Peptidomimetics, a synthetic tool of drug discovery von Vagner, Josef, Qu, Hongchang, Hruby, Victor J

Volltext

Aged Brains Express Less Melanocortin Receptors, Which Correlates with Age-Related Decline of Cognitive Functions von Zhou, Yang, Chawla, Monica K., Rios-Monterrosa, Jose L., Wang, Lingzhi, Zempare, Marc A., Hruby, Victor J., Barnes, Carol A., Cai, Minying

Volltext

Development of N -Acetylated Dipalmitoyl- S -Glyceryl Cysteine Analogs as Efficient TLR2/TLR6 Agonists von Zhou, Yang, Banday, Abid H, Hruby, Victor J, Cai, Minying

Volltext

Recent Advances in the Realm of Allosteric Modulators for Opioid Receptors for Future Therapeutics von Remesic, Michael, Hruby, Victor J, Porreca, Frank, Lee, Yeon Sun

Volltext

Design, Structure-Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists von Sawyer, Jonathon R, Audie, Joseph A, Swanson, Jon, Diller, David, Santiago, Solimar, Gribkoff, Valentin K, Ackerman, Allison, Hruby, Victor J, Gobbo, Gianpaolo, Bellucci, Michael A, Glauser, William A, Pentelute, Brad L, Sawyer, Tomi K

Volltext

Multiple N-Methylation of MT-II Backbone Amide Bonds Leads to Melanocortin Receptor Subtype hMC1R Selectivity: Pharmacological and Conformational Studies von Doedens, Lucas, Opperer, Florian, Cai, Minying, Beck, Johannes G, Dedek, Matt, Palmer, Erin, Hruby, Victor J, Kessler, Horst

Volltext

Toward a Universal μ‑Agonist Template for Template-Based Alignment Modeling of Opioid Ligands von Wu, Zhijun, Hruby, Victor J

Volltext

Heterobivalent ligands target cell-surface receptor combinations in vivo von Xu, Liping, Josan, Jatinder S., Vagner, Josef, Caplan, Michael R., Hruby, Victor J., Mash, Eugene A., Lynch, Ronald M., Morse, David L., Gillies, Robert J.

Volltext

Multivalent peptide and peptidomimetic ligands for the treatment of pain without toxicities and addiction von Hruby, Victor J.

Volltext

MC4R biased signalling and the conformational basis of biological function selections von Liu, Zekun, Hruby, Victor J.

Volltext

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome von Fan, W, Boston, B.A, Kesterson, R.A, Hruby, V.J, Cone, R.D

Volltext

Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors von Zhang, Wenjun, Gardell, Shannon, Zhang, Dongqin, Xie, Jennifer Y., Agnes, Richard S., Badghisi, Hamid, Hruby, Victor J., Rance, Naomi, Ossipov, Michael H., Vanderah, Todd W., Porreca, Frank, Lai, Josephine

Volltext

Design of cyclic peptides with biological activities from biologically active peptides: the case of peptide modulators of melanocortin receptors von Hruby, Victor J.

Volltext

Sex-specific Mediation of Opioid-induced Hyperalgesia by the Melanocortin-1 Receptor von JUNI, Aaron, MINYING CAI, STANKOVA, Magda, WAXMAN, Amanda R, AROUT, Caroline, KLEIN, Gad, DAHAN, Albert, HRUBY, Victor J, MOGIL, Jeffrey S, KEST, Benjamin

Volltext

Multifunctional Enkephalin Analogs with a New Biological Profile: MOR/DOR Agonism and KOR Antagonism von Lee, Yeon Sun, Remesic, Michael, Ramos-Colon, Cyf, Wu, Zhijun, LaVigne, Justin, Molnar, Gabriella, Tymecka, Dagmara, Misicka, Aleksandra, Streicher, John M., Hruby, Victor J., Porreca, Frank

Volltext

Development and in Vivo Quantitative Magnetic Resonance Imaging of Polymer Micelles Targeted to the Melanocortin 1 Receptor von Barkey, Natalie M, Preihs, Christian, Cornnell, Heather H, Martinez, Gary, Carie, Adam, Vagner, Josef, Xu, Liping, Lloyd, Mark C, Lynch, Vincent M, Hruby, Victor J, Sessler, Jonathan L, Sill, Kevin N, Gillies, Robert J, Morse, David L

Volltext

Designing peptide receptor agonists and antagonists von Hruby, Victor J.

Volltext

Ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH 2 Lead to Potent and Selective Agonists at hMC1R and hMC4R von Zhou, Yang, Mowlazadeh Haghighi, Saghar, Sawyer, Jonathon R, Hruby, Victor J, Cai, Minying

Volltext

Heterobivalent Ligands Crosslink Multiple Cell-Surface Receptors: The Human Melanocortin-4 and δ-Opioid Receptors von Vagner, Josef, Xu, Liping, Handl, Heather L, Josan, Jatinder S, Morse, David L, Mash, Eugene A, Gillies, Robert J, Hruby, Victor J

Volltext

Enhanced targeting with heterobivalent ligands von Xu, Liping, Vagner, Josef, Josan, Jatinder, Lynch, Ronald M, Morse, David L, Baggett, Brenda, Han, Haiyong, Mash, Eugene A, Hruby, Victor J, Gillies, Robert J

Volltext