Selective Blockade of MicroRNA Processing by Lin28 von Viswanathan, Srinivas R, Daley, George Q, Gregory, Richard I

Volltext

Lin28: A MicroRNA Regulator with a Macro Role von Viswanathan, Srinivas R., Daley, George Q.

Volltext

Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing von Viswanathan, Srinivas R., Ha, Gavin, Hoff, Andreas M., Wala, Jeremiah A., Carrot-Zhang, Jian, Whelan, Christopher W., Haradhvala, Nicholas J., Freeman, Samuel S., Reed, Sarah C., Rhoades, Justin, Polak, Paz, Cipicchio, Michelle, Wankowicz, Stephanie A., Wong, Alicia, Kamath, Tushar, Zhang, Zhenwei, Gydush, Gregory J., Rotem, Denisse, Love, J. Christopher, Getz, Gad, Gabriel, Stacey, Zhang, Cheng-Zhong, Dehm, Scott M., Nelson, Peter S., Van Allen, Eliezer M., Choudhury, Atish D., Adalsteinsson, Viktor A., Beroukhim, Rameen, Taplin, Mary-Ellen, Meyerson, Matthew

Volltext

How splicing confers treatment resistance in prostate cancer von Konda, Prathyusha, Viswanathan, Srinivas R

Volltext

TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism von Alesi, Nicola, Akl, Elie W., Khabibullin, Damir, Liu, Heng-Jia, Nidhiry, Anna S., Garner, Emma R., Filippakis, Harilaos, Lam, Hilaire C., Shi, Wei, Viswanathan, Srinivas R., Morroni, Manrico, Ferguson, Shawn M., Henske, Elizabeth P.

Volltext

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway von Viswanathan, Vasanthi S., Ryan, Matthew J., Dhruv, Harshil D., Gill, Shubhroz, Eichhoff, Ossia M., Seashore-Ludlow, Brinton, Kaffenberger, Samuel D., Eaton, John K., Shimada, Kenichi, Aguirre, Andrew J., Viswanathan, Srinivas R., Chattopadhyay, Shrikanta, Tamayo, Pablo, Yang, Wan Seok, Rees, Matthew G., Chen, Sixun, Boskovic, Zarko V., Javaid, Sarah, Huang, Cherrie, Wu, Xiaoyun, Tseng, Yuen-Yi, Roider, Elisabeth M., Gao, Dong, Cleary, James M., Wolpin, Brian M., Mesirov, Jill P., Haber, Daniel A., Engelman, Jeffrey A., Boehm, Jesse S., Kotz, Joanne D., Hon, Cindy S., Chen, Yu, Hahn, William C., Levesque, Mitchell P., Doench, John G., Berens, Michael E., Shamji, Alykhan F., Clemons, Paul A., Stockwell, Brent R., Schreiber, Stuart L.

Volltext

Genome-guided discovery of cancer therapeutic targets von Konda, Prathyusha, Garinet, Simon, Van Allen, Eliezer M., Viswanathan, Srinivas R.

Volltext

Prostate cancer reactivates developmental epigenomic programs during metastatic progression von Pomerantz, Mark M., Qiu, Xintao, Zhu, Yanyun, Takeda, David Y., Pan, Wenting, Baca, Sylvan C., Gusev, Alexander, Korthauer, Keegan D., Severson, Tesa M., Ha, Gavin, Viswanathan, Srinivas R., Seo, Ji-Heui, Nguyen, Holly M., Zhang, Baohui, Pasaniuc, Bogdan, Giambartolomei, Claudia, Alaiwi, Sarah A., Bell, Connor A., O’Connor, Edward P., Chabot, Matthew S., Stillman, David R., Lis, Rosina, Font-Tello, Alba, Li, Lewyn, Cejas, Paloma, Bergman, Andries M., Sanders, Joyce, van der Poel, Henk G., Gayther, Simon A., Lawrenson, Kate, Fonseca, Marcos A. S., Reddy, Jessica, Corona, Rosario I., Martovetsky, Gleb, Egan, Brian, Choueiri, Toni, Ellis, Leigh, Garraway, Isla P., Lee, Gwo-Shu Mary, Corey, Eva, Long, Henry W., Zwart, Wilbert, Freedman, Matthew L.

