Visual analysis of gait as a cue to identity von Stevenage, Sarah V., Nixon, Mark S., Vince, Kate

Volltext

Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation von Vince, James E., Wong, W. Wei-Lynn, Gentle, Ian, Lawlor, Kate E., Allam, Ramanjaneyulu, O'Reilly, Lorraine, Mason, Kylie, Gross, Olaf, Ma, Stephen, Guarda, Greta, Anderton, Holly, Castillo, Rosa, Häcker, Georg, Silke, John, Tschopp, Jürg

Volltext

XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation von Lawlor, Kate E., Feltham, Rebecca, Yabal, Monica, Conos, Stephanie A., Chen, Kaiwen W., Ziehe, Stephanie, Graß, Carina, Zhan, Yifan, Nguyen, Tan A., Hall, Cathrine, Vince, Angelina J., Chatfield, Simon M., D’Silva, Damian B., Pang, Kenneth C., Schroder, Kate, Silke, John, Vaux, David L., Jost, Philipp J., Vince, James E.

Volltext

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner von Conos, Stephanie A., Chen, Kaiwen W., De Nardo, Dominic, Hara, Hideki, Whitehead, Lachlan, Núñez, Gabriel, Masters, Seth L., Murphy, James M., Schroder, Kate, Vaux, David L., Lawlor, Kate E., Lindqvist, Lisa M., Vince, James E.

Volltext

The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation von Vijayaraj, Swarna L., Feltham, Rebecca, Rashidi, Maryam, Frank, Daniel, Liu, Zhengyang, Simpson, Daniel S., Ebert, Gregor, Vince, Angelina, Herold, Marco J., Kueh, Andrew, Pearson, Jaclyn S., Dagley, Laura F., Murphy, James M., Webb, Andrew I., Lawlor, Kate E., Vince, James E.

Volltext

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation von Vince, James E., De Nardo, Dominic, Gao, Wenqing, Vince, Angelina J., Hall, Cathrine, McArthur, Kate, Simpson, Daniel, Vijayaraj, Swarna, Lindqvist, Lisa M., Bouillet, Philippe, Rizzacasa, Mark A., Man, Si Ming, Silke, John, Masters, Seth L., Lessene, Guillaume, Huang, David C.S., Gray, Daniel H.D., Kile, Benjamin T., Shao, Feng, Lawlor, Kate E.

Volltext

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL von Lawlor, Kate E., Khan, Nufail, Mildenhall, Alison, Gerlic, Motti, Croker, Ben A., D’Cruz, Akshay A., Hall, Cathrine, Kaur Spall, Sukhdeep, Anderton, Holly, Masters, Seth L., Rashidi, Maryam, Wicks, Ian P., Alexander, Warren S., Mitsuuchi, Yasuhiro, Benetatos, Christopher A., Condon, Stephen M., Wong, W. Wei-Lynn, Silke, John, Vaux, David L., Vince, James E.

Volltext

Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model von Erlich, Ziv, Shlomovitz, Inbar, Edry-Botzer, Liat, Cohen, Hadar, Frank, Daniel, Wang, Hanqing, Lew, Andrew M., Lawlor, Kate E., Zhan, Yifan, Vince, James E., Gerlic, Motti

Volltext

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis von Rickard, James A., O’Donnell, Joanne A., Evans, Joseph M., Lalaoui, Najoua, Poh, Ashleigh R., Rogers, TeWhiti, Vince, James E., Lawlor, Kate E., Ninnis, Robert L., Anderton, Holly, Hall, Cathrine, Spall, Sukhdeep K., Phesse, Toby J., Abud, Helen E., Cengia, Louise H., Corbin, Jason, Mifsud, Sandra, Di Rago, Ladina, Metcalf, Donald, Ernst, Matthias, Dewson, Grant, Roberts, Andrew W., Alexander, Warren S., Murphy, James M., Ekert, Paul G., Masters, Seth L., Vaux, David L., Croker, Ben A., Gerlic, Motti, Silke, John

Volltext

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma von Best, Sarah A., Ding, Sheryl, Kersbergen, Ariena, Dong, Xueyi, Song, Ji-Ying, Xie, Yi, Reljic, Boris, Li, Kaiming, Vince, James E., Rathi, Vivek, Wright, Gavin M., Ritchie, Matthew E., Sutherland, Kate D.

Volltext

Gasdermin and MLKL necrotic cell death effectors: Signaling and diseases von Lawlor, Kate E., Murphy, James M., Vince, James E.

Volltext

Ambiguities in NLRP3 inflammasome regulation: Is there a role for mitochondria? von Lawlor, Kate E., Vince, James E.

Volltext

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner von Wong, W. Wei-Lynn, Vince, James E., Lalaoui, Najoua, Lawlor, Kate E., Chau, Diep, Bankovacki, Aleksandra, Anderton, Holly, Metcalf, Donald, O'Reilly, Lorraine, Jost, Philipp J., Murphy, James M., Alexander, Warren S., Strasser, Andreas, Vaux, David L., Silke, John

Volltext

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming von Allam, Ramanjaneyulu, Lawlor, Kate E, Yu, Eric Chi-Wang, Mildenhall, Alison L, Moujalled, Donia M, Lewis, Rowena S, Ke, Francine, Mason, Kylie D, White, Michael J, Stacey, Katryn J, Strasser, Andreas, O'Reilly, Lorraine A, Alexander, Warren, Kile, Benjamin T, Vaux, David L, Vince, James E

Volltext

More to life than death: molecular determinants of necroptotic and non-necroptotic RIP3 kinase signaling von Khan, Nufail, Lawlor, Kate E, Murphy, James M, Vince, James E

Volltext

Caspase‐8: not so silently deadly von Feltham, Rebecca, Vince, James E, Lawlor, Kate E

Volltext

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway von Simpson, Daniel S., Pang, Jiyi, Weir, Ashley, Kong, Isabella Y., Fritsch, Melanie, Rashidi, Maryam, Cooney, James P., Davidson, Kathryn C., Speir, Mary, Djajawi, Tirta M., Hughes, Sebastian, Mackiewicz, Liana, Dayton, Merle, Anderton, Holly, Doerflinger, Marcel, Deng, Yexuan, Huang, Allan Shuai, Conos, Stephanie A., Tye, Hazel, Chow, Seong H., Rahman, Arfatur, Norton, Raymond S., Naderer, Thomas, Nicholson, Sandra E., Burgio, Gaetan, Man, Si Ming, Groom, Joanna R., Herold, Marco J., Hawkins, Edwin D., Lawlor, Kate E., Strasser, Andreas, Silke, John, Pellegrini, Marc, Kashkar, Hamid, Feltham, Rebecca, Vince, James E.

Volltext

The evolution and social determinants of mental health during the first wave of the COVID-19 outbreak in Luxembourg von Ribeiro, Fabiana, Schröder, Valerie E., Krüger, Rejko, Leist, Anja K.

Volltext

RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation von Tran, Hong Tri, Kratina, Tobias, Coutansais, Auriane, Michalek, Dominika, Hogan, Benjamin M., Lawlor, Kate E., Vince, James E., Silke, John, Lalaoui, Najoua

Volltext

Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation von Deo, Pankaj, Chow, Seong H., Han, Mei-Ling, Speir, Mary, Huang, Cheng, Schittenhelm, Ralf B., Dhital, Subhash, Emery, Jack, Li, Jian, Kile, Benjamin T., Vince, James E., Lawlor, Kate E., Naderer, Thomas

Volltext