Discovery of new enzymes and metabolic pathways by using structure and genome context von Zhao, Suwen, Kumar, Ritesh, Sakai, Ayano, Vetting, Matthew W., Wood, B. McKay, Brown, Shoshana, Bonanno, Jeffery B., Hillerich, Brandan S., Seidel, Ronald D., Babbitt, Patricia C., Almo, Steven C., Sweedler, Jonathan V., Gerlt, John A., Cronan, John E., Jacobson, Matthew P.

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Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere von Mashiyama, Susan T, Malabanan, M Merced, Akiva, Eyal, Bhosle, Rahul, Branch, Megan C, Hillerich, Brandan, Jagessar, Kevin, Kim, Jungwook, Patskovsky, Yury, Seidel, Ronald D, Stead, Mark, Toro, Rafael, Vetting, Matthew W, Almo, Steven C, Armstrong, Richard N, Babbitt, Patricia C

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Structure and functions of the GNAT superfamily of acetyltransferases von Vetting, Matthew W., S. de Carvalho, Luiz Pedro, Yu, Michael, Hegde, Subray S., Magnet, Sophie, Roderick, Steven L., Blanchard, John S.

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Prediction of enzymatic pathways by integrative pathway mapping von Calhoun, Sara, Korczynska, Magdalena, Wichelecki, Daniel J, San Francisco, Brian, Zhao, Suwen, Rodionov, Dmitry A, Vetting, Matthew W, Al-Obaidi, Nawar F, Lin, Henry, O'Meara, Matthew J, Scott, David A, Morris, John H, Russel, Daniel, Almo, Steven C, Osterman, Andrei L, Gerlt, John A, Jacobson, Matthew P, Shoichet, Brian K, Sali, Andrej

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The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase von Blanchard, John S, Vetting, Matthew W, Hegde, Subray S

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Experimental Strategies for Functional Annotation and Metabolism Discovery: Targeted Screening of Solute Binding Proteins and Unbiased Panning of Metabolomes von Vetting, Matthew W, Al-Obaidi, Nawar, Zhao, Suwen, San Francisco, Brian, Kim, Jungwook, Wichelecki, Daniel J, Bouvier, Jason T, Solbiati, Jose O, Vu, Hoan, Zhang, Xinshuai, Rodionov, Dmitry A, Love, James D, Hillerich, Brandan S, Seidel, Ronald D, Quinn, Ronald J, Osterman, Andrei L, Cronan, John E, Jacobson, Matthew P, Gerlt, John A, Almo, Steven C

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Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks von Zhao, Suwen, Sakai, Ayano, Zhang, Xinshuai, Vetting, Matthew W, Kumar, Ritesh, Hillerich, Brandan, San Francisco, Brian, Solbiati, Jose, Steves, Adam, Brown, Shoshana, Akiva, Eyal, Barber, Alan, Seidel, Ronald D, Babbitt, Patricia C, Almo, Steven C, Gerlt, John A, Jacobson, Matthew P

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Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars von Zhang, Xinshuai, Carter, Michael S., Vetting, Matthew W., San Francisco, Brian, Zhao, Suwen, Al-Obaidi, Nawar F., Solbiati, Jose O., Thiaville, Jennifer J., de Crécy-Lagard, Valérie, Jacobson, Matthew P., Almo, Steven C., Gerlt, John A.

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A General Strategy for the Discovery of Metabolic Pathways: d‑Threitol, l‑Threitol, and Erythritol Utilization in Mycobacterium smegmatis von Huang, Hua, Carter, Michael S, Vetting, Matthew W, Al-Obaidi, Nawar, Patskovsky, Yury, Almo, Steven C, Gerlt, John A

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Structural and Enzymatic Analysis of MshA from Corynebacterium glutamicum: SUBSTRATE-ASSISTED CATALYSIS von Vetting, Matthew W, Frantom, Patrick A, Blanchard, John S

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Fluoroquinolone Resistance Protein from Mycobacterium tuberculosis That Mimics DNA von Hegde, Subray S, Vetting, Matthew W, Roderick, Steven L, Mitchenall, Lesley A, Maxwell, Anthony, Takiff, Howard E, Blanchard, John S

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A novel bifunctional transcriptional regulator of riboflavin metabolism in Archaea von Rodionova, Irina A, Vetting, Matthew W, Li, Xiaoqing, Almo, Steven C, Osterman, Andrei L, Rodionov, Dmitry A

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Novel Metabolic Pathways and Regulons for Hexuronate Utilization in Proteobacteria von Bouvier, Jason T, Sernova, Natalia V, Ghasempur, Salehe, Rodionova, Irina A, Vetting, Matthew W, Al-Obaidi, Nawar F, Almo, Steven C, Gerlt, John A, Rodionov, Dmitry A

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Mechanistic and Structural Analysis of Aminoglycoside N-Acetyltransferase AAC(6′)-Ib and Its Bifunctional, Fluoroquinolone-Active AAC(6′)-Ib-cr Variant von Vetting, Matthew W, Park, Chi Hye, Hegde, Subray S, Jacoby, George A, Hooper, David C, Blanchard, John S

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Functional assignment of multiple catabolic pathways for d-apiose von Carter, Michael S., Zhang, Xinshuai, Huang, Hua, Bouvier, Jason T., Francisco, Brian San, Vetting, Matthew W., Al-Obaidi, Nawar, Bonanno, Jeffrey B., Ghosh, Agnidipta, Zallot, Rémi G., Andersen, Harvey M., Almo, Steven C., Gerlt, John A.

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Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid von Blanchard, John S, Argyrou, Argyrides, Vetting, Matthew W, Aladegbami, Bola

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Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily von Lukk, Tiit, Sakai, Ayano, Kalyanaraman, Chakrapani, Brown, Shoshana D, Imker, Heidi J, Song, Ling, Fedorov, Alexander A, Fedorov, Elena V, Toro, Rafael, Hillerich, Brandan, Seidel, Ronald, Patskovsky, Yury, Vetting, Matthew W, Nair, Satish K, Babbitt, Patricia C, Almo, Steven C, Gerlt, John A, Jacobson, Matthew P

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Evolution of Enzymatic Activities in the Enolase Superfamily: Galactarate Dehydratase III from Agrobacterium tumefaciens C58 von Groninger-Poe, Fiona P, Bouvier, Jason T, Vetting, Matthew W, Kalyanaraman, Chakrapani, Kumar, Ritesh, Almo, Steven C, Jacobson, Matthew P, Gerlt, John A

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Structure of QnrB1, a Plasmid-mediated Fluoroquinolone Resistance Factor von Vetting, Matthew W., Hegde, Subray S., Wang, Minghua, Jacoby, George A., Hooper, David C., Blanchard, John S.

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Crystal structure of RimI from Salmonella typhimurium LT2, the GNAT responsible for N(alpha)-acetylation of ribosomal protein S18 von Vetting, Matthew W, Bareich, David C, Yu, Michael, Blanchard, John S

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