Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study von Farley, John, Prof, Brady, William E, PhD, Vathipadiekal, Vinod, PhD, Lankes, Heather A, PhD, Coleman, Robert, Prof, Morgan, Mark A, Prof, Mannel, Robert, Prof, Yamada, S Diane, Prof, Mutch, David, Prof, Rodgers, William H, Prof, Birrer, Michael, MD, Gershenson, David M, MD

Volltext

Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L von LaFargue, Christopher J., Amero, Paola, Noh, Kyunghee, Mangala, Lingegowda S., Wen, Yunfei, Bayraktar, Emine, Umamaheswaran, Sujanitha, Stur, Elaine, Dasari, Santosh K., Ivan, Cristina, Pradeep, Sunila, Yoo, Wonbeak, Lu, Chunhua, Jennings, Nicholas B., Vathipadiekal, Vinod, Hu, Wei, Chelariu-Raicu, Anca, Ku, Zhiqiang, Deng, Hui, Xiong, Wei, Choi, Hyun-Jin, Hu, Min, Kiyama, Takae, Mao, Chai-An, Ali-Fehmi, Rouba, Birrer, Michael J., Liu, Jinsong, Zhang, Ningyan, Lopez-Berestein, Gabriel, de Franciscis, Vittorio, An, Zhiqiang, Sood, Anil K.

Volltext

CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis von Sosulski, Amanda, Horn, Heiko, Zhang, Lihua, Coletti, Caroline, Vathipadiekal, Vinod, Castro, Cesar M, Birrer, Michael J, Nagano, Osamu, Saya, Hideyuki, Lage, Kasper, Donahoe, Patricia K, Pépin, David

Volltext

A Gene Signature Predictive for Outcome in Advanced Ovarian Cancer Identifies a Survival Factor: Microfibril-Associated Glycoprotein 2 von Mok, Samuel C., Bonome, Tomas, Vathipadiekal, Vinod, Bell, Aaron, Johnson, Michael E., Wong, kwong-kwok, Park, Dong-Choon, Hao, Ke, Yip, Daniel K.P., Donninger, Howard, Ozbun, Laurent, Samimi, Goli, Brady, John, Randonovich, Mike, Pise-Masison, Cindy A., Barrett, J. Carl, Wong, Wing H., Welch, William R., Berkowitz, Ross S., Birrer, Michael J.

Volltext

Identification of a potential ovarian cancer stem cell gene expression profile from advanced stage papillary serous ovarian cancer von Vathipadiekal, Vinod, Saxena, Deepa, Mok, Samuel C, Hauschka, Peter V, Ozbun, Laurent, Birrer, Michael J

Volltext

AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer von Pépin, David, Sosulski, Amanda, Zhang, Lihua, Wang, Dan, Vathipadiekal, Vinod, Hendren, Katherine, Coletti, Caroline M., Yu, Aaron, Castro, Cesar M., Birrer, Michael J., Gao, Guangping, Donahoe, Patricia K.

Volltext

Human H-ficolin inhibits replication of seasonal and pandemic influenza A viruses von Verma, Anamika, White, Mitchell, Vathipadiekal, Vinod, Tripathi, Shweta, Mbianda, Julvet, Ieong, Micheal, Qi, Li, Taubenberger, Jeffery K, Takahashi, Kazue, Jensenius, Jens C, Thiel, Steffen, Hartshorn, Kevan L

Volltext

An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer von Sethi, Geetika, Pathak, Harsh B, Zhang, Hong, Zhou, Yan, Einarson, Margret B, Vathipadiekal, Vinod, Gunewardena, Sumedha, Birrer, Michael J, Godwin, Andrew K

Volltext

Identification of novel therapeutic targets in microdissected clear cell ovarian cancers von Stany, Michael P, Vathipadiekal, Vinod, Ozbun, Laurent, Stone, Rebecca L, Mok, Samuel C, Xue, Hui, Kagami, Takashi, Wang, Yuwei, McAlpine, Jessica N, Bowtell, David, Gout, Peter W, Miller, Dianne M, Gilks, C Blake, Huntsman, David G, Ellard, Susan L, Wang, Yu-Zhuo, Vivas-Mejia, Pablo, Lopez-Berestein, Gabriel, Sood, Anil K, Birrer, Michael J

