The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic von Frankell, Alexander M., Jammula, SriGanesh, Li, Xiaodun, Contino, Gianmarco, Killcoyne, Sarah, Abbas, Sujath, Perner, Juliane, Bower, Lawrence, Devonshire, Ginny, Ococks, Emma, Grehan, Nicola, Mok, James, O’Donovan, Maria, MacRae, Shona, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C.

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Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data von Jammula, SriGanesh, Katz-Summercorn, Annalise C., Li, Xiaodun, Linossi, Constanza, Smyth, Elizabeth, Killcoyne, Sarah, Biasci, Daniele, Subash, Vinod V., Abbas, Sujath, Blasko, Adrienn, Devonshire, Ginny, Grantham, Amber, Wronowski, Filip, O’Donovan, Maria, Grehan, Nicola, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C., Noorani, Ayesha, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Hughes, Caitriona, Fidziukiewicz, Elwira, Bornschein, Jan, MacRae, Shona, Crawte, Jason, Northrop, Alex, Contino, Gianmarco, Li, Xiaodun, de la Rue, Rachel, O’Donovan, Maria, Miremadi, Ahmad, Malhotra, Shalini, Tripathi, Monika, Tavaré, Simon, Lynch, Andy G., Eldridge, Matthew, Secrier, Maria, Bower, Lawrence, Devonshire, Ginny, Perner, Juliane, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O’Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Igali, Laszlo, Scott, Michael, Sothi, Sharmila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Moorthy, Krishna, Peters, Christopher J., Grabowska, Anna, Turkington, Richard, Fitzgerald, Rebecca C.

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Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts von Sawas, Tarek, Killcoyne, Sarah, Iyer, Prasad G., Wang, Kenneth K., Smyrk, Thomas C., Kisiel, John B., Qin, Yi, Ahlquist, David A., Rustgi, Anil K., Costa, Rui J., Gerstung, Moritz, Fitzgerald, Rebecca C., Katzka, David A., Noorani, Ayesha, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Hughes, Caitriona, Fidziukiewicz, Elwira, Bornschein, Jan, MacRae, Shona, Crawte, Jason, Contino, Gianmarco, Li, Xiaodun, Rue, Rachel de la, O’Donovan, Maria, Miremad, Ahmad, Malhotra, Shalini, Tripathi, Monika, Tavaré, Simon, Lynch, Andy G., Eldridge, Matthew, Secrier, Maria, Bower, Lawrence, Devonshire, Ginny, Perner, Juliane, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O’Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Bunting, David, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Eneh, Victor, Igali, Laszlo, Scott, Michael, Sothi, Sharmila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Grabowska, Anna, Turkington, Richard

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Machine learning to predict early recurrence after oesophageal cancer surgery von Rahman, S. A., Walker, R. C., Lloyd, M. A., Grace, B. L., van Boxel, G. I., Kingma, B. F., Ruurda, J. P., van Hillegersberg, R., Harris, S., Parsons, S., Mercer, S., Griffiths, E. A., O'Neill, J. R., Turkington, R., Fitzgerald, R. C., Underwood, T. J., Noorani, Ayesha, Elliott, Rachael Fels, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Crawte, Jason, Chettouh, Hamza, Contino, Gianmarco, Li, Xiaodun, Gregson, Eleanor, Zeki, Sebastian, de la Rue, Rachel, Malhotra, Shalini, Tavaré, Simon, Lynch, Andy G., Smith, Mike L., Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O'Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Byrne, James P., Kelly, Jamie J., Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Chang, Andrew Davies Fuju, Zylstra, Janine, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Bunting, David, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Eneh, Victor, Igali, Laszlo, Scott, Michael, Sothi, Shamila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Grabowska, Anna

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Mutational signature dynamics shaping the evolution of oesophageal adenocarcinoma von Abbas, Sujath, Pich, Oriol, Devonshire, Ginny, Zamani, Shahriar A., Katz-Summercorn, Annalise, Killcoyne, Sarah, Cheah, Calvin, Nutzinger, Barbara, Grehan, Nicola, Lopez-Bigas, Nuria, Fitzgerald, Rebecca C., Secrier, Maria

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Disentangling oncogenic amplicons in esophageal adenocarcinoma von Ng, Alvin Wei Tian, McClurg, Dylan Peter, Wesley, Ben, Zamani, Shahriar A., Black, Emily, Miremadi, Ahmad, Giger, Olivier, Hoopen, Rogier ten, Devonshire, Ginny, Redmond, Aisling M., Grehan, Nicola, Jammula, Sriganesh, Blasko, Adrienn, Li, Xiaodun, Aparicio, Samuel, Tavaré, Simon, Nowicki-Osuch, Karol, Fitzgerald, Rebecca C.

