The NLRP3 inflammasome in health and disease: the good, the bad and the ugly von Menu, P., Vince, J. E.

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Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation von Vince, James E., Wong, W. Wei-Lynn, Gentle, Ian, Lawlor, Kate E., Allam, Ramanjaneyulu, O'Reilly, Lorraine, Mason, Kylie, Gross, Olaf, Ma, Stephen, Guarda, Greta, Anderton, Holly, Castillo, Rosa, Häcker, Georg, Silke, John, Tschopp, Jürg

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The intersection of cell death and inflammasome activation von Vince, James E., Silke, John

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Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner von Conos, Stephanie A., Chen, Kaiwen W., De Nardo, Dominic, Hara, Hideki, Whitehead, Lachlan, Núñez, Gabriel, Masters, Seth L., Murphy, James M., Schroder, Kate, Vaux, David L., Lawlor, Kate E., Lindqvist, Lisa M., Vince, James E.

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The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation von Vijayaraj, Swarna L., Feltham, Rebecca, Rashidi, Maryam, Frank, Daniel, Liu, Zhengyang, Simpson, Daniel S., Ebert, Gregor, Vince, Angelina, Herold, Marco J., Kueh, Andrew, Pearson, Jaclyn S., Dagley, Laura F., Murphy, James M., Webb, Andrew I., Lawlor, Kate E., Vince, James E.

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Pyroptosis versus necroptosis: similarities, differences, and crosstalk von Frank, Daniel, Vince, James E.

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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL von Lawlor, Kate E., Khan, Nufail, Mildenhall, Alison, Gerlic, Motti, Croker, Ben A., D’Cruz, Akshay A., Hall, Cathrine, Kaur Spall, Sukhdeep, Anderton, Holly, Masters, Seth L., Rashidi, Maryam, Wicks, Ian P., Alexander, Warren S., Mitsuuchi, Yasuhiro, Benetatos, Christopher A., Condon, Stephen M., Wong, W. Wei-Lynn, Silke, John, Vaux, David L., Vince, James E.

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Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8 von Sagulenko, Vitaliya, Vitak, Nazarii, Vajjhala, Parimala R., Vince, James E., Stacey, Katryn J.

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XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation von Lawlor, Kate E., Feltham, Rebecca, Yabal, Monica, Conos, Stephanie A., Chen, Kaiwen W., Ziehe, Stephanie, Graß, Carina, Zhan, Yifan, Nguyen, Tan A., Hall, Cathrine, Vince, Angelina J., Chatfield, Simon M., D’Silva, Damian B., Pang, Kenneth C., Schroder, Kate, Silke, John, Vaux, David L., Jost, Philipp J., Vince, James E.

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Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model von Erlich, Ziv, Shlomovitz, Inbar, Edry-Botzer, Liat, Cohen, Hadar, Frank, Daniel, Wang, Hanqing, Lew, Andrew M., Lawlor, Kate E., Zhan, Yifan, Vince, James E., Gerlic, Motti

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Activated MLKL attenuates autophagy following its translocation to intracellular membranes von Frank, Daniel, Vaux, David L., Murphy, James M., Vince, James E., Lindqvist, Lisa M.

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The unexpected role of bioaerosols in the Oxidative Potential of PM von Samake, A., Uzu, G., Martins, J. M. F., Calas, A., Vince, E., Parat, S., Jaffrezo, J. L.

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AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC von Sagulenko, V, Thygesen, S J, Sester, D P, Idris, A, Cridland, J A, Vajjhala, P R, Roberts, T L, Schroder, K, Vince, J E, Hill, J M, Silke, J, Stacey, K J

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Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications von Sharma, Arpeeta, Tate, Mitchel, Mathew, Geetha, Vince, James E, Ritchie, Rebecca H, de Haan, Judy B

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RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis von Rickard, James A., O’Donnell, Joanne A., Evans, Joseph M., Lalaoui, Najoua, Poh, Ashleigh R., Rogers, TeWhiti, Vince, James E., Lawlor, Kate E., Ninnis, Robert L., Anderton, Holly, Hall, Cathrine, Spall, Sukhdeep K., Phesse, Toby J., Abud, Helen E., Cengia, Louise H., Corbin, Jason, Mifsud, Sandra, Di Rago, Ladina, Metcalf, Donald, Ernst, Matthias, Dewson, Grant, Roberts, Andrew W., Alexander, Warren S., Murphy, James M., Ekert, Paul G., Masters, Seth L., Vaux, David L., Croker, Ben A., Gerlic, Motti, Silke, John

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Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma von Best, Sarah A., Ding, Sheryl, Kersbergen, Ariena, Dong, Xueyi, Song, Ji-Ying, Xie, Yi, Reljic, Boris, Li, Kaiming, Vince, James E., Rathi, Vivek, Wright, Gavin M., Ritchie, Matthew E., Sutherland, Kate D.

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The factor structure and validity of a diagnostic interview for avoidant/restrictive food intake disorder in a sample of children, adolescents, and young adults von Cooper‐Vince, Christine E., Nwaka, Chika, Eddy, Kamryn T., Misra, Madhusmita, Hadaway, Natalia A., Becker, Kendra R., Lawson, Elizabeth A., Cooke, Lucy, Bryant‐Waugh, Rachel, Thomas, Jennifer J., Micali, Nadia

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Evolutionary divergence of the necroptosis effector MLKL von Tanzer, M C, Matti, I, Hildebrand, J M, Young, S N, Wardak, A, Tripaydonis, A, Petrie, E J, Mildenhall, A L, Vaux, D L, Vince, J E, Czabotar, P E, Silke, J, Murphy, J M

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cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner von Wong, W. Wei-Lynn, Vince, James E., Lalaoui, Najoua, Lawlor, Kate E., Chau, Diep, Bankovacki, Aleksandra, Anderton, Holly, Metcalf, Donald, O'Reilly, Lorraine, Jost, Philipp J., Murphy, James M., Alexander, Warren S., Strasser, Andreas, Vaux, David L., Silke, John

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Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming von Allam, Ramanjaneyulu, Lawlor, Kate E, Yu, Eric Chi-Wang, Mildenhall, Alison L, Moujalled, Donia M, Lewis, Rowena S, Ke, Francine, Mason, Kylie D, White, Michael J, Stacey, Katryn J, Strasser, Andreas, O'Reilly, Lorraine A, Alexander, Warren, Kile, Benjamin T, Vaux, David L, Vince, James E

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