Noxa: at the tip of the balance between life and death von Ploner, C, Kofler, R, Villunger, A

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miR-326 targets antiapoptotic Bcl-xL and mediates apoptosis in human platelets von Yu, Shifang, Huang, Huicong, Deng, Gang, Xie, Zuoting, Ye, Yincai, Guo, Ruide, Cai, Xuejiao, Hong, Junying, Qian, Dingliang, Zhou, Xiangjing, Tao, Zhihua, Chen, Bile, Li, Qiang

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The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization von Stamelos, Vasileios A, Fisher, Natalie, Bamrah, Harnoor, Voisey, Carolyn, Price, Joshua C, Farrell, William E, Redman, Charles W, Richardson, Alan

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Contrasting quiescent G0 phase with mitotic cell cycling in the mouse immune system von Tomura, Michio, Sakaue-Sawano, Asako, Mori, Yoshiko, Takase-Utsugi, Mitsuyo, Hata, Akihiro, Ohtawa, Kenji, Kanagawa, Osami, Miyawaki, Atsushi

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Bacterial fucose-rich polysaccharide stabilizes MAPK-mediated Nrf2/Keap1 signaling by directly scavenging reactive oxygen species during hydrogen peroxide-induced apoptosis of huma... von Roy Chowdhury, Sougata, Sengupta, Suman, Biswas, Subir, Sinha, Tridib Kumar, Sen, Ramkrishna, Basak, Ratan Kumar, Adhikari, Basudam, Bhattacharyya, Arindam

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Leptin is an anti-apoptotic effector in placental cells involving p53 downregulation von Toro, Ayelén Rayen, Maymó, Julieta Lorena, Ibarbalz, Federico Matías, Pérez-Pérez, Antonio, Maskin, Bernardo, Faletti, Alicia Graciela, Sánchez-Margalet, Víctor, Varone, Cecilia Laura

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Apoptosis and pro-inflammatory cytokine response of mast cells induced by influenza A viruses von Liu, Bo, Meng, Di, Wei, Tangting, Zhang, Siyi, Hu, Yanxin, Wang, Ming

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PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors von Farrés, J, Llacuna, L, Martin-Caballero, J, Martínez, C, Lozano, J J, Ampurdanés, C, López-Contreras, A J, Florensa, L, Navarro, J, Ottina, E, Dantzer, F, Schreiber, V, Villunger, A, Fernández-Capetillo, O, Yélamos, J

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Combining paclitaxel with ABT-263 has a synergistic effect on paclitaxel resistant prostate cancer cells von Wang, Chihuei, Huang, Shih-Bo, Yang, Min-Chi, Lin, Yi-Tsen, Chu, I-Hung, Shen, Ya-Ni, Chiu, Yueh-Ho, Hung, Shao-Hung, Kang, Lin, Hong, Yi-Ren, Chen, Chung-Hwan

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Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy? von Labi, V, Grespi, F, Baumgartner, F, Villunger, A

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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 von Galluzzi, L, Bravo-San Pedro, J M, Vitale, I, Aaronson, S A, Abrams, J M, Adam, D, Alnemri, E S, Andrews, D, Baehrecke, E H, Bazan, N G, Bertrand, M J, Blagosklonny, M V, Blomgren, K, Borner, C, Bredesen, D E, Brenner, C, Campanella, M, Candi, E, Cecconi, F, Chan, F K, Chandel, N S, Cheng, E H, Chipuk, J E, Cidlowski, J A, Ciechanover, A, Dawson, V L, De Laurenzi, V, De Maria, R, Debatin, K-M, Di Daniele, N, Dixit, V M, Dynlacht, B D, El-Deiry, W S, Fimia, G M, Flavell, R A, Garrido, C, Green, D R, Gronemeyer, H, Hajnoczky, G, Hardwick, J M, Hengartner, M O, Ichijo, H, Joseph, B, Jost, P J, Kaufmann, T, Kepp, O, Klionsky, D J, Knight, R A, Kumar, S, Lemasters, J J, Levine, B, Linkermann, A, Lipton, S A, Lockshin, R A, López-Otín, C, Lugli, E, Madeo, F, Malorni, W, Marine, J-C, Martin, S J, Martinou, J-C, Medema, J P, Meier, P, Melino, S, Mizushima, N, Moll, U, Muñoz-Pinedo, C, Nuñez, G, Oberst, A, Panaretakis, T, Penninger, J M, Peter, M E, Piacentini, M, Pinton, P, Prehn, J H, Puthalakath, H, Rabinovich, G A, Ravichandran, K S, Rizzuto, R, Rodrigues, C M, Rubinsztein, D C, Rudel, T, Stockwell, B R, Szabadkai, G, Tait, S W, Tang, H L, Tavernarakis, N, Tsujimoto, Y, Vanden Berghe, T, Vandenabeele, P, Villunger, A, Wagner, E F, Walczak, H, White, E, Wood, W G, Yuan, J, Zakeri, Z, Zhivotovsky, B, Melino, G, Kroemer, G

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Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhan... von Kurosu, Tetsuya, Nagao, Toshikage, Wu, Nan, Oshikawa, Gaku, Miura, Osamu

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Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release von Ishii, Yuki, Nhiayi, May Keu, Tse, Edison, Cheng, Jonathan, Massimino, Michele, Durden, Donald L, Vigneri, Paolo, Wang, Jean Y J

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Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts von Sharma, Ramaswamy, Callaway, Danielle, Vanegas, Difernando, Bendele, Michelle, Lopez-Cruzan, Marisa, Horn, Diane, Guda, Teja, Fajardo, Roberto, Abboud-Werner, Sherry, Herman, Brian

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How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? von Olsson, A, Manzl, C, Strasser, A, Villunger, A

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OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis von Wroblewski, David, Jiang, Chen Chen, Croft, Amanda, Farrelly, Margaret L, Zhang, Xu Dong, Hersey, Peter

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BH3-only proteins in cell death initiation, malignant disease and anticancer therapy von Labi, V, Erlacher, M, Kiessling, S, Villunger, A

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PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines von Yanagi, Teruki, Shi, Ranxin, Aza-Blanc, Pedro, Reed, John C, Matsuzawa, Shu-ichi

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Interleukin-1β enhances FasL-induced caspase-3/-7 activity without increasing apoptosis in primary mouse hepatocytes von Lutz, Anna, Sanwald, Julia, Thomas, Maria, Feuer, Ronny, Sawodny, Oliver, Ederer, Michael, Borner, Christoph, Humar, Matjaz, Merfort, Irmgard

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BEX1 promotes imatinib-induced apoptosis by binding to and antagonizing BCL-2 von Xiao, Qian, Hu, Yeting, Liu, Yue, Wang, Zhanhuai, Geng, Haitao, Hu, Lifeng, Xu, Dengyong, Wang, Ke, Zheng, Lei, Zheng, Shu, Ding, Kefeng

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