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Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma von Mourikis, Thanos P., Benedetti, Lorena, Foxall, Elizabeth, Temelkovski, Damjan, Nulsen, Joel, Perner, Juliane, Cereda, Matteo, Lagergren, Jesper, Howell, Michael, Yau, Christopher, Fitzgerald, Rebecca C., Scaffidi, Paola, Ciccarelli, Francesca D.

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Author Correction: Disentangling oncogenic amplicons in esophageal adenocarcinoma von Ng, Alvin Wei Tian, McClurg, Dylan Peter, Wesley, Ben, Zamani, Shahriar A., Black, Emily, Miremadi, Ahmad, Giger, Olivier, Hoopen, Rogier ten, Devonshire, Ginny, Redmond, Aisling M., Grehan, Nicola, Jammula, Sriganesh, Blasko, Adrienn, Li, Xiaodun, Aparicio, Samuel, Tavaré, Simon, Nowicki-Osuch, Karol, Fitzgerald, Rebecca C.

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Multicentre validation of CT grey-level co-occurrence matrix features for overall survival in primary oesophageal adenocarcinoma von O’Shea, Robert, Withey, Samuel J., Owczarczyk, Kasia, Rookyard, Christopher, Gossage, James, Godfrey, Edmund, Jobling, Craig, Parsons, Simon L., Skipworth, Richard J. E., Goh, Vicky

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A decade of the Oesophageal Cancer Clinical and Molecular Stratification Consortium von Peters, C. J., Ang, Y., Ciccarelli, F. D., Coles, H., Coleman, H. G., Contino, G., Crosby, T., Devonshire, G., Eldridge, M., Freeman, A., Grehan, N., McCord, M., Nutzinger, B., Zamani, S., Parsons, S. L., Petty, R., Sharrocks, A. D., Skipworth, R. J. E., Smyth, E. C., Soomro, I., Underwood, T. J., Fitzgerald, R. C.

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Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma von Turkington, Richard C, Knight, Laura A, Blayney, Jaine K, Secrier, Maria, Douglas, Rosalie, Parkes, Eileen E, Sutton, Eilis K, Stevenson, Leanne, McManus, Damian, Halliday, Sophia, McCavigan, Andrena M, Logan, Gemma E, Walker, Steven M, Steele, Christopher J, Perner, Juliane, Bornschein, Jan, MacRae, Shona, Miremadi, Ahmad, McCarron, Eamon, McQuaid, Stephen, Arthur, Kenneth, James, Jacqueline A, O’Neill, Robert, Noble, Fergus, Underwood, Timothy J, Harkin, D Paul, Salto-Tellez, Manuel, Fitzgerald, Rebecca C, Kennedy, Richard D, Noorani, Ayesha, Edwards, Paul Aw, Grehan, Nicola, Nutzinger, Barbara, Hughes, Caitriona, Fidziukiewicz, Elwira, Crawte, Jason, Northrop, Alex, Contino, Gianmarco, Li, Xiaodun, La rue, Rachel De, O’donovan, Maria, Malhotra, Shalini, Tripathi, Monika, Tavaré, Simon, Lynch, Andy G, Eldridge, Matthew, Bower, Lawrence, Devonshire, Ginny, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J, Ang, Yeng, Preston, Shaun R, Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard Je, Hupp, Ted R, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Owsley, Jack, Barr, Hugh, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D, Sanders, Grant, Berrisford, Richard, Harden, Catherine, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L, Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Igali, Laszlo, Scott, Michael, Sothi, Sharmila, Suortamo, Sari, Lishman, Suzy, Hanna, George B, Moorthy, Krishna, Peters, Christopher J, Grabowska, Anna, Coleman, Helen