Volltext

Determinants of MicroRNA Processing Inhibition by the Developmentally Regulated RNA-binding Protein Lin28 von Piskounova, Elena, Viswanathan, Srinivas R., Janas, Maja, LaPierre, Robert J., Daley, George Q., Sliz, Piotr, Gregory, Richard I.

Volltext

A role for Lin28 in primordial germ-cell development and germ-cell malignancy von West, Jason A., Viswanathan, Srinivas R., Yabuuchi, Akiko, Cunniff, Kerianne, Takeuchi, Ayumu, Park, In-Hyun, Sero, Julia E., Zhu, Hao, Perez-Atayde, Antonio, Frazier, A. Lindsay, Surani, M. Azim, Daley, George Q.

Volltext

Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies von Zhu, Hao, Shah, Samar, Shyh-Chang, Ng, Shinoda, Gen, Einhorn, William S, Viswanathan, Srinivas R, Takeuchi, Ayumu, Grasemann, Corinna, Rinn, John L, Lopez, Mary F, Hirschhorn, Joel N, Palmert, Mark R, Daley, George Q

Volltext

Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma von Bakouny, Ziad, Braun, David A., Shukla, Sachet A., Pan, Wenting, Gao, Xin, Hou, Yue, Flaifel, Abdallah, Tang, Stephen, Bosma-Moody, Alice, He, Meng Xiao, Vokes, Natalie, Nyman, Jackson, Xie, Wanling, Nassar, Amin H., Abou Alaiwi, Sarah, Flippot, Ronan, Bouchard, Gabrielle, Steinharter, John A., Nuzzo, Pier Vitale, Ficial, Miriam, Sant’Angelo, Miriam, Forman, Juliet, Berchuck, Jacob E., Dudani, Shaan, Bi, Kevin, Park, Jihye, Camp, Sabrina, Sticco-Ivins, Maura, Hirsch, Laure, Baca, Sylvan C., Wind-Rotolo, Megan, Ross-Macdonald, Petra, Sun, Maxine, Lee, Gwo-Shu Mary, Chang, Steven L., Wei, Xiao X., McGregor, Bradley A., Harshman, Lauren C., Genovese, Giannicola, Ellis, Leigh, Pomerantz, Mark, Hirsch, Michelle S., Freedman, Matthew L., Atkins, Michael B., Wu, Catherine J., Ho, Thai H., Linehan, W. Marston, McDermott, David F., Heng, Daniel Y. C., Viswanathan, Srinivas R., Signoretti, Sabina, Van Allen, Eliezer M., Choueiri, Toni K.

Volltext

Lin28 promotes transformation and is associated with advanced human malignancies von Viswanathan, Srinivas R, Powers, John T, Einhorn, William, Hoshida, Yujin, Ng, Tony L, Toffanin, Sara, O'Sullivan, Maureen, Lu, Jun, Phillips, Letha A, Lockhart, Victoria L, Shah, Samar P, Tanwar, Pradeep S, Mermel, Craig H, Beroukhim, Rameen, Azam, Mohammad, Teixeira, Jose, Meyerson, Matthew, Hughes, Timothy P, Llovet, Josep M, Radich, Jerald, Mullighan, Charles G, Golub, Todd R, Sorensen, Poul H, Daley, George Q

Volltext

Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study von Bendapudi, Pavan K, Dr, Hurwitz, Shelley, PhD, Fry, Ashley, MD, Marques, Marisa B, MD, Waldo, Stephen W, MD, Li, Ang, MD, Sun, Lova, MD, Upadhyay, Vivek, MD, Hamdan, Ayad, MD, Brunner, Andrew M, MD, Gansner, John M, MD, Viswanathan, Srinivas, MD, Kaufman, Richard M, MD, Uhl, Lynne, MD, Stowell, Christopher P, MD, Dzik, Walter H, MD, Makar, Robert S, MD

