, Isam, Gray, Gillian A, Sabin, Caroline A, Bellotti, Vittorio, Myers, Rebecca M, Andrew Aquilina, J, Ley, Steven V, Thompson, Darren, Hawkins, Philip N, Robinson, Carol V, Kolstoe, Simon E, Kahan, Melvyn C, Cobb, Alexander J. A, Tennent, Glenys A, Jenvey, Michelle C

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Systemic Amyloidosis: Lessons from β2-Microglobulin von Stoppini, Monica, Bellotti, Vittorio

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D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile von Valleix, Sophie, Verona, Guglielmo, Jourde-Chiche, Noémie, Nédelec, Brigitte, Mangione, P. Patrizia, Bridoux, Frank, Mangé, Alain, Dogan, Ahmet, Goujon, Jean-Michel, Lhomme, Marie, Dauteuille, Carolane, Chabert, Michèle, Porcari, Riccardo, Waudby, Christopher A., Relini, Annalisa, Talmud, Philippa J., Kovrov, Oleg, Olivecrona, Gunilla, Stoppini, Monica, Christodoulou, John, Hawkins, Philip N., Grateau, Gilles, Delpech, Marc, Kontush, Anatol, Gillmore, Julian D., Kalopissis, Athina D., Bellotti, Vittorio

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Assessment of Cellular Responses after Short- and Long-Term Exposure to Silver Nanoparticles in Human Neuroblastoma (SH-SY5Y) and Astrocytoma (D384) Cells von De Simone, Uliana, Bellotti, Vittorio, Manzo, Luigi, Coccini, Teresa

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Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin von Cantarutti, Cristina, Raimondi, Sara, Brancolini, Giorgia, Corazza, Alessandra, Giorgetti, Sofia, Ballico, Maurizio, Zanini, Stefano, Palmisano, Giovanni, Bertoncin, Paolo, Marchese, Loredana, Patrizia Mangione, P, Bellotti, Vittorio, Corni, Stefano, Fogolari, Federico, Esposito, Gennaro

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Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro von Ozawa, Daisaku, Nomura, Ryo, Mangione, P. Patrizia, Hasegawa, Kazuhiro, Okoshi, Tadakazu, Porcari, Riccardo, Bellotti, Vittorio, Naiki, Hironobu

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Clinical Amyloid Typing by Proteomics: Performance Evaluation and Data Sharing between Two Centres von Canetti, Diana, Brambilla, Francesca, Rendell, Nigel B., Nocerino, Paola, Gilbertson, Janet A., Di Silvestre, Dario, Bergamaschi, Andrea, Lavatelli, Francesca, Merlini, Giampaolo, Gillmore, Julian D., Bellotti, Vittorio, Mauri, Pierluigi, Taylor, Graham W.

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