Multiscale Modeling in Drug Discovery and Development: Future Opportunities and Present Challenges von Vicini, P

Volltext

Systems Pharmacology for Drug Discovery and Development: Paradigm Shift or Flash in the Pan? von Vicini, P, van der Graaf, P H

Volltext

Why Has Model‐Informed Precision Dosing Not Yet Become Common Clinical Reality? Lessons From the Past and a Roadmap for the Future von Darwich, A S, Ogungbenro, K, Vinks, A A, Powell, J R, Reny, J‐L, Marsousi, N, Daali, Y, Fairman, D, Cook, J, Lesko, L J, McCune, J S, Knibbe, C A J, Wildt, S N, Leeder, J S, Neely, M, Zuppa, A F, Vicini, P, Aarons, L, Johnson, T N, Boiani, J, Rostami‐Hodjegan, A

Volltext

The integrated low-level trigger and readout system of the CERN NA62 experiment von Ammendola, R., Angelucci, B., Barbanera, M., Biagioni, A., Cerny, V., Checcucci, B., Fantechi, R., Gonnella, F., Koval, M., Krivda, M., Lamanna, G., Lupi, M., Lonardo, A., Papi, A., Parkinson, C., Pedreschi, E., Petrov, P., Piandani, R., Pinzino, J., Pontisso, L., Raggi, M., Soldi, D., Sozzi, M.S., Spinella, F., Venditti, S., Vicini, P.

Volltext

Precision medicine in the age of big data: The present and future role of large-scale unbiased sequencing in drug discovery and development von Vicini, P, Fields, O, Lai, E, Litwack, ED, Martin, A-M, Morgan, TM, Pacanowski, MA, Papaluca, M, Perez, OD, Ringel, MS, Robson, M, Sakul, H, Vockley, J, Zaks, T, Dolsten, M, Søgaard, M

Volltext

Clinical Pharmacology: a Discipline at the Nexus Between Translational Science and Precision Medicine: Commentary on “Enhancing Value of Clinical Pharmacodynamics in Oncology Drug... von Vicini, P, Roskos, LK

Volltext

Amoxicillin Pharmacokinetics in Pregnant Women: Modeling and Simulations of Dosage Strategies von Andrew, M A, Easterling, T R, Carr, D B, Shen, D, Buchanan, M L, Rutherford, T, Bennett, R, Vicini, P, Hebert, M F

Volltext

Whither Pharmacometrics?: Present State and Future Choices von Vicini, P, Smith, B P

Volltext

UniPR129 is a competitive small molecule Eph‐ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations von Hassan‐Mohamed, I, Giorgio, C, Incerti, M, Russo, S, Pala, D, Pasquale, E B, Zanotti, I, Vicini, P, Barocelli, E, Rivara, S, Mor, M, Lodola, A, Tognolini, M

Volltext

A Mechanistic, Multiscale Mathematical Model of Immunogenicity for Therapeutic Proteins: Part 1—Theoretical Model von Chen, X, Hickling, TP, Vicini, P

Volltext

Minimally invasive infrapubic inflatable penile prosthesis implant for erectile dysfunction: evaluation of efficacy, satisfaction profile and complications von Antonini, G, Busetto, G M, De Berardinis, E, Giovannone, R, Vicini, P, Del Giudice, F, Conti, S L, Gentile, V, Perito, P E

Volltext

2-Thiazolylimino/Heteroarylimino-5-arylidene-4-thiazolidinones as New Agents with SHP-2 Inhibitory Action von Geronikaki, A, Eleftheriou, P, Vicini, P, Alam, I, Dixit, A, Saxena, A. K

Volltext

Are We Optimizing Gestational Diabetes Treatment With Glyburide? The Pharmacologic Basis for Better Clinical Practice von Hebert, MF, Ma, X, Naraharisetti, SB, Krudys, KM, Umans, JG, Hankins, GDV, Caritis, SN, Miodovnik, M, Mattison, DR, Unadkat, JD, Kelly, EJ, Blough, D, Cobelli, C, Ahmed, MS, Snodgrass, WR, Carr, DB, Easterling, TR, Vicini, P

Volltext

A Mechanistic, Multiscale Mathematical Model of Immunogenicity for Therapeutic Proteins: Part 2—Model Applications von Chen, X, Hickling, TP, Vicini, P

Volltext

Ignorance is not bliss: Statistical power is not probability of trial success von Zierhut, ML, Bycott, P, Gibbs, MA, Smith, BP, Vicini, P

Volltext

Progress report on the online processing upgrade at the NA62 experiment von Ammendola, R., Biagioni, A., Ciardiello, A., Cretaro, P., Frezza, O., Lamanna, G., Lo Cicero, F., Lonardo, A., Martinelli, M., Piandani, R., Pontisso, L., Raggi, M., Simula, F., Soldi, D., Turisini, M., Vicini, P.

Volltext

A quantitative systems pharmacology model of blood coagulation network describes in vivo biomarker changes in non‐bleeding subjects von Lee, D., Nayak, S., Martin, S. W., Heatherington, A. C., Vicini, P., Hua, F.

Volltext

A phase I study of MEDI1873, a novel GITR agonist, in advanced solid tumors von Denlinger, C.S., Infante, J.R., Aljumaily, R., Naing, A., Chintakuntlawar, A., Rizvi, N.A., Ross, H., Gordon, M., Kumar, R., Ma, M., Yan, L., Vicini, P., Standifer, N., Cann, J., Perera, A., Durham, N., Krishnan, S., Balmanoukian, A.

Volltext

Geometrical modified nesbit corporoplasty to correct different types of penile curvature: description of the surgical procedure based on geometrical principles and long-term result... von Vicini, P, Di Nicola, S, Antonini, G, De Berardinis, E, Gentile, V, De Marco, F

Volltext

Magnesium sulphate for prevention of eclampsia: are intramuscular and intravenous regimens equivalent? A population pharmacokinetic study von Salinger, DH, Mundle, S, Regi, A, Bracken, H, Winikoff, B, Vicini, P, Easterling, T

Volltext