Chimira: analysis of small RNA sequencing data and microRNA modifications von Vitsios, Dimitrios M, Enright, Anton J

Volltext

Prioritizing non-coding regions based on human genomic constraint and sequence context with deep learning von Vitsios, Dimitrios, Dhindsa, Ryan S., Middleton, Lawrence, Gussow, Ayal B., Petrovski, Slavé

Volltext

mRNA 3′ uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome von Morgan, Marcos, Much, Christian, DiGiacomo, Monica, Azzi, Chiara, Ivanova, Ivayla, Vitsios, Dimitrios M., Pistolic, Jelena, Collier, Paul, Moreira, Pedro N., Benes, Vladimir, Enright, Anton J., O’Carroll, Dónal

Volltext

Large-scale analysis of microRNA expression, epi-transcriptomic features and biogenesis von Vitsios, Dimitrios M, Davis, Matthew P, van Dongen, Stijn, Enright, Anton J

Volltext

Mirnovo: genome-free prediction of microRNAs from small RNA sequencing data and single-cells using decision forests von Vitsios, Dimitrios M, Kentepozidou, Elissavet, Quintais, Leonor, Benito-Gutiérrez, Elia, van Dongen, Stijn, Davis, Matthew P, Enright, Anton J

Volltext

RNA-sequencing analysis of umbilical cord plasma microRNAs from healthy newborns von Brennan, Gary P, Vitsios, Dimitrios M, Casey, Sophie, Looney, Ann-Marie, Hallberg, Boubou, Henshall, David C, Boylan, Geraldine B, Murray, Deirdre M, Mooney, Catherine

Volltext

BioPAXViz: a cytoscape application for the visual exploration of metabolic pathway evolution von Psomopoulos, Fotis E, Vitsios, Dimitrios M, Baichoo, Shakuntala, Ouzounis, Christos A

Volltext

BioPAXViz: a cytoscape application for the visual exploration of metabolic pathway evolution von Psomopoulos, Fotis E, Vitsios, Dimitrios M, Baichoo, Shakuntala, Ouzounis, Christos A

Volltext

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering von Wu, Qianxin, Ferry, Quentin R. V., Baeumler, Toni A., Michaels, Yale S., Vitsios, Dimitrios M., Habib, Omer, Arnold, Roland, Jiang, Xiaowei, Maio, Stefano, Steinkraus, Bruno R., Tapia, Marta, Piazza, Paolo, Xu, Ni, Holländer, Georg A., Milne, Thomas A., Kim, Jin-Soo, Enright, Anton J., Bassett, Andrew R., Fulga, Tudor A.

Volltext

Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis von Dhindsa, Ryan S., Mattsson, Johan, Nag, Abhishek, Wang, Quanli, Wain, Louise V., Allen, Richard, Wigmore, Eleanor M., Ibanez, Kristina, Vitsios, Dimitrios, Deevi, Sri V. V., Wasilewski, Sebastian, Karlsson, Maria, Lassi, Glenda, Olsson, Henric, Muthas, Daniel, Monkley, Susan, Mackay, Alex, Murray, Lynne, Young, Simon, Haefliger, Carolina, Maher, Toby M., Belvisi, Maria G., Jenkins, Gisli, Molyneaux, Philip L., Platt, Adam, Petrovski, Slavé

Volltext

DrugnomeAI is an ensemble machine-learning framework for predicting druggability of candidate drug targets von Raies, Arwa, Tulodziecka, Ewa, Stainer, James, Middleton, Lawrence, Dhindsa, Ryan S., Hill, Pamela, Engkvist, Ola, Harper, Andrew R., Petrovski, Slavé, Vitsios, Dimitrios

Volltext

Author Correction: DrugnomeAI is an ensemble machine-learning framework for predicting druggability of candidate drug targets von Raies, Arwa, Tulodziecka, Ewa, Stainer, James, Middleton, Lawrence, Dhindsa, Ryan S., Hill, Pamela, Engkvist, Ola, Harper, Andrew R., Petrovski, Slavé, Vitsios, Dimitrios