Volltext

Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array von Vathipadiekal, Vinod, Wang, Victoria, Wei, Wei, Waldron, Levi, Drapkin, Ronny, Gillette, Michael, Skates, Steven, Birrer, Michael

Volltext

Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model von McCann, Christopher K, Growdon, Whitfield B, Kulkarni-Datar, Kashmira, Curley, Michael D, Friel, Anne M, Proctor, Jennifer L, Sheikh, Hana, Deyneko, Igor, Ferguson, Jeanne A, Vathipadiekal, Vinod, Birrer, Michael J, Borger, Darrell R, Mohapatra, Gayatry, Zukerberg, Lawrence R, Foster, Rosemary, Macdougall, John R, Rueda, Bo R

Volltext

SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK von Li, Hua, Cai, Qi, Wu, Hong, Vathipadiekal, Vinod, Dobbin, Zachary C, Li, Tianyu, Hua, Xiang, Landen, Charles N, Birrer, Michael J, Sánchez-Beato, Margarita, Zhang, Rugang

Volltext

Abstract 3013: Elucidating the functional role of microfibril-associated glycoprotein-2 (MAGP-2) in human ovarian cancer von Vathipadiekal, Vinod, Wei, Wei, Kwok, Tim, Birrer, Michael

Volltext

Stereochemistry Enhances Potency, Efficacy, and Durability of Malat1 Antisense Oligonucleotides In Vitro and In Vivo in Multiple Species von Byrne, Michael, Vathipadiekal, Vinod, Apponi, Luciano, Iwamoto, Naoki, Kandasamy, Pachamuthu, Longo, Kenneth, Liu, Fangjun, Looby, Richard, Norwood, Lauren, Shah, Anee, Shelke, Juili Dilip, Shivalila, Chikdu, Yang, Hailin, Yin, Yuan, Guo, Lankai, Bowman, Keith, Vargeese, Chandra

Volltext

Abstract B26: Cell surface expression of CD44v8-10 is associated with good prognosis while cleaved extracellular domain is a marker of poor prognosis in high-grade serous epithelia... von Pepin, David, Sosulski, Amanda, Horn, Heiko, Zhang, Lihua, Coletti, Caroline, Vathipadiekal, vinod, Castro, Cesar M., Birrer, Michael J., Nagano, Osamu, Saya, Hidekuyi, Lage, Kasper, Donahoe, Patricia K.

Volltext

CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis von Sosulski, Amanda, Horn, Heiko, Zhang, Lihua, Coletti, Caroline, Vathipadiekal, Vinod, Castro, Cesar M, Birrer, Michael J, Nagano, Osamu, Saya, Hideyuki, Lage, Kasper, Donahoe, Patricia K, Pépin, David

Volltext

Slow-Tight Binding Inhibition of Xylanase by an Aspartic Protease Inhibitor von Dash, Chandravanu, Vathipadiekal, Vinod, George, Sudeep P., Rao, Mala

Volltext

Abstract 1534: Identification of LMX1B as a novel oncogene in human ovarian cancer von Mohapatra, Gayatry, He, Lei, Guo, Lankai, Vathipadiekal, Vinod, Sergent, Petra, Growdon, Whitfield, Rueda, Bo, Engler, David, Orsulic, Sandra, Birrer, Michael

Volltext

Low-grade and high-grade serous Mullerian carcinoma: Review and analysis of publicly available gene expression profiles von May, Taymaa, Shoni, Melina, Crum, Christopher P, Xian, Wa, Vathipadiekal, Vinod, Birrer, Michael, Rosen, Barry, Tone, Alicia, Murphy, K. Joan

Volltext

Abstract 3001: Aberrantly up-regulated synaptotagmin-like 2 (SYTL2) promotes tumorigenesis of ovarian cancer cells von Kim, Sung-hoon, Mok, Samuel C., Wei, Wei, Vinod, Vathipadiekal, Mohapatra, Gayatry, Birrer, Michael

Volltext