Bifunctional small molecules that mediate the degradation of extracellular proteins von Caianiello, David F., Zhang, Mengwen, Ray, Jason D., Howell, Rebecca A., Swartzel, Jake C., Branham, Emily M. J., Chirkin, Egor, Sabbasani, Venkata R., Gong, Angela Z., McDonald, David M., Muthusamy, Viswanathan, Spiegel, David A.

Volltext

Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses von Jiang, Xiaodong, Muthusamy, Viswanathan, Fedorova, Olga, Kong, Yong, Kim, Daniel J, Bosenberg, Marcus, Pyle, Anna Marie, Iwasaki, Akiko

Volltext

Targeting Pyruvate Kinase M2 Phosphorylation Reverses Aggressive Cancer Phenotypes von Apostolidi, Maria, Vathiotis, Ioannis A, Muthusamy, Viswanathan, Gaule, Patricia, Gassaway, Brandon M, Rimm, David L, Rinehart, Jesse

Volltext

DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR von Micevic, Goran, Muthusamy, Viswanathan, Damsky, William, Theodosakis, Nicholas, Liu, Xiaoni, Meeth, Katrina, Wingrove, Emily, Santhanakrishnan, Manjula, Bosenberg, Marcus

Volltext

Re-engineering the Immune Response to Metastatic Cancer: Antibody-Recruiting Small Molecules Targeting the Urokinase Receptor von Rullo, Anthony F., Fitzgerald, Kelly J., Muthusamy, Viswanathan, Liu, Min, Yuan, Cai, Huang, Mingdong, Kim, Minsup, Cho, Art E., Spiegel, David A.

Volltext

mTORC1 Activation Blocks BrafV600E-Induced Growth Arrest but Is Insufficient for Melanoma Formation von Damsky, William, Micevic, Goran, Meeth, Katrina, Muthusamy, Viswanathan, Curley, David P., Santhanakrishnan, Manjula, Erdelyi, Ildiko, Platt, James T., Huang, Laura, Theodosakis, Nicholas, Zaidi, M. Raza, Tighe, Scott, Davies, Michael A., Dankort, David, McMahon, Martin, Merlino, Glenn, Bardeesy, Nabeel, Bosenberg, Marcus

Volltext

Tackling FGFR3-driven bladder cancer with a promising synergistic FGFR/HDAC targeted therapy von Wang, Zechen, Muthusamy, Viswanathan, Petrylak, Daniel P., Anderson, Karen S.

Volltext

Epigenetic silencing of novel tumor suppressors in malignant melanoma von MUTHUSAMY, Viswanathan, DURAISAMY, Sekhar, BRADBURY, C. Matthew, HOBBS, Cara, CURLEY, David P, NELSON, Betsy, BOSENBERG, Marcus

Volltext

Promoter hypermethylation profile of tumor‐associated genes p16, p15, hMLH1, MGMT and E‐cadherin in oral squamous cell carcinoma von Viswanathan, Muthusamy, Tsuchida, Nobuo, Shanmugam, Govindaswamy

Volltext

Phosphoproteomic screen identifies potential therapeutic targets in melanoma von Tworkoski, Kathryn, Singhal, Garima, Szpakowski, Sebastian, Zito, Christina Ivins, Bacchiocchi, Antonella, Muthusamy, Viswanathan, Bosenberg, Marcus, Krauthammer, Michael, Halaban, Ruth, Stern, David F

Volltext

1069 IL-12 mRNA monotherapy is effective in murine tumors resistant to checkpoint inhibition von Santha, Sreevidya, Lakshmipathi, Jayalakshmi, Li, Man, Qian, Yuping, Luheshi, Nadia, Politi, Katerina, Bosenberg, Marcus, Eyles, Jim, Muthusamy, Viswanathan

Volltext

Amplification of CDK4 and MDM2 in malignant melanoma von Muthusamy, Viswanathan, Hobbs, Cara, Nogueira, Cristina, Cordon-Cardo, Carlos, McKee, Phillip H., Chin, Lynda, Bosenberg, Marcus W.

Volltext

Characterization of melanocyte-specific inducible Cre recombinase transgenic mice von Bosenberg, Marcus, Muthusamy, Viswanathan, Curley, David P., Wang, Zhenxiong, Hobbs, Cara, Nelson, Betsy, Nogueira, Cristina, Horner II, James W., DePinho, Ronald, Chin, Lynda

Volltext

Redefining regulation of DNA methylation by RNA interference von Muthusamy, Viswanathan, Bosenberg, Marcus, Wajapeyee, Narendra

Volltext

Familial multiple pilomatrixomas as a presentation of attenuated adenomatosis polyposis coli von Trufant, Joshua, Kurz, Wayne, Frankel, Amylynne, Muthusamy, Viswanathan, McKinnon, Wendy, Greenblatt, Marc, Lazar, Alex, Cook, Deborah, Bosenberg, Marcus

Volltext

The Hematopoietic Stem Cell Regulatory Gene Latexin Has Tumor-Suppressive Properties in Malignant Melanoma von Muthusamy, Viswanathan, Premi, Sanjay, Soper, Cara, Platt, James, Bosenberg, Marcus

Volltext

Abstract P5-17-01: Targeting Acetyl-CoA carboxylase in pre-clinical breast cancer models von Foldi, Julia, Marczyk, Michal, Gunasekharan, Vignesh, Qing, Tao, Sehgal, Raghav, Shan, Naing Lin, Muthusamy, Viswanathan, Umlau, Sheila, Surovtseva, Yulia V., Kibbey, Richard, Pusztai, Lajos

Volltext

Abstract P258: CBX-12 (alphalexTM-exatecan) sensitizes tumors to immune checkpoint blockade in an antigen agnostic manner by immune activation von Gayle, Sophia, Vasquez, Juan, Paradis, Timothy, Jones, Kelli, Sundaram, Ranjini, van Doorn, Jinny, Muthusamy, Viswanathan, Bindra, Ranjit S., Aiello, Robert J., Paralkar, Vishwas

Volltext

Neutralization of Pathogenic Fungi with Small‐Molecule Immunotherapeutics von Chirkin, Egor, Muthusamy, Viswanathan, Mann, Paul, Roemer, Terry, Nantermet, Philippe G., Spiegel, David A.

Volltext

RASGRF1 Fusions Activate Oncogenic RAS Signaling and Confer Sensitivity to MEK Inhibition von Hunihan, Lisa, Zhao, Dejian, Lazowski, Heather, Li, Man, Qian, Yuping, Abriola, Laura, Surovtseva, Yulia V, Muthusamy, Viswanathan, Tanoue, Lynn T, Rothberg, Bonnie E Gould, Schalper, Kurt A, Herbst, Roy S, Wilson, Frederick H

Volltext