Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere von Mashiyama, Susan T, Malabanan, M Merced, Akiva, Eyal, Bhosle, Rahul, Branch, Megan C, Hillerich, Brandan, Jagessar, Kevin, Kim, Jungwook, Patskovsky, Yury, Seidel, Ronald D, Stead, Mark, Toro, Rafael, Vetting, Matthew W, Almo, Steven C, Armstrong, Richard N, Babbitt, Patricia C

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Discovery of new enzymes and metabolic pathways by using structure and genome context von Zhao, Suwen, Kumar, Ritesh, Sakai, Ayano, Vetting, Matthew W., Wood, B. McKay, Brown, Shoshana, Bonanno, Jeffery B., Hillerich, Brandan S., Seidel, Ronald D., Babbitt, Patricia C., Almo, Steven C., Sweedler, Jonathan V., Gerlt, John A., Cronan, John E., Jacobson, Matthew P.

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Structure and functions of the GNAT superfamily of acetyltransferases von Vetting, Matthew W., S. de Carvalho, Luiz Pedro, Yu, Michael, Hegde, Subray S., Magnet, Sophie, Roderick, Steven L., Blanchard, John S.

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The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase von Blanchard, John S, Vetting, Matthew W, Hegde, Subray S

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Prediction of enzymatic pathways by integrative pathway mapping von Calhoun, Sara, Korczynska, Magdalena, Wichelecki, Daniel J, San Francisco, Brian, Zhao, Suwen, Rodionov, Dmitry A, Vetting, Matthew W, Al-Obaidi, Nawar F, Lin, Henry, O'Meara, Matthew J, Scott, David A, Morris, John H, Russel, Daniel, Almo, Steven C, Osterman, Andrei L, Gerlt, John A, Jacobson, Matthew P, Shoichet, Brian K, Sali, Andrej

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A General Strategy for the Discovery of Metabolic Pathways: d‑Threitol, l‑Threitol, and Erythritol Utilization in Mycobacterium smegmatis von Huang, Hua, Carter, Michael S, Vetting, Matthew W, Al-Obaidi, Nawar, Patskovsky, Yury, Almo, Steven C, Gerlt, John A

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Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks von Zhao, Suwen, Sakai, Ayano, Zhang, Xinshuai, Vetting, Matthew W, Kumar, Ritesh, Hillerich, Brandan, San Francisco, Brian, Solbiati, Jose, Steves, Adam, Brown, Shoshana, Akiva, Eyal, Barber, Alan, Seidel, Ronald D, Babbitt, Patricia C, Almo, Steven C, Gerlt, John A, Jacobson, Matthew P

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Mechanistic and Structural Analysis of Aminoglycoside N-Acetyltransferase AAC(6′)-Ib and Its Bifunctional, Fluoroquinolone-Active AAC(6′)-Ib-cr Variant von Vetting, Matthew W, Park, Chi Hye, Hegde, Subray S, Jacoby, George A, Hooper, David C, Blanchard, John S

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Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily von Lukk, Tiit, Sakai, Ayano, Kalyanaraman, Chakrapani, Brown, Shoshana D, Imker, Heidi J, Song, Ling, Fedorov, Alexander A, Fedorov, Elena V, Toro, Rafael, Hillerich, Brandan, Seidel, Ronald, Patskovsky, Yury, Vetting, Matthew W, Nair, Satish K, Babbitt, Patricia C, Almo, Steven C, Gerlt, John A, Jacobson, Matthew P

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Evolution of Enzymatic Activities in the Enolase Superfamily: Galactarate Dehydratase III from Agrobacterium tumefaciens C58 von Groninger-Poe, Fiona P, Bouvier, Jason T, Vetting, Matthew W, Kalyanaraman, Chakrapani, Kumar, Ritesh, Almo, Steven C, Jacobson, Matthew P, Gerlt, John A

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Structural and Biochemical Analysis of the Pentapeptide Repeat Protein EfsQnr, a Potent DNA Gyrase Inhibitor von HEGDE, Subray S, VETTING, Matthew W, MITCHENALL, Lesley A, MAXWELL, Anthony, BLANCHARD, John S

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Discovery of Function in the Enolase Superfamily: d‑Mannonate and d‑Gluconate Dehydratases in the d‑Mannonate Dehydratase Subgroup von Wichelecki, Daniel J, Balthazor, Bryan M, Chau, Anthony C, Vetting, Matthew W, Fedorov, Alexander A, Fedorov, Elena V, Lukk, Tiit, Patskovsky, Yury V, Stead, Mark B, Hillerich, Brandan S, Seidel, Ronald D, Almo, Steven C, Gerlt, John A

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Structures and mechanisms of the mycothiol biosynthetic enzymes von Fan, Fan, Vetting, Matthew W, Frantom, Patrick A, Blanchard, John S

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The Active Site of O-Acetylserine Sulfhydrylase Is the Anchor Point for Bienzyme Complex Formation with Serine Acetyltransferase von BIN HUANG, VETTING, Matthew W, RODERICK, Steven L

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Crystallographic Comparison of Manganese- and Iron-Dependent Homoprotocatechuate 2,3-Dioxygenases von VETTING, Matthew W, WACKETT, Lawrence P, QUE, Lawrence JR, LIPSCOMB, John D, OHLENDORF, Douglas H

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Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine von Kumar, Ritesh, Zhao, Suwen, Vetting, Matthew W, Wood, B McKay, Sakai, Ayano, Cho, Kyuil, Solbiati, José, Almo, Steven C, Sweedler, Jonathan V, Jacobson, Matthew P, Gerlt, John A, Cronan, John E

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The 1.8 Å crystal structure of catechol 1,2-dioxygenase reveals a novel hydrophobic helical zipper as a subunit linker von Vetting, Matthew W, Ohlendorf, Douglas H

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Experimental Strategies for Functional Annotation and Metabolism Discovery: Targeted Screening of Solute Binding Proteins and Unbiased Panning of Metabolomes von Vetting, Matthew W, Al-Obaidi, Nawar, Zhao, Suwen, San Francisco, Brian, Kim, Jungwook, Wichelecki, Daniel J, Bouvier, Jason T, Solbiati, Jose O, Vu, Hoan, Zhang, Xinshuai, Rodionov, Dmitry A, Love, James D, Hillerich, Brandan S, Seidel, Ronald D, Quinn, Ronald J, Osterman, Andrei L, Cronan, John E, Jacobson, Matthew P, Gerlt, John A, Almo, Steven C

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Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars von Zhang, Xinshuai, Carter, Michael S., Vetting, Matthew W., San Francisco, Brian, Zhao, Suwen, Al-Obaidi, Nawar F., Solbiati, Jose O., Thiaville, Jennifer J., de Crécy-Lagard, Valérie, Jacobson, Matthew P., Almo, Steven C., Gerlt, John A.

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Structural and Enzymatic Analysis of MshA from Corynebacterium glutamicum: SUBSTRATE-ASSISTED CATALYSIS von Vetting, Matthew W, Frantom, Patrick A, Blanchard, John S

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