Volltext

Mantis-ml: Disease-Agnostic Gene Prioritization from High-Throughput Genomic Screens by Stochastic Semi-supervised Learning von Vitsios, Dimitrios, Petrovski, Slavé

Volltext

Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A von Steward, Charles A., Roovers, Jolien, Suner, Marie-Marthe, Gonzalez, Jose M., Uszczynska-Ratajczak, Barbara, Pervouchine, Dmitri, Fitzgerald, Stephen, Viola, Margarida, Stamberger, Hannah, Hamdan, Fadi F., Ceulemans, Berten, Leroy, Patricia, Nava, Caroline, Lepine, Anne, Tapanari, Electra, Keiller, Don, Abbs, Stephen, Sanchis-Juan, Alba, Grozeva, Detelina, Rogers, Anthony S., Diekhans, Mark, Guigó, Roderic, Petryszak, Robert, Minassian, Berge A., Cavalleri, Gianpiero, Vitsios, Dimitrios, Petrovski, Slavé, Harrow, Jennifer, Flicek, Paul, Lucy Raymond, F., Lench, Nicholas J., Jonghe, Peter De, Mudge, Jonathan M., Weckhuysen, Sarah, Sisodiya, Sanjay M., Frankish, Adam

Volltext

Gene-SCOUT: identifying genes with similar continuous trait fingerprints from phenome-wide association analyses von Middleton, Lawrence, Harper, Andrew R, Nag, Abhishek, Wang, Quanli, Reznichenko, Anna, Vitsios, Dimitrios, Petrovski, Slavé

Volltext

A minimal role for synonymous variation in human disease von Dhindsa, Ryan S., Wang, Quanli, Vitsios, Dimitrios, Burren, Oliver S., Hu, Fengyuan, DiCarlo, James E., Kruglyak, Leonid, MacArthur, Daniel G., Hurles, Matthew E., Petrovski, Slavé

Volltext

Disease prediction with multi-omics and biomarkers empowers case–control genetic discoveries in the UK Biobank von Garg, Manik, Karpinski, Marcin, Matelska, Dorota, Middleton, Lawrence, Burren, Oliver S., Hu, Fengyuan, Wheeler, Eleanor, Smith, Katherine R., Fabre, Margarete A., Mitchell, Jonathan, O’Neill, Amanda, Ashley, Euan A., Harper, Andrew R., Wang, Quanli, Dhindsa, Ryan S., Petrovski, Slavé, Vitsios, Dimitrios

Volltext

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis von Morgan, Marcos, Kabayama, Yuka, Much, Christian, Ivanova, Ivayla, Di Giacomo, Monica, Auchynnikava, Tatsiana, Monahan, Jack Michael, Vitsios, Dimitrios Michael, Vasiliauskaitė, Lina, Comazzetto, Stefano, Rappsilber, Juri, Allshire, Robin Campbell, Porse, Bo Torben, Enright, Anton James, O’Carroll, Dónal

Volltext

Effects of protein-coding variants on blood metabolite measurements and clinical biomarkers in the UK Biobank von Nag, Abhishek, Dhindsa, Ryan S., Middleton, Lawrence, Jiang, Xiao, Vitsios, Dimitrios, Wigmore, Eleanor, Allman, Erik L., Reznichenko, Anna, Carss, Keren, Smith, Katherine R., Wang, Quanli, Challis, Benjamin, Paul, Dirk S., Harper, Andrew R., Petrovski, Slavé

Volltext

Exome-Based Rare-Variant Analyses in CKD von Cameron-Christie, Sophia, Wolock, Charles J, Groopman, Emily, Petrovski, Slavé, Kamalakaran, Sitharthan, Povysil, Gundula, Vitsios, Dimitrios, Zhang, Mengqi, Fleckner, Jan, March, Ruth E, Gelfman, Sahar, Marasa, Maddalena, Li, Yifu, Sanna-Cherchi, Simone, Kiryluk, Krzysztof, Allen, Andrew S, Fellström, Bengt C, Haefliger, Carolina, Platt, Adam, Goldstein, David B, Gharavi, Ali G

Volltext