Structure Property Relationships of Carboxylic Acid Isosteres von Lassalas, Pierrik, Gay, Bryant, Lasfargeas, Caroline, James, Michael J, Tran, Van, Vijayendran, Krishna G, Brunden, Kurt R, Kozlowski, Marisa C, Thomas, Craig J, Smith, Amos B, Huryn, Donna M, Ballatore, Carlo

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MEK1 mutations confer resistance to MEK and B-RAF inhibition von Emery, Caroline M, Vijayendran, Krishna G, Zipser, Marie C, Sawyer, Allison M, Niu, Lili, Kim, Jessica J, Hatton, Charles, Chopra, Rajiv, Oberholzer, Patrick A, Karpova, Maria B, MacConaill, Laura E, Zhang, Jianming, Gray, Nathanael S, Sellers, William R, Dummer, Reinhard, Garraway, Levi A

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Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer’s and Other Neurodegenerative Diseases von Cornec, Anne-Sophie, Monti, Ludovica, Kovalevich, Jane, Makani, Vishruti, James, Michael J, Vijayendran, Krishna G, Oukoloff, Killian, Yao, Yuemang, Lee, Virginia M.-Y, Trojanowski, John Q, Smith, Amos B, Brunden, Kurt R, Ballatore, Carlo

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An Oncogenic Role for ETV1 in Melanoma von JANE-VALBUENA, Judit, WIDLUND, Hans R, HAHN, William C, DUNCAN, Lyn M, RUBIN, Mark A, FISHER, David E, GARRAWAY, Levi A, PERNER, Sven, JOHNSON, Laura A, DIBNER, Aurora C, LIN, William M, BAKER, Alissa C, NAZARIAN, Rosalynn M, VIJAYENDRAN, Krishna G, SELLERS, William R

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Integrative analysis of the melanoma transcriptome von Berger, Michael F, Levin, Joshua Z, Vijayendran, Krishna, Sivachenko, Andrey, Adiconis, Xian, Maguire, Jared, Johnson, Laura A, Robinson, James, Verhaak, Roel G, Sougnez, Carrie, Onofrio, Robert C, Ziaugra, Liuda, Cibulskis, Kristian, Laine, Elisabeth, Barretina, Jordi, Winckler, Wendy, Fisher, David E, Getz, Gad, Meyerson, Matthew, Jaffe, David B, Gabriel, Stacey B, Lander, Eric S, Dummer, Reinhard, Gnirke, Andreas, Nusbaum, Chad, Garraway, Levi A

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The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic von Frankell, Alexander M., Jammula, SriGanesh, Li, Xiaodun, Contino, Gianmarco, Killcoyne, Sarah, Abbas, Sujath, Perner, Juliane, Bower, Lawrence, Devonshire, Ginny, Ococks, Emma, Grehan, Nicola, Mok, James, O’Donovan, Maria, MacRae, Shona, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C.

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Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data von Jammula, SriGanesh, Katz-Summercorn, Annalise C., Li, Xiaodun, Linossi, Constanza, Smyth, Elizabeth, Killcoyne, Sarah, Biasci, Daniele, Subash, Vinod V., Abbas, Sujath, Blasko, Adrienn, Devonshire, Ginny, Grantham, Amber, Wronowski, Filip, O’Donovan, Maria, Grehan, Nicola, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C., Noorani, Ayesha, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Hughes, Caitriona, Fidziukiewicz, Elwira, Bornschein, Jan, MacRae, Shona, Crawte, Jason, Northrop, Alex, Contino, Gianmarco, Li, Xiaodun, de la Rue, Rachel, O’Donovan, Maria, Miremadi, Ahmad, Malhotra, Shalini, Tripathi, Monika, Tavaré, Simon, Lynch, Andy G., Eldridge, Matthew, Secrier, Maria, Bower, Lawrence, Devonshire, Ginny, Perner, Juliane, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O’Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Igali, Laszlo, Scott, Michael, Sothi, Sharmila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Moorthy, Krishna, Peters, Christopher J., Grabowska, Anna, Turkington, Richard, Fitzgerald, Rebecca C.

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Mutational signature dynamics shaping the evolution of oesophageal adenocarcinoma von Abbas, Sujath, Pich, Oriol, Devonshire, Ginny, Zamani, Shahriar A., Katz-Summercorn, Annalise, Killcoyne, Sarah, Cheah, Calvin, Nutzinger, Barbara, Grehan, Nicola, Lopez-Bigas, Nuria, Fitzgerald, Rebecca C., Secrier, Maria

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A decade of the Oesophageal Cancer Clinical and Molecular Stratification Consortium von Peters, C. J., Ang, Y., Ciccarelli, F. D., Coles, H., Coleman, H. G., Contino, G., Crosby, T., Devonshire, G., Eldridge, M., Freeman, A., Grehan, N., McCord, M., Nutzinger, B., Zamani, S., Parsons, S. L., Petty, R., Sharrocks, A. D., Skipworth, R. J. E., Smyth, E. C., Soomro, I., Underwood, T. J., Fitzgerald, R. C.

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A decade of the Oesophageal Cancer Clinical and Molecular Stratification Consortium von Peters, C. j, Ang, Y, Ciccarelli, F. d, Coles, H, Coleman, H. g, Contino, G, Crosby, T, Devonshire, G, Eldridge, M, Freeman, A, Grehan, N, Mccord, M, Nutzinger, B, Zamani, S, Parsons, S. l, Petty, R, Sharrocks, Andrew, Skipworth, R. j. e, Smyth, E. c, Soomro, I, Underwood, T. j, Edwards, Paul a. w, Redmond, Aisling m, Loreno, Christine, Abbas, Sujath, O’donovan, Maria, Miremadi, Ahmad, Malhotra, Shalini, Tripathi, Monika, Cheah, Calvin, Millington, Curtis, Secrier, Maria, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Hardwick, Richard h, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen, Preston, Shaun r, Bagwan, Izhar, Save, Vicki, Hupp, Ted r, O’neill, J. robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Walker, Robert c, Grace, Ben l, Lagergren, Jesper, Gossage, James a, Davies, Andrew r, Chang, Fuju, Mahadeva, Ula, Goh, Vicky, Sanders, Grant, Berrisford, Richard, Chan, David, Cheong, Ed, Kumar, Bhaskar, Sreedharan, L, Kaye, Philip, Saunders, John h, Lovat, Laurence, Haidry, Rehan, Scott, Michael, Sothi, Sharmila, Lishman, Suzy, Hanna, George b, Moorthy, Krishna, Grabowska, Anna, Turkington, Richard c, Mcmanus, Damian, Bartlett, Freddie, Fitzgerald, R. c

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Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma von Mourikis, Thanos P., Benedetti, Lorena, Foxall, Elizabeth, Temelkovski, Damjan, Nulsen, Joel, Perner, Juliane, Cereda, Matteo, Lagergren, Jesper, Howell, Michael, Yau, Christopher, Fitzgerald, Rebecca C., Scaffidi, Paola, Ciccarelli, Francesca D.

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Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma von Turkington, Richard C, Knight, Laura A, Blayney, Jaine K, Secrier, Maria, Douglas, Rosalie, Parkes, Eileen E, Sutton, Eilis K, Stevenson, Leanne, McManus, Damian, Halliday, Sophia, McCavigan, Andrena M, Logan, Gemma E, Walker, Steven M, Steele, Christopher J, Perner, Juliane, Bornschein, Jan, MacRae, Shona, Miremadi, Ahmad, McCarron, Eamon, McQuaid, Stephen, Arthur, Kenneth, James, Jacqueline A, Eatock, Martin M, O’Neill, Robert, Noble, Fergus, Underwood, Timothy J, Harkin, D Paul, Salto-Tellez, Manuel, Fitzgerald, Rebecca C, Kennedy, Richard D

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