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Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction von Bornschein, Jan, Wernisch, Lorenz, Secrier, Maria, Miremadi, Ahmad, Perner, Juliane, MacRae, Shona, O'Donovan, Maria, Newton, Richard, Menon, Suraj, Bower, Lawrence, Eldridge, Matthew D., Devonshire, Ginny, Cheah, Calvin, Turkington, Richard, Hardwick, Richard H., Selgrad, Michael, Venerito, Marino, Malfertheiner, Peter, Fitzgerald, Rebecca C., Noorani, Ayesha, Elliott, Rachael Fels, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Crawte, Jason, Chettouh, Hamza, Contino, Gianmarco, Li, Xiaodun, Gregson, Eleanor, Zeki, Sebastian, Rue, Rachel, Malhotra, Shalini, Tavaré, Simon, Lynch, Andy G., Smith, Mike L., Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., Robert O'Neill, J., Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Bunting, David, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Eneh, Victor, Igali, Laszlo, Scott, Michael, Sothi, Shamila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Grabowska, Anna

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A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy von Noorani, Ayesha, Bornschein, Jan, Lynch, Andy G, Secrier, Maria, Achilleos, Achilleas, Eldridge, Matthew, Bower, Lawrence, Weaver, Jamie M J, Crawte, Jason, Ong, Chin-Ann, Shannon, Nicholas, MacRae, Shona, Grehan, Nicola, Nutzinger, Barbara, O'Donovan, Maria, Hardwick, Richard, Tavaré, Simon, Fitzgerald, Rebecca C

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Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas von Ng, Alvin Wei Tian, Contino, Gianmarco, Killcoyne, Sarah, Devonshire, Ginny, Hsu, Ray, Abbas, Sujath, Su, Jing, Redmond, Aisling M., Weaver, Jamie M. J., Eldridge, Matthew D., Tavaré, Simon, Edwards, Paul A. W., Fitzgerald, Rebecca C.

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Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1 von Garcia, Edwin, Hayden, Annette, Birts, Charles, Britton, Edward, Cowie, Andrew, Pickard, Karen, Mellone, Massimiliano, Choh, Clarisa, Derouet, Mathieu, Duriez, Patrick, Noble, Fergus, White, Michael J., Primrose, John N., Strefford, Jonathan C., Rose-Zerilli, Matthew, Thomas, Gareth J., Ang, Yeng, Sharrocks, Andrew D., Fitzgerald, Rebecca C., Underwood, Timothy J.

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Author Correction: Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1 von Garcia, Edwin, Hayden, Annette, Birts, Charles, Britton, Edward, Rogerson, Connor, Bleaney, Christopher W., Cowie, Andrew, Pickard, Karen, Mellone, Massimiliano, Choh, Clarisa, Derouet, Mathieu, Duriez, Patrick, Noble, Fergus, White, Michael J., Primrose, John N., Strefford, Jonathan C., Rose-Zerilli, Matthew, Thomas, Gareth J., Ang, Yeng, Sharrocks, Andrew D., Fitzgerald, Rebecca C., Underwood, Timothy J.

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The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes von Kazachenka, Anastasiya, Loong, Jane Hc, Attig, Jan, Young, George R, Ganguli, Piyali, Devonshire, Ginny, Grehan, Nicola, Ciccarelli, Francesca D, Fitzgerald, Rebecca C, Kassiotis, George

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USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication von Mackay, H.L, Stone, H.R, Ronson, G.E, Ellis, K, Lanz, A, Aghabi, Y, Walker, A.K, Starowicz, K, Garvin, A.J, Van Eijk, P, Koestler, S.A, Anthony, E.J, Piberger, A.L, Chauhan, A.S, Conway-Thomas, P, Vaitsiankova, A, Vijayendran, S, Beesley, J.F, Petermann, E, Brown, E.J, Densham, R.M, Reed, S.H, Dobbs, F, Saponaro, M, Morris, J.R

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USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication von Mackay, H.L, Stone, H.R, Ronson, G.E, Ellis, K, Lanz, A, Aghabi, Y, Walker, A.K, Starowicz, K, Garvin, A.J, Van Eijk, P, Koestler, S.A, Anthony, E.J, Piberger, A.L, Chauhan, A.S, Conway-Thomas, P, Vaitsiankova, A, Vijayendran, S, Beesley, J.F, Petermann, E, Brown, E.J, Densham, R.M, Reed, S.H, Dobbs, F, Saponaro, M, Morris, J.R

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Proteome, transcriptome and metabolome plasticity in closely related strains of Escherichia coli- K12 and its diversity during molecular evolution processes

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