Volltext

Immune Checkpoint Therapy Combinations in Adult Advanced MiT Family Translocation Renal Cell Carcinomas von Alhalabi, Omar, Thouvenin, Jonathan, Négrier, Sylvie, Vano, Yann-Alexandre, Campedel, Luca, Hasanov, Elshad, Bakouny, Ziad, Hahn, Andrew W, Bilen, Mehmet Asim, Msaouel, Pavlos, Choueiri, Toni K, Viswanathan, Srinivas R, Sircar, Kanishka, Albiges, Laurence, Malouf, Gabriel G, Tannir, Nizar M

Volltext

A genetic basis for sex differences in Xp11 translocation renal cell carcinoma von Achom, Mingkee, Sadagopan, Ananthan, Bao, Chunyang, McBride, Fiona, Li, Jiao, Konda, Prathyusha, Tourdot, Richard W., Xu, Qingru, Nakhoul, Maria, Gallant, Daniel S., Ahmed, Usman Ali, O’Toole, Jillian, Freeman, Dory, Lee, Gwo-Shu Mary, Hecht, Jonathan L., Kauffman, Eric C., Einstein, David J., Choueiri, Toni K., Zhang, Cheng-Zhong, Viswanathan, Srinivas R.

Volltext

microRNA expression during trophectoderm specification von Viswanathan, Srinivas R, Mermel, Craig H, Lu, Jun, Lu, Chi-Wei, Golub, Todd R, Daley, George Q

Volltext

Integrative clinical and molecular characterization of translocation renal cell carcinoma von Bakouny, Ziad, Sadagopan, Ananthan, Ravi, Praful, Metaferia, Nebiyou Y, Li, Jiao, AbuHammad, Shatha, Tang, Stephen, Denize, Thomas, Garner, Emma R, Gao, Xin, Braun, David A, Hirsch, Laure, Steinharter, John A, Bouchard, Gabrielle, Walton, Emily, West, Destiny, Labaki, Chris, Dudani, Shaan, Gan, Chun-Loo, Sethunath, Vidyalakshmi, Carvalho, Filipe L F, Imamovic, Alma, Ricker, Cora, Vokes, Natalie I, Nyman, Jackson, Berchuck, Jacob E, Park, Jihye, Hirsch, Michelle S, Haq, Rizwan, Mary Lee, Gwo-Shu, McGregor, Bradley A, Chang, Steven L, Feldman, Adam S, Wu, Catherine J, McDermott, David F, Heng, Daniel Y C, Signoretti, Sabina, Van Allen, Eliezer M, Choueiri, Toni K, Viswanathan, Srinivas R

Volltext

LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans von Tu, Ho-Chou, Schwitalla, Sarah, Qian, Zhirong, LaPier, Grace S, Yermalovich, Alena, Ku, Yuan-Chieh, Chen, Shann-Ching, Viswanathan, Srinivas R, Zhu, Hao, Nishihara, Reiko, Inamura, Kentaro, Kim, Sun A, Morikawa, Teppei, Mima, Kosuke, Sukawa, Yasutaka, Yang, Juhong, Meredith, Gavin, Fuchs, Charles S, Ogino, Shuji, Daley, George Q

Volltext

Efficacy of Cabozantinib in Metastatic MiT Family Translocation Renal Cell Carcinomas von Thouvenin, Jonathan, Alhalabi, Omar, Carlo, Maria, Carril-Ajuria, Lucia, Hirsch, Laure, Martinez-Chanza, Nieves, Négrier, Sylvie, Campedel, Luca, Martini, Dylan, Borchiellini, Delphine, Chahoud, Jad, Lodi, Massimo, Barthélémy, Philippe, Hasanov, Elshad, Hahn, Andrew W, Gil, Thierry, Viswanathan, Srinivas R, Bakouny, Ziad, Msaouel, Pavlos, Asim Bilen, Mehmet, Choueiri, Toni K, Albiges, Laurence, Tannir, Nizar M, Malouf, Gabriel G

Volltext