Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis von Follis, Ariele Viacava, Llambi, Fabien, Merritt, Parker, Chipuk, Jerry E., Green, Douglas R., Kriwacki, Richard W.

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Centrality of drug targets in protein networks von Viacava Follis, Ariele

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Discovery of Affinity‐Based Probes for Btk Occupancy Assays von Qiu, Hui, Caldwell, Richard, Liu‐Bujalski, Lesley, Goutopoulos, Andreas, Jones, Reinaldo, Potnick, Justin, Sherer, Brian, Bender, Andrew, Grenningloh, Roland, Xu, Daigen, Gardberg, Anna, Mochalkin, Igor, Johnson, Theresa, Viacava Follis, Ariele, Head, Jared, Morandi, Federica

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Discoveries and controversies in BCL‐2 protein‐mediated apoptosis von Zheng, Janet H., Viacava Follis, Ariele, Kriwacki, Richard W., Moldoveanu, Tudor

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Small-molecule perturbation of competing interactions between c-Myc and Max von Follis, Ariele Viacava, Hammoudeh, Dalia I., Daab, Andrew T., Metallo, Steven J.

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Large-Scale Assessment of Binding Free Energy Calculations in Active Drug Discovery Projects von Schindler, Christina E. M, Baumann, Hannah, Blum, Andreas, Böse, Dietrich, Buchstaller, Hans-Peter, Burgdorf, Lars, Cappel, Daniel, Chekler, Eugene, Czodrowski, Paul, Dorsch, Dieter, Eguida, Merveille K. I, Follows, Bruce, Fuchß, Thomas, Grädler, Ulrich, Gunera, Jakub, Johnson, Theresa, Jorand Lebrun, Catherine, Karra, Srinivasa, Klein, Markus, Knehans, Tim, Koetzner, Lisa, Krier, Mireille, Leiendecker, Matthias, Leuthner, Birgitta, Li, Liwei, Mochalkin, Igor, Musil, Djordje, Neagu, Constantin, Rippmann, Friedrich, Schiemann, Kai, Schulz, Robert, Steinbrecher, Thomas, Tanzer, Eva-Maria, Unzue Lopez, Andrea, Viacava Follis, Ariele, Wegener, Ansgar, Kuhn, Daniel

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Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling von Csizmok, Veronika, Follis, Ariele Viacava, Kriwacki, Richard W, Forman-Kay, Julie D

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Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases von Caldwell, Richard D, Qiu, Hui, Askew, Ben C, Bender, Andrew T, Brugger, Nadia, Camps, Montserrat, Dhanabal, Mohanraj, Dutt, Vikram, Eichhorn, Thomas, Gardberg, Anna S, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Healey, Brian, Hodous, Brian L, Huck, Bayard R, Johnson, Theresa L, Jones, Christopher, Jones, Reinaldo C, Mochalkin, Igor, Morandi, Federica, Nguyen, Ngan, Meyring, Michael, Potnick, Justin R, Santos, Dusica Cvetinovic, Schmidt, Ralf, Sherer, Brian, Shutes, Adam, Urbahns, Klaus, Follis, Ariele Viacava, Wegener, Ansgar A, Zimmerli, Simone C, Liu-Bujalski, Lesley

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Regulation of apoptosis by an intrinsically disordered region of Bcl-xL von Follis, Ariele Viacava, Llambi, Fabien, Kalkavan, Halime, Yao, Yong, Phillips, Aaron H., Park, Cheon-Gil, Marassi, Francesca M., Green, Douglas R., Kriwacki, Richard W.

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PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis von Follis, Ariele Viacava, Chipuk, Jerry E, Fisher, John C, Yun, Mi-Kyung, Grace, Christy R, Nourse, Amanda, Baran, Katherine, Ou, Li, Min, Lie, White, Stephen W, Green, Douglas R, Kriwacki, Richard W

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Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity von Qiu, Hui, Ali, Zahid, Bowlan, Julian, Caldwell, Richard, Gardberg, Anna, Glaser, Nina, Goutopoulos, Andreas, Head, Jared, Johnson, Theresa, Maurer, Christine, Georgi, Katrin, Grenningloh, Roland, Fang, Zhizhou, Morandi, Federica, Rohdich, Felix, Schmidt, Ralf, Follis, Ariele Viacava, Sherer, Brian

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Improved low molecular weight Myc-Max inhibitors von Wang, Huabo, Hammoudeh, Dalia I, Follis, Ariele Viacava, Reese, Brian E, Lazo, John S, Metallo, Steven J, Prochownik, Edward V

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Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitors von Qiu, Hui, Liu-Bujalski, Lesley, Caldwell, Richard D., Viacava Follis, Ariele, Gardberg, Anna, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Johnson, Theresa, Jones, Christopher C.V., Jones, Reinaldo, Mochalkin, Igor, Morandi, Federica, Neagu, Constantin, Potnick, Justin, Sherer, Brian

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Discovery of Novel Myc−Max Heterodimer Disruptors with a Three-Dimensional Pharmacophore Model von Mustata, Gabriela, Follis, Ariele Viacava, Hammoudeh, Dalia I, Metallo, Steven J, Wang, Huabo, Prochownik, Edward V, Lazo, John S, Bahar, Ivet

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From Functional Fatty Acids to Potent and Selective Natural-Product-Inspired Mimetics via Conformational Profiling von Markham, Lauren E., Koelblen, Thomas, Chobanian, Harry R., Follis, Ariele Viacava, Burris, Thomas P., Micalizio, Glenn C.

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Identification and Characterization of an Allosteric Inhibitory Site on Dihydropteroate Synthase von Hammoudeh, Dalia I, Daté, Mihir, Yun, Mi-Kyung, Zhang, Weixing, Boyd, Vincent A, Viacava Follis, Ariele, Griffith, Elizabeth, Lee, Richard E, Bashford, Donald, White, Stephen W

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Many players in BCL-2 family affairs von Moldoveanu, Tudor, Follis, Ariele Viacava, Kriwacki, Richard W., Green, Douglas R.

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Discovery of potent and selective reversible Bruton’s tyrosine kinase inhibitors von Qiu, Hui, Ali, Zahid, Bender, Andrew, Caldwell, Richard, Chen, Yi-Ying, Fang, Zhizhou, Gardberg, Anna, Glaser, Nina, Goettsche, Anja, Goutopoulos, Andreas, Grenningloh, Roland, Hanschke, Bettina, Head, Jared, Johnson, Theresa, Jones, Christopher, Jones, Reinaldo, Kulkarni, Shashank, Maurer, Christine, Morandi, Federica, Neagu, Constantin, Poetzsch, Sven, Potnick, Justin, Schmidt, Ralf, Roe, Katherine, Viacava Follis, Ariele, Wing, Carolyn, Zhu, Xiaohua, Sherer, Brian

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Structural Studies of Cytoplasmic P53 Interactions von Viacava Follis, Ariele, Kriwacki, Richard W.

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Multiple Independent Binding Sites for Small-Molecule Inhibitors on the Oncoprotein c-Myc von Hammoudeh, Dalia I, Follis, Ariele Viacava, Prochownik, Edward V, Metallo, Steven J

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