Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ von Liu, Chang, Chikina, Maria, Deshpande, Rahul, Menk, Ashley V., Wang, Ting, Tabib, Tracy, Brunazzi, Erin A., Vignali, Kate M., Sun, Ming, Stolz, Donna B., Lafyatis, Robert A., Chen, Wei, Delgoffe, Greg M., Workman, Creg J., Wendell, Stacy G., Vignali, Dario A.A.

Volltext

The composition and signaling of the IL-35 receptor are unconventional von Collison, Lauren W, Delgoffe, Greg M, Guy, Clifford S, Vignali, Kate M, Chaturvedi, Vandana, Fairweather, DeLisa, Satoskar, Abhay R, Garcia, K Christopher, Hunter, Christopher A, Drake, Charles G, Murray, Peter J, Vignali, Dario A A

Volltext

LAG3 associates with TCR–CD3 complexes and suppresses signaling by driving co-receptor–Lck dissociation von Guy, Clifford, Mitrea, Diana M., Chou, Po-Chien, Temirov, Jamshid, Vignali, Kate M., Liu, Xueyan, Zhang, Hui, Kriwacki, Richard, Bruchez, Marcel P., Watkins, Simon C., Workman, Creg J., Vignali, Dario A. A.

Volltext

Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity von Liu, Chang, Somasundaram, Ashwin, Manne, Sasikanth, Gocher, Angela M., Szymczak-Workman, Andrea L., Vignali, Kate M., Scott, Ellen N., Normolle, Daniel P., John Wherry, E., Lipson, Evan J., Ferris, Robert L., Bruno, Tullia C., Workman, Creg J., Vignali, Dario A. A.

Volltext

The inhibitory cytokine IL-35 contributes to regulatory T-cell function von COLLISON, Lauren W, WORKMAN, Creg J, KUO, Timothy T, BOYD, Kelli, YAO WANG, VIGNALI, Kate M, CROSS, Richard, SEHY, David, BLUMBERG, Richard S, VIGNALI, Dario A. A

Volltext

Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector von Vignali, Dario A A, Szymczak, Andrea L, Workman, Creg J, Wang, Yao, Vignali, Kate M, Dilioglou, Smaroula, Vanin, Elio F

Volltext

Distinct TCR signaling pathways drive proliferation and cytokine production in T cells von Guy, Clifford S, Vignali, Kate M, Temirov, Jamshid, Bettini, Matthew L, Overacre, Abigail E, Smeltzer, Matthew, Zhang, Hui, Huppa, Johannes B, Tsai, Yu-Hwai, Lobry, Camille, Xie, Jianming, Dempsey, Peter J, Crawford, Howard C, Aifantis, Iannis, Davis, Mark M, Vignali, Dario A A

Volltext

Epitope Mapping of Therapeutic Antibodies Targeting Human LAG3 von Agnihotri, Pragati, Mishra, Arjun K., Agarwal, Priyanka, Vignali, Kate M., Workman, Creg J., Vignali, Dario A. A., Mariuzza, Roy A.

Volltext

IFNγ-induction of TH1-like regulatory T cells controls antiviral responses von Gocher-Demske, Angela M., Cui, Jian, Szymczak-Workman, Andrea L., Vignali, Kate M., Latini, Julianna N., Pieklo, Gwen P., Kimball, Jesse C., Avery, Lyndsay, Cipolla, Ellyse M., Huckestein, Brydie R., Hedden, Lee, Meisel, Marlies, Alcorn, John F., Kane, Lawrence P., Workman, Creg J., Vignali, Dario A. A.

Volltext

Ebi3 Binding to IFN-γ and IL-10 Limits Their Function von Scott, Ellen N, Ye, Cheng, Yano, Hiroshi, Lipatova, Zhanna, Brunazzi, Erin, Vignali, Kate M, Workman, Creg J, Vignali, Dario A A

Volltext

A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells von Andrews, Lawrence P., Vignali, Kate M., Szymczak-Workman, Andrea L., Burton, Amanda R., Brunazzi, Erin A., Ngiow, Shin Foong, Harusato, Akihito, Sharpe, Arlene H., Wherry, E. John, Taniuchi, Ichiro, Workman, Creg J., Vignali, Dario A.A.

Volltext

Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development von Bettini, Matthew L, Chou, Po-Chein, Guy, Clifford S, Lee, Thomas, Vignali, Kate M, Vignali, Dario A A

Volltext

Generation of T-cell receptor retrogenic mice von Vignali, Dario A A, Holst, Jeff, Szymczak-Workman, Andrea L, Vignali, Kate M, Burton, Amanda R, Workman, Creg J

Volltext

Metalloproteases regulate T-cell proliferation and effector function via LAG-3 von Li, Nianyu, Wang, Yao, Forbes, Karen, Vignali, Kate M, Heale, Bret S, Saftig, Paul, Hartmann, Dieter, Black, Roy A, Rossi, John J, Blobel, Carl P, Dempsey, Peter J, Workman, Creg J, Vignali, Dario A A

Volltext

Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR von He, Yanan, Rangarajan, Sneha, Kerzic, Melissa, Luo, Ming, Chen, Yihong, Wang, Qian, Yin, Yiyuan, Workman, Creg J., Vignali, Kate M., Vignali, Dario A.A., Mariuzza, Roy A., Orban, John

Volltext

Membrane association of the CD3ε signaling domain is required for optimal T cell development and function von Bettini, Matthew L, Guy, Clifford, Dash, Pradyot, Vignali, Kate M, Hamm, David E, Dobbins, Jessica, Gagnon, Etienne, Thomas, Paul G, Wucherpfennig, Kai W, Vignali, Dario A A

Volltext

Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice von Vignali, Dario A A, Holst, Jeff, Vignali, Kate M, Burton, Amanda R

Volltext

The CD3ε Proline-Rich Sequence, and Its Interaction with Nck, Is Not Required for T Cell Development and Function von Szymczak, Andrea L., Workman, Creg J., Gil, Diana, Dilioglou, Smaroula, Vignali, Kate M., Palmer, Ed, Vignali, Dario A. A.

Volltext

The Majority of Immunogenic Epitopes Generate CD4+ T Cells That Are Dependent on MHC Class II-Bound Peptide-Flanking Residues von Arnold, Paula Y, La Gruta, Nicole L, Miller, Tim, Vignali, Kate M, Adams, P. Scott, Woodland, David L, Vignali, Dario A. A

Volltext

Cutting Edge: Virus-Specific CD4+ Memory T Cells in Nonlymphoid Tissues Express a Highly Activated Phenotype von Cauley, Linda S, Cookenham, Tres, Miller, Timothy B, Adams, Pamela S, Vignali, Kate M, Vignali, Dario A. A, Woodland, David L

Volltext