A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer von Berns, Katrien, Horlings, Hugo M., Hennessy, Bryan T., Madiredjo, Mandy, Hijmans, E. Marielle, Beelen, Karin, Linn, Sabine C., Gonzalez-Angulo, Ana Maria, Stemke-Hale, Katherine, Hauptmann, Michael, Beijersbergen, Roderick L., Mills, Gordon B., van de Vijver, Marc J., Bernards, René

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interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer von Weichselbaum, Ralph R, Ishwaran, Hemant, Yoon, Taewon, Nuyten, Dimitry S.A, Baker, Samuel W, Khodarev, Nikolai, Su, Andy W, Shaikh, Arif Y, Roach, Paul, Kreike, Bas, Roizman, Bernard, Bergh, Jonas, Pawitan, Yudi, van de Vijver, Marc J, Minn, Andy J

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Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract von Damhofer, Helene, Ebbing, Eva A, Steins, Anne, Welling, Lieke, Tol, Johanna A, Krishnadath, Kausilia K, van Leusden, Tom, van de Vijver, Marc J, Besselink, Marc G, Busch, Olivier R, Henegouwen, Mark I van Berge, van Delden, Otto, Meijer, Sybren L, Dijk, Frederike, Medema, Jan Paul, van Laarhoven, Hanneke W, Bijlsma, Maarten F

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Continuing Risk of Ipsilateral Breast Relapse After Breast-Conserving Therapy at Long-Term Follow-up von Kreike, Bas, M.D, Hart, Augustinus A.M., M.Sc, van de Velde, Tony, B.Sc, Borger, Jacques, M.D., Ph.D, Peterse, Hans, M.D, Rutgers, Emiel, M.D., Ph.D, Bartelink, Harry, M.D., Ph.D, van de Vijver, Marc J., M.D., Ph.D

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Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients von de Sousa E Melo, Felipe, Colak, Selcuk, Buikhuisen, Joyce, Koster, Jan, Cameron, Kate, de Jong, Joan H., Tuynman, Jurriaan B., Prasetyanti, Pramudita R., Fessler, Evelyn, van den Bergh, Saskia P., Rodermond, Hans, Dekker, Evelien, van der Loos, Chris M., Pals, Steven T., van de Vijver, Marc J., Versteeg, Rogier, Richel, Dick J., Vermeulen, Louis, Medema, Jan Paul

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EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer von Pietersen, Alexandra M, Horlings, Hugo M, Hauptmann, Michael, Langerød, Anita, Ajouaou, Abderrahim, Cornelissen-Steijger, Paulien, Wessels, Lodewijk F, Jonkers, Jos, van de Vijver, Marc J, van Lohuizen, Maarten

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A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer von Reyal, Fabien, van Vliet, Martin H, Armstrong, Nicola J, Horlings, Hugo M, de Visser, Karin E, Kok, Marlen, Teschendorff, Andrew E, Mook, Stella, van 't Veer, Laura, Caldas, Carlos, Salmon, Remy J, van de Vijver, Marc J, Wessels, Lodewyk F A

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Downgrading of Breast Masses Suspicious for Cancer by Using Optoacoustic Breast Imaging von Menezes, Gisela L G, Pijnappel, Ruud M, Meeuwis, Carla, Bisschops, Robertus, Veltman, Jeroen, Lavin, Philip T, van de Vijver, Marc J, Mann, Ritse M

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Participation and yield of colonoscopy versus non-cathartic CT colonography in population-based screening for colorectal cancer: a randomised controlled trial von Stoop, Esther M, MD, de Haan, Margriet C, MD, de Wijkerslooth, Thomas R, MD, Bossuyt, Patrick M, Prof, van Ballegooijen, Marjolein, MD, Nio, C Yung, MD, van de Vijver, Marc J, Prof, Biermann, Katharina, MD, Thomeer, Maarten, MD, van Leerdam, Monique E, MD, Fockens, Paul, Prof, Stoker, Jaap, Prof, Kuipers, Ernst J, Prof, Dekker, Evelien, Dr

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Predictive Factors for Local Recurrence in Breast Cancer von van der Leij, Femke, MD, Elkhuizen, Paula H.M., MD, PhD, Bartelink, Harry, MD, PhD, van de Vijver, Marc J., MD, PhD

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Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival von Sobral-Leite, Marcelo, Van de Vijver, Koen, Michaut, Magali, van der Linden, Rianne, Hooijer, Gerrit K.J., Horlings, Hugo M., Severson, Tesa M., Mulligan, Anna Marie, Weerasooriya, Nayana, Sanders, Joyce, Glas, Annuska M, Wehkamp, Diederik, Mittempergher, Lorenza, Kersten, Kelly, Cimino-Mathews, Ashley, Peters, Dennis, Hooijberg, Erik, Broeks, Annegien, van de Vijver, Marc J., Bernards, Rene, Andrulis, Irene L., Kok, Marleen, de Visser, Karin E., Schmidt, Marjanka K.

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Papillary and neuroendocrine breast lesions: the WHO stance von Tan, Puay Hoon, Schnitt, Stuart J, van de Vijver, Marc J, Ellis, Ian O, Lakhani, Sunil R

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Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems von Dijk, Frederike, Veenstra, Veronique L., Soer, Eline C., Dings, Mark P. G., Zhao, Lan, Halfwerk, Johannes B., Hooijer, Gerrit K., Damhofer, Helene, Marzano, Marco, Steins, Anne, Waasdorp, Cynthia, Busch, Olivier R., Besselink, Marc G., Tol, Johanna A., Welling, Lieke, van Rijssen, Lennart B., Klompmaker, Sjors, Wilmink, Hanneke W., van Laarhoven, Hanneke W., Medema, Jan Paul, Vermeulen, Louis, van Hooff , Sander R., Koster, Jan, Verheij, Joanne, van de Vijver, Marc J., Wang, Xin, Bijlsma, Maarten F.

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Improving histotyping precision: The impact of immunohistochemical algorithms on epithelial ovarian cancer classification von Zelisse, Hein S., Dijk, Frederike, van Gent, Mignon D.J.M., Hooijer, Gerrit K.J., Mom, Constantijne H., van de Vijver, Marc J., Snijders, Malou L.H.

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Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas von Kreike, Bas, van Kouwenhove, Marieke, Horlings, Hugo, Weigelt, Britta, Peterse, Hans, Bartelink, Harry, van de Vijver, Marc J

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Pathological validation and prognostic potential of quantitative MRI in the characterization of pancreas cancer: preliminary experience von Klaassen, Remy, Steins, Anne, Gurney‐Champion, Oliver J., Bijlsma, Maarten F., Tienhoven, Geertjan, Engelbrecht, Marc R. W., Eijck, Casper H. J., Suker, Mustafa, Wilmink, Johanna W., Besselink, Marc G., Busch, Olivier R., Boer, Onno J., Vijver, Marc J., Hooijer, Gerrit K. J., Verheij, Joanne, Stoker, Jaap, Nederveen, Aart J., Laarhoven, Hanneke W. M.

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predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer von Knauer, Michael, Mook, Stella, Rutgers, Emiel J. T, Bender, Richard A, Hauptmann, Michael, van de Vijver, Marc J, Koornstra, Rutger H. T, Bueno-de-Mesquita, Jolien M, Linn, Sabine C, van 't Veer, Laura J

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An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer von Stemke-Hale, Katherine, Gonzalez-Angulo, Ana Maria, Lluch, Ana, Neve, Richard M, Kuo, Wen-Lin, Davies, Michael, Carey, Mark, Hu, Zhi, Guan, Yinghui, Sahin, Aysegul, Symmans, W Fraser, Pusztai, Lajos, Nolden, Laura K, Horlings, Hugo, Berns, Katrien, Hung, Mien-Chie, van de Vijver, Marc J, Valero, Vicente, Gray, Joe W, Bernards, René, Mills, Gordon B, Hennessy, Bryan T

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Using Microarray Analysis as a Prognostic and Predictive Tool in Oncology: Focus on Breast Cancer and Normal Tissue Toxicity von Nuyten, Dimitry S.A., MD, van de Vijver, Marc J., MD, PhD

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BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations von Holstege, Henne, Horlings, Hugo M, Velds, Arno, Langerød, Anita, Børresen-Dale, Anne-Lise, van de Vijver, Marc J, Nederlof, Petra M, Jonkers, Jos

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