Crystal structure of dihydrofolate reductase from the emerging pathogenic fungus Candida auris von Kirkman, Tim, Sketcher, Alice, de Morais Barroso, Vinicius, Ishida, Kelly, Tosin, Manuela, Dias, Marcio Vinicius Bertacine

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How to Find a Fragment: Methods for Screening and Validation in Fragment‐Based Drug Discovery von Kirkman, Tim, Santos Silva, Catharina, Tosin, Manuela, Bertacine Dias, Marcio Vinicius

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Crystal Structure of GenD2, an NAD-Dependent Oxidoreductase Involved in the Biosynthesis of Gentamicin von de Araújo, Natalia Cerrone, Bury, Priscila dos Santos, Tavares, Maurício Temotheo, Huang, Fanglu, Parise-Filho, Roberto, Leadlay, Peter, Dias, Marcio Vinicius Bertacine

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Structural Basis of the Selectivity of GenN, an Aminoglycoside N‑Methyltransferase Involved in Gentamicin Biosynthesis von Bury, Priscila dos Santos, Huang, Fanglu, Li, Sicong, Sun, Yuhui, Leadlay, Peter F, Dias, Marcio Vinicius Bertacine

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Crystal structures of the closed form of Mycobacterium tuberculosis dihydrofolate reductase in complex with dihydrofolate and antifolates von Ribeiro, João Augusto, Chavez-Pacheco, Sair Maximo, de Oliveira, Gabriel Stephani, Silva, Catharina dos Santos, Giudice, João Henrique Pimenta, Libreros-Zúñiga, Gerardo Andres, Dias, Marcio Vinicius Bertacine

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Mycobacterium tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and a Possible Low Affinity Mechanism to Antifolate Drugs von Dias, Marcio Vinicius Bertacine, Tyrakis, Petros, Domingues, Romenia Ramos, Leme, Adriana Franco Paes, Blundell, Tom L.

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Mutations and insights into the molecular mechanisms of resistance of Mycobacterium tuberculosis to first-line von Rossini, Nicolas de Oliveira, Dias, Marcio Vinicius Bertacine

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Integration of biophysical and biological approaches to validate fragment-like compounds targeting l,d-transpeptidases from Mycobacterium tuberculosis von Andrés Libreros-Zúñiga, Gerardo, Pavão E Pavão, Danilo, de Morais Barroso, Vinicius, Cristina de Moraes Roso Mesquita, Nathalya, Fehelberg Pinto Braga, Saulo, Oliva, Glaucius, Salgado Ferreira, Rafaela, Ishida, Kelly, Vinicius Bertacine Dias, Marcio

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Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors von Kronenberger, Thales, Ferreira, Glaucio Monteiro, de Souza, Alfredo Danilo Ferreira, da Silva Santos, Soraya, Poso, Antti, Ribeiro, João Augusto, Tavares, Maurício Temotheo, Pavan, Fernando Rogério, Trossini, Gustavo Henrique Goulart, Dias, Marcio Vinícius Bertacine, Parise-Filho, Roberto

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Mycobacterium tuberculosis Dihydrofolate Reductase Inhibitors: State of Art Past 20 Years

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An epoxide hydrolase from endophytic Streptomyces shows unique structural features and wide biocatalytic activity von Tormet-González, Gabriela D., Wilson, Carolina, de Oliveira, Gabriel Stephani, dos Santos, Jademilson Celestino, de Oliveira, Luciana G., Dias, Marcio Vinicius Bertacine

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Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir von dos Santos, Denis Marangoni, Canduri, Fernanda, Pereira, José Henrique, Vinicius Bertacine Dias, Márcio, Silva, Rafael Guimarães, Mendes, Maria Anita, Palma, Mário Sérgio, Basso, Luiz Augusto, de Azevedo, Walter Filgueira, Santos, Diógenes Santiago

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Structural basis for inhibition of human PNP by immucillin-H von Filgueira de Azevedo, Walter, Canduri, Fernanda, Marangoni dos Santos, Denis, Henrique Pereira, José, Vinicius Bertacine Dias, Márcio, Guimarães Silva, Rafael, Anita Mendes, Maria, Augusto Basso, Luiz, Sérgio Palma, Mário, Santiago Santos, Diógenes

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Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase von da Silva, Marco Túlio Alves, Silva, Ivan Rosa E, Faim, Lívia Maria, Bellini, Natália Karla, Pereira, Murilo Leão, Lima, Ana Laura, de Jesus, Teresa Cristina Leandro, Costa, Fernanda Cristina, Watanabe, Tatiana Faria, Pereira, Humberto D'Muniz, Valentini, Sandro Roberto, Zanelli, Cleslei Fernando, Borges, Júlio Cesar, Dias, Marcio Vinicius Bertacine, da Cunha, Júlia Pinheiro Chagas, Mittra, Bidyottam, Andrews, Norma W, Thiemann, Otavio Henrique

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Crystal structure of human PNP complexed with guanine von de Azevedo, Walter Filgueira, Canduri, Fernanda, dos Santos, Denis Marangoni, Pereira, José Henrique, Bertacine Dias, Márcio Vinicius, Silva, Rafael Guimarães, Mendes, Maria Anita, Basso, Luiz Augusto, Palma, Mário Sérgio, Santos, Diógenes Santiago

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Structural Basis for the Interaction and Processing of β‑Lactam Antibiotics by l,d‑Transpeptidase 3 (LdtMt3) from Mycobacterium tuberculosis von Libreros-Zúñiga, Gerardo Andrés, dos Santos Silva, Catharina, Salgado Ferreira, Rafaela, Dias, Marcio Vinicius Bertacine

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The crystal structure of Mycobacterium thermoresistibile MurE ligase reveals the binding mode of the substrate m-diaminopimelate von Rossini, Nicolas de Oliveira, Silva, Catharina, Dias, Marcio Vinicius Bertacine

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Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2- trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis von Dias, Marcio Vinicius Bertacine, Vasconcelos, Igor Bordin, Prado, Adriane Michele Xavier, Fadel, Valmir, Basso, Luiz Augusto, de Azevedo, Walter Filgueira, Santos, Diógenes Santiago

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Mutations and insights into the molecular mechanisms of resistance of Mycobacterium tuberculosis to first-line drugs von Rossini, Nicolas de Oliveira, Dias, Marcio Vinicius Bertacine

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Molecular models of tryptophan synthase from mycobacterium tuberculosis complexed with inhibitors von Dias, Marcio Vinicius Bertacine, Canduri, Fernanda, da Silveira, Nelson José Freitas, Czekster, Clarissa Melo, Basso, Luis Augusto, Palma, Mário Sérgio, Santos, Diógenes Santiago, de Azevedo, Jr, Walter Filgueira

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