Assessment of Interspecies Differences in Drug-Induced QTc Interval Prolongation in Cynomolgus Monkeys, Dogs and Humans von Dubois, V. F. S., de Witte, W. E. A., Visser, S. A. G., Danhof, M., Della Pasqua, O.

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Good Practices in Model‐Informed Drug Discovery and Development: Practice, Application, and Documentation von Marshall, SF, Burghaus, R, Cosson, V, Cheung, SYA, Chenel, M, DellaPasqua, O, Frey, N, Hamrén, B, Harnisch, L, Ivanow, F, Kerbusch, T, Lippert, J, Milligan, PA, Rohou, S, Staab, A, Steimer, JL, Tornøe, C, Visser, SAG

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Implementation of Quantitative and Systems Pharmacology in Large Pharma von Visser, S A G, Alwis, D P, Kerbusch, T, Stone, J A, Allerheiligen, S R B

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Inter‐study variability of preclinical in vivo safety studies and translational exposure–QTc relationships – a PKPD meta‐analysis von Gotta, V, Cools, F, Ammel, K, Gallacher, D J, Visser, S A G, Sannajust, F, Morissette, P, Danhof, M, Graaf, P H

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Modeling and Simulation at the Interface of Nonclinical and Early Clinical Drug Development von Visser, SAG, Manolis, E, Danhof, M, Kerbusch, T

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Pharmaco-electroencephalography and pharmacokinetic-pharmacodynamic modeling in drug development: Focus on preclinical steps von DANHOF, M, VISSER, S. A. G

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Increased brain-predicted aging in treated HIV disease von Cole, James H, Underwood, Jonathan, Caan, Matthan W.A, De Francesco, Davide, van Zoest, Rosan A, Leech, Robert, Wit, Ferdinand W.N.M, Portegies, Peter, Geurtsen, Gert J, Schmand, Ben A, Schim van der Loeff, Maarten F, Franceschi, Claudio, Sabin, Caroline A, Majoie, Charles B.L.M, Winston, Alan, Reiss, Peter, Sharp, David J

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Pain in Guillain-Barré syndrome: A long-term follow-up study von RUTS, L, DRENTHEN, J, JONGEN, J. L. M, HOP, W. C. J, VISSER, G. H, JACOBS, B. C, VAN DOORN, P. A

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Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation von Hall, James P J, Wright, Rosanna C T, Harrison, Ellie, Muddiman, Katie J, Wood, A Jamie, Paterson, Steve, Brockhurst, Michael A

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High-throughput mapping of the phage resistance landscape in E. coli von Mutalik, Vivek K, Adler, Benjamin A, Rishi, Harneet S, Piya, Denish, Zhong, Crystal, Koskella, Britt, Kutter, Elizabeth M, Calendar, Richard, Novichkov, Pavel S, Price, Morgan N, Deutschbauer, Adam M, Arkin, Adam P

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Fetal cerebral blood‐flow redistribution: analysis of Doppler reference charts and association of different thresholds with adverse perinatal outcome von Wolf, H., Stampalija, T., Lees, C. C., Arabin, B., Berger, A., Bergman, E., Bhide, A., Bilardo, C. M., Breeze, A. C., Brodszki, J., Calda, P., Cesari, E., Cetin, I., Derks, J., Ebbing, C., Ferrazzi, E., Frusca, T., Ganzevoort, W., Gordijn, S. J., Gyselaers, W., Hecher, K., Klaritsch, P., Krofta, L., Lindgren, P., Lobmaier, S. M., Marlow, N., Maruotti, G. M., Mecacci, F., Myklestad, K., Napolitano, R., Prefumo, F., Raio, L., Richter, J., Sande, R. K., Thornton, J., Valensise, H., Visser, G. H. A., Wee, L.

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Is middle cerebral artery Doppler related to neonatal and 2-year infant outcome in early fetal growth restriction? von Stampalija, Tamara, MD, Arabin, Birgit, MD, Wolf, Hans, MD, Bilardo, Caterina M., MD, Lees, Christoph, MD

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T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment von Jimenez, Viviana Cobos, Wit, Ferdinand W. N. M., Joerink, Maaike, Maurer, Irma, Harskamp, Agnes M., Schouten, Judith, Prins, Maria, van Leeuwen, Ester M. M., Booiman, Thijs, Deeks, Steven G., Reiss, Peter, Kootstra, Neeltje A.

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Determinants of reduced cognitive performance in HIV-1-infected middle-aged men on combination antiretroviral therapy von Schouten, Judith, Su, Tanja, Wit, Ferdinand W, Kootstra, Neeltje A, Caan, Matthan W.A, Geurtsen, Gert J, Schmand, Ben A, Stolte, Ineke G, Prins, Maria, Majoie, Charles B, Portegies, Peter, Reiss, Peter

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Single-cell copy number variant detection reveals the dynamics and diversity of adaptation von Lauer, Stephanie, Avecilla, Grace, Spealman, Pieter, Sethia, Gunjan, Brandt, Nathan, Levy, Sasha F, Gresham, David

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Hyperglycemia and Adverse Pregnancy Outcomes von Metzger, Boyd E, Lowe, Lynn P, Dyer, Alan R, Trimble, Elisabeth R, Chaovarindr, Udom, Coustan, Donald R, Hadden, David R, McCance, David R, Hod, Moshe, McIntyre, Harold David, Oats, Jeremy J N, Persson, Bengt, Rogers, Michael S, Sacks, David A

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Interplay between the cell envelope and mobile genetic elements shapes gene flow in populations of the nosocomial pathogen Klebsiella pneumoniae von Haudiquet, Matthieu, Buffet, Amandine, Rendueles, Olaya, Rocha, Eduardo P. C

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Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers von van Zoest, Rosan A, Underwood, Jonathan, De Francesco, Davide, Sabin, Caroline A, Cole, James H, Wit, Ferdinand W, Caan, Matthan W A, Kootstra, Neeltje A, Fuchs, Dietmar, Zetterberg, Henrik, Majoie, Charles B L M, Portegies, Peter, Winston, Alan, Sharp, David J, Gisslén, Magnus, Reiss, Peter

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Horizontal gene transfer and ecological interactions jointly control microbiome stability von Coyte, Katharine Z, Stevenson, Cagla, Knight, Christopher G, Harrison, Ellie, Hall, James P J, Brockhurst, Michael A

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HIV infection is independently associated with frailty in middle-aged HIV type 1-infected individuals compared with similar but uninfected controls von Kooij, Katherine W, Wit, Ferdinand W.N.M, Schouten, Judith, van der Valk, Marc, Godfried, Mieke H, Stolte, Ineke G, Prins, Maria, Falutz, Julian, Reiss, Peter

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