Trichostatin A Is a Histone Deacetylase Inhibitor with Potent Antitumor Activity against Breast Cancer in Vivo von VIGUSHIN, David M, ALI, Simak, PACE, Paul E, MIRSAIDI, Nina, ITO, Kazuhiro, ADCOCK, Ian, COOMBES, R. Charles

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Histone deacetylase inhibitors in cancer treatment von Vigushin, David M, Coombes, R Charles

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Quantification of cellular proliferation in tumor and normal tissues of patients with breast cancer by [18F]fluorothymidine -positron emission tomography imaging : Evaluation of an... von KENNY, Laura M, VIGUSHIN, David M, AL-NAHHAS, Adil, OSMAN, Safiye, LUTHRA, Sajinder K, SHOUSHA, Sami, COOMBES, R. Charles, ABOAGYE, Eric O

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Histone Deacetylase Inhibitor Trichostatin A Represses Estrogen Receptor α-Dependent Transcription and Promotes Proteasomal Degradation of Cyclin D1 in Human Breast Carcinoma Cell... von ALAO, John Patrick, LAM, Eric W.-F, ALI, Simak, BULUWELA, Laki, BORDOGNA, Walter, LOCKEY, Peter, VARSHOCHI, Rana, STAVROPOULOU, Alexandra V, COOMBES, R. Charles, VIGUSHIN, David M

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In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3' -deoxy-3'-[18F]fluorothymidine positron emission tomography von LEYTON, Julius, ALAO, John P, WORKMAN, Paul, VIGUSHIN, David M, ABOAGYE, Eric O, DA COSTA, Marco, STAVROPOULOU, Alexandra V, LATIGO, John R, PERUMAL, Meg, FILIAL, Radhakrishna, QIMIN HE, ATADJA, Peter, LAM, Eric W.-F

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Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease von VIGUSHIN, D. M, PEPYS, M. B, HAWKINS, P. N

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ICI182,780 Induces p21 Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor α from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Lin... von Varshochi, Rana, Halim, Faezah, Sunters, Andrew, Alao, John P., Madureira, Patricia A., Hart, Stephen M., Ali, Simak, Vigushin, David M., Coombes, R. Charles, Lam, Eric W.-F.

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Gliotoxin is a dual inhibitor of farnesyltransferase and geranylgeranyltransferase I with antitumor activity against breast cancer in vivo von Vigushin, D M, Mirsaidi, N, Brooke, G, Sun, C, Pace, P, Inman, L, Moody, C J, Coombes, R C

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Phase I and pharmacokinetic study of D-limonene in patients with advanced cancer von VIGUSHIN, D. M, POON, G. K, BODDY, A, ENGLISH, J, HALBERT, G. W, PAGONIS, C, JARMAN, M, COOMBES, R. C

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Human lysozyme gene mutations cause hereditary systemic amyloidosis von Pepys, M. B., Hawkins, P. N., Booth, D. R., Vigushin, D. M., Tennent, G. A., Soutar, A. K., Totty, N., Nguyen, O., Blake, C. C. F., Terry, C. J., Feest, T. G., Zalin, A. M., Hsuan, J. J.

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Managing malignant disease in patients with porphyria von Palmieri, C., Vigushin, D.M., Peters, T.J.

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Pyrazino[1,2-a]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I von VIGUSHIN, David M, BROOKE, Greg, WILLOWS, David, COOMBES, R. Charles, MOODY, Christopher J

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Stereodefined and polyunsaturated inhibitors of histone deacetylase based on (2 E,4 E)-5-arylpenta-2,4-dienoic acid hydroxyamides von Marson, Charles M., Serradji, Nawal, Rioja, Alphonso S., Gastaud, Sebastien P., Alao, John P., Coombes, R.Charles, Vigushin, David M.

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Two weekly vinorelbine: administration in patients who have received at least two prior chemotherapy regimes for advanced breast cancer von Udom, D.I., Vigushin, D.M., Linardou, H., Graham, H., Palmieri, C., Coombes, R.C.

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The Vincotube System: a design solution to prevent the accidental administration of intrathecal vinca alkaloids von Palmieri, Carlo, Barron, Neil, Vigushin, David M

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Apolipoprotein AI Mutation Arg-60 Causes Autosomal Dominant Amyloidosis von Soutar, Anne K., Hawkins, P. N., Vigushin, D. M., Tennent, Glenys A., Booth, Susanne E., Hutton, Therese, Nguyen, Oanh, Totty, N. F., Feest, T. G., Hsuan, J. J., Pepys, M. B.

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Histone deacetylase inhibitor, Trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells von Alao, JP, Stavropoulou, AV, Lam, EW-F, Coombes, RC, Vigushin, DM

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The Nuclear Oxysterol Receptor LXRα Is Expressed in the Normal Human Breast and in Breast Cancer von Vigushin, D. M., Dong, Y., Inman, L., Peyvandi, N., Alao, J. P., Sun, C., Ali, S., Niesor, E. J., Bentzen, C. L., Coombes, R. C.

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Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase von Marson, Charles M., Rioja, Alphonso S., Brooke, Greg, Coombes, R.Charles, Vigushin, David M.

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A new apolipoprotein Al variant, Trp50Arg, causes hereditary amyloidosis von BOOTH, D.R., TAN, S.Y., BOOTH, S.E., HSUAN, J.J., TOTTY, N.F., NGUYEN, O., HUTTON, T., VIGUSHIN, D.M., TENNENT, G.A., HUTCHINSON, W.L., THOMSON, N., SOUTAR, A.K., HAWKINS, P.N., PEPYS, M.